Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kathleen Moch"'
Autor:
Emily C Smith, Keith J Limbach, Nonenipha Rangel, Kyosuke Oda, Jessica S Bolton, Mengyan Du, Kalpana Gowda, Jianyang Wang, J Kathleen Moch, Sharvari Sonawane, Rachel Velasco, Arnel Belmonte, Rebecca Danner, Joanne M Lumsden, Noelle B Patterson, Martha Sedegah, Michael R Hollingdale, Thomas L Richie, John B Sacci, Eileen D Villasante, Joao C Aguiar
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232234 (2020)
Only a small fraction of the antigens expressed by malaria parasites have been evaluated as vaccine candidates. A successful malaria subunit vaccine will likely require multiple antigenic targets to achieve broad protection with high protective effic
Externí odkaz:
https://doaj.org/article/40acdf05876945a1bcc1de9efe418dee
Autor:
Garima Chopra, J. Kathleen Moch, Francis C. Motta, Christina M. Kelliher, Tomáš Gedeon, Lauren M. Smith, Adam R. Leman, Steven B. Haase, Bree Cummins, Norman C. Waters, John Harer, Robert R. Nerem, Kimberly Roche
Publikováno v:
Science. 368:754-759
Plasmodium 's inner clock Malarial fevers are notably regular, occurring when parasitized red blood cells rupture synchronously to release replicated parasites. It has long been speculated that the Plasmodium parasites that cause malaria must therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56132bd59fbd8d601df7e3b443f1cc96
https://doi.org/10.1126/science.aba4357
https://doi.org/10.1126/science.aba4357
Autor:
Sheetij Dutta, Lisa S. Dlugosz, Damien R. Drew, Xiaopeng Ge, Diouf Ababacar, Yazmin I. Rovira, J. Kathleen Moch, Meng Shi, Carole A. Long, Michael Foley, James G. Beeson, Robin F. Anders, Kazutoyo Miura, J. David Haynes, Adrian H. Batchelor
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/73b6ec42cfcb4ac0b527e0b95511ad87
Autor:
Sheetij Dutta, Lisa S Dlugosz, Damien R Drew, Xiaopeng Ge, Diouf Ababacar, Yazmin I Rovira, J Kathleen Moch, Meng Shi, Carole A Long, Michael Foley, James G Beeson, Robin F Anders, Kazutoyo Miura, J David Haynes, Adrian H Batchelor
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003840 (2013)
Malaria vaccine candidate Apical Membrane Antigen-1 (AMA1) induces protection, but only against parasite strains that are closely related to the vaccine. Overcoming the AMA1 diversity problem will require an understanding of the structural basis of c
Externí odkaz:
https://doaj.org/article/8b57d05c22124733aa9aa5fc66898def
Autor:
Nonenipha Rangel, Emily C. Smith, Joanne M. Lumsden, Mengyan Du, Noelle B. Patterson, Jianyang Wang, Sharvari Sonawane, Kalpana Gowda, Rebecca Danner, Kyosuke Oda, Michael R. Hollingdale, J. Kathleen Moch, Eileen D. Villasante, Thomas L. Richie, Rachel Velasco, Joao C. Aguiar, Martha Sedegah, Jessica Bolton, Keith Limbach, Arnel Belmonte, John B. Sacci
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232234 (2020)
PLoS ONE
PLoS ONE
Only a small fraction of the antigens expressed by malaria parasites have been evaluated as vaccine candidates. A successful malaria subunit vaccine will likely require multiple antigenic targets to achieve broad protection with high protective effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259a0c453f8da0563253e24dc2226e4a
https://doaj.org/article/40acdf05876945a1bcc1de9efe418dee
https://doaj.org/article/40acdf05876945a1bcc1de9efe418dee
Autor:
Lauren M, Smith, Francis C, Motta, Garima, Chopra, J Kathleen, Moch, Robert R, Nerem, Bree, Cummins, Kimberly E, Roche, Christina M, Kelliher, Adam R, Leman, John, Harer, Tomas, Gedeon, Norman C, Waters, Steven B, Haase
Publikováno v:
Science
The blood-stage infection of the malaria parasite, Plasmodium falciparum, exhibits ts a48-hour developmental cycle that culminates in the synchronous release of parasites from red blood cells, triggering 48-hour fever cycles in the host. This cycle c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99c628a14792baf18baf21fe30fa8bba
https://pubmed.ncbi.nlm.nih.gov/32409472
https://pubmed.ncbi.nlm.nih.gov/32409472
Autor:
B Kim Lee Sim, David L Narum, Rana Chattopadhyay, Adriana Ahumada, J David Haynes, Steven R Fuhrmann, Jennifer N Wingard, Hong Liang, J Kathleen Moch, Stephen L Hoffman
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18393 (2011)
The malaria parasite Plasmodium falciparum EBA-175 binds its receptor sialic acids on glycophorin A when invading erythrocytes. The receptor-binding region (RII) contains two cysteine-rich domains with similar cysteine motifs (F1 and F2). Functional
Externí odkaz:
https://doaj.org/article/35e4e1b5664b4a81873e4517b2968be5
Autor:
Carmenza Spadafora, Gordon A Awandare, Karen M Kopydlowski, Jozsef Czege, J Kathleen Moch, Robert W Finberg, George C Tsokos, José A Stoute
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000968 (2010)
Plasmodium falciparum is a highly lethal malaria parasite of humans. A major portion of its life cycle is dedicated to invading and multiplying inside erythrocytes. The molecular mechanisms of erythrocyte invasion are incompletely understood. P. falc
Externí odkaz:
https://doaj.org/article/93b10422577b498c9c5fe9579b2cfaed
Autor:
Michael J. Nold, David L. Narum, Dan E. Sturdevant, Karine Reiter, Scott J. Geromanos, Prakash Srinivasan, J. Kathleen Moch, Julian C. Rayner, Krishan Kumar, Thomas D. Otto, Vijayaraj Nagarajan, J. David Haynes, Raul Herrera, Stephen F. Porcella, R. Burke Squires
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Scientific Reports
Scientific Reports
The symptoms of malaria are brought about by blood-stage parasites, which are established when merozoites invade human erythrocytes. Our understanding of the molecular events that underpin erythrocyte invasion remains hampered by the short-period of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7001d0b0b4159c05222ea431c5a35d
https://eprints.gla.ac.uk/157840/1/157840.pdf
https://eprints.gla.ac.uk/157840/1/157840.pdf
Autor:
J. David Haynes, David L. Narum, Xavier Ambroggio, Prakash Srinivasan, Wandy L. Beatty, Louis H. Miller, John C. Boothroyd, Susan K. Pierce, Jessica S. Tyler, Ababacar Diouf, Raul Herrera, J. Kathleen Moch
Publikováno v:
Proceedings of the National Academy of Sciences. 108:13275-13280
The commitment of Plasmodium merozoites to invade red blood cells (RBCs) is marked by the formation of a junction between the merozoite and the RBC and the coordinated induction of the parasitophorous vacuole. Despite its importance, the molecular ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0326abbeb3b1c7d207560d5e1858b95
https://doi.org/10.1073/pnas.1110303108
https://doi.org/10.1073/pnas.1110303108