Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kathleen McKeever"'
Autor:
James C. Fulton, Pei-Ling Yu, Katherine E. Smith, Jose C. Huguet-Tapia, Owen Hudson, April Meeks, Tania Quesada, Kathleen McKeever, Jeremy T. Brawner
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 35, Iss 6, Pp 477-487 (2022)
Pitch canker, caused by the fungal pathogen Fusarium circinatum, is a global disease affecting many Pinus spp. Often fatal, this disease causes significant mortality in both commercially grown and natural pine forests and is an issue of current and g
Externí odkaz:
https://doaj.org/article/c9e69b479acd43699dca1b1df007647d
Autor:
Lili Wang, Claude C. Warzecha, Alexander Kistner, Jessica A. Chichester, Peter Bell, Elizabeth L. Buza, Zhenning He, M. Betina Pampena, Julien Couthouis, Sunjay Sethi, Kathleen McKeever, Michael R. Betts, Emil Kakkis, James M. Wilson, Samuel Wadsworth, Barbara A. Sullivan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 292-305 (2022)
Ornithine transcarbamylase deficiency is a rare X-linked genetic urea cycle disorder leading to episodes of acute hyperammonemia, adverse cognitive and neurological effects, hospitalizations, and in some cases death. DTX301, a non-replicating, recomb
Externí odkaz:
https://doaj.org/article/0bb545c351f24bafb56d6307da45c4b4
Publikováno v:
Clinical Pharmacology in Drug Development. 11:1264-1272
Triheptanoin is an odd-carbon, medium-chain triglyceride consisting of three fatty acids with seven carbons each on a glycerol backbone, indicated for the treatment of adult and pediatric patients with long-chain fatty acid oxidation disorders (LC-FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec2c643751b5180279d873d8aa0cf4b
https://doi.org/10.1002/cpdd.1145
https://doi.org/10.1002/cpdd.1145
Publikováno v:
Clinical Pharmacology in Drug Development
Long‐chain fatty acid oxidation disorders (LC‐FAODs) are a group of life‐threatening autosomal recessive disorders caused by defects in nuclear genes encoding mitochondrial enzymes involved in the conversion of dietary long‐chain fatty acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a91c4d67586a90492c42ba41d4a3626
https://doi.org/10.1002/cpdd.944
https://doi.org/10.1002/cpdd.944
Autor:
James C, Fulton, Pei-Ling, Yu, Katherine E, Smith, Jose C, Huguet-Tapia, Owen, Hudson, April, Meeks, Tania, Quesada, Kathleen, McKeever, Jeremy T, Brawner
Publikováno v:
Molecular plant-microbe interactions : MPMI. 35(6)
Pitch canker, caused by the fungal pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82aba4a15c701e87d2668098622764ed
https://pubmed.ncbi.nlm.nih.gov/35266808
https://pubmed.ncbi.nlm.nih.gov/35266808
Autor:
Stephen Weasel Scott, Rakesh Dixit, Gianluca Carlesso, Lily Cheng, Joel Leininger, Devon K. Taylor, Halie Cook, Molly Reed, Kathleen McKeever, Katie Streicher, Karma Dacosta, Raffaella Faggioni, Steve Eck, Ronald Herbst, Patricia C. Ryan, Simone M Nicholson
Publikováno v:
Reproductive Toxicology. 74:116-133
MEDI-570 is a fully human afucosylated monoclonal antibody (MAb) against Inducible T-cell costimulator (ICOS), highly expressed on CD4+ T follicular helper (TFH) cells. Effects of MEDI-570 were evaluated in an enhanced pre-postnatal development toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827b5c980a6b8749284315cb8c693c97
https://doi.org/10.1016/j.reprotox.2017.08.018
https://doi.org/10.1016/j.reprotox.2017.08.018
Autor:
Jack Shi, Julie Taylor, Wenjie Song, Kathleen McKeever, Yulan Qi, Simon Jones, Christine Haller
Publikováno v:
Clinical Pharmacokinetics
Introduction Mucopolysaccharidosis type VII (MPS VII, Sly Syndrome) is a progressive, debilitating, ultra-rare lysosomal storage disorder caused by the deficiency of β-glucuronidase (GUS), an enzyme required for breakdown of glycosaminoglycans (GAGs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d6939aed0f1f22037fe10295afefb5
https://pubmed.ncbi.nlm.nih.gov/30515718
https://pubmed.ncbi.nlm.nih.gov/30515718
Autor:
Frank R. Brennan, Lauren E. Black, Estelle Marrer-Berger, Melissa Schutten, Patricia C. Ryan, Gerhard F. Weinbauer, Kathleen McKeever, John L. Vahle, Joy A. Cavagnaro
Publikováno v:
mAbs. 10(1)
Monoclonal antibodies (mAbs) are improving the quality of life for patients suffering from serious diseases due to their high specificity for their target and low potential for off-target toxicity. The toxicity of mAbs is primarily driven by their ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27597e946902162a7d7061483a0b0a6f
https://pubmed.ncbi.nlm.nih.gov/28991509
https://pubmed.ncbi.nlm.nih.gov/28991509
Autor:
Katie Streicher, Christopher Morehouse, Yihong Yao, Fernanda Pilataxi, Kathleen McKeever, Koustubh Ranade, Ronald Herbst, Philip Brohawn, Brandon W. Higgs, Bahija Jallal, Laura Richman, Kim Lehmann, Steven A. Greenberg, Christopher Groves, David Fiorentino, Bhargavi Rajan
Publikováno v:
Arthritis & Rheumatology. 66:173-184
Objective Production of pathogenic autoantibodies by self-reactive plasma cells (PCs) is a hallmark of autoimmune diseases. We undertook this study to investigate the prevalence of PCs and their relationship to known pathogenic pathways to increase o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63925d1b4e35f730fb2407aa347ab2e2
https://doi.org/10.1002/art.38194
https://doi.org/10.1002/art.38194
Autor:
Yulan Qi, Kathleen McKeever, Julie Taylor, Christine Haller, Wenjie Song, Simon A. Jones, Jack Shi
Publikováno v:
Clinical Pharmacokinetics. 58:685-685
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84f33e2a292b9450cea6d611e75f61c4
https://doi.org/10.1007/s40262-018-0726-6
https://doi.org/10.1007/s40262-018-0726-6