Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kathleen McCaffrey"'
Publikováno v:
Microorganisms, Vol 9, Iss 4, p 705 (2021)
The unfolded protein response (UPR) is a homeostatic response to endoplasmic reticulum (ER) stress within eukaryotic cells. The UPR initiates transcriptional and post-transcriptional programs to resolve ER stress; or, if ER stress is severe or prolon
Externí odkaz:
https://doaj.org/article/1fcf403575cc43fc924488d1236df73b
Autor:
Niyas Kudukkil Pulloor, Sajith Nair, Kathleen McCaffrey, Aleksandar D Kostic, Pradeep Bist, Jeremy D Weaver, Andrew M Riley, Richa Tyagi, Pradeep D Uchil, John D York, Solomon H Snyder, Adolfo García-Sastre, Barry V L Potter, Rongtuan Lin, Stephen B Shears, Ramnik J Xavier, Manoj N Krishnan
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003981 (2014)
The pattern recognition receptor RIG-I is critical for Type-I interferon production. However, the global regulation of RIG-I signaling is only partially understood. Using a human genome-wide RNAi-screen, we identified 226 novel regulatory proteins of
Externí odkaz:
https://doaj.org/article/f96658edd07f4b1fb196fa2464f3ef81
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2523
Legionella pneumophila is an intracellular bacterial pathogen that uses a type IV secretion system (T4SS), termed Dot/Icm, to secrete more than 330 virulence effector proteins into the infected host cell. Many Dot/Icm effectors are involved in biogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1857487dc564c05390e23ac42087e5d8
https://pubmed.ncbi.nlm.nih.gov/35759189
https://pubmed.ncbi.nlm.nih.gov/35759189
Publikováno v:
Methods in Molecular Biology ISBN: 9781071624487
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cbfefafb054d5c8e893c254b9299e66
https://doi.org/10.1007/978-1-0716-2449-4_3
https://doi.org/10.1007/978-1-0716-2449-4_3
Publikováno v:
Microorganisms, Vol 9, Iss 705, p 705 (2021)
Microorganisms
Microorganisms
The unfolded protein response (UPR) is a homeostatic response to endoplasmic reticulum (ER) stress within eukaryotic cells. The UPR initiates transcriptional and post-transcriptional programs to resolve ER stress; or, if ER stress is severe or prolon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62c24d2d2cf6a2a8e08113547c34651
https://www.mdpi.com/2076-2607/9/4/705
https://www.mdpi.com/2076-2607/9/4/705
Autor:
Kathleen McCaffrey
Publikováno v:
Law and (Dis)Order in the Ancient Near East
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9cefea8e92c3e95c368f28f63a2d91a
https://doi.org/10.5325/j.ctv1g80975.20
https://doi.org/10.5325/j.ctv1g80975.20
Autor:
Patricia T. Vietheer, Irene Boo, Jun Gu, Kathleen McCaffrey, Stirling Edwards, Catherine Owczarek, Matthew P. Hardy, Louis Fabri, Rob J. Center, Pantelis Poumbourios, Heidi E. Drummer
Publikováno v:
Hepatology (Baltimore, Md.)
A vaccine that prevents hepatitis C virus (HCV) infection is urgently needed to support an emerging global elimination program. However, vaccine development has been confounded because of HCV's high degree of antigenic variability and the preferentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc0589031f8bfe955ebefeed24f7256
http://europepmc.org/articles/PMC5408392
http://europepmc.org/articles/PMC5408392
Autor:
Abha Chopra, Fasséli Coulibaly, Jun Gu, Heidi E. Drummer, Yousef M O Alhammad, Patricia Vietheer, Silvana Gaudieri, Joshua M. Hardy, Kathleen McCaffrey, Pantelis Poumbourios, Irene Boo
Publikováno v:
Journal of Virology
The hepatitis C virus (HCV) E2 glycoprotein is a major target of the neutralizing antibody (nAb) response, with multiple type-specific and broadly neutralizing antibody (bnAb) epitopes identified. The 412-to-423 region can generate bnAbs that block i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e37ed8ae6af79b3f6ea2e02a4e493cf
https://doi.org/10.1128/jvi.02066-17
https://doi.org/10.1128/jvi.02066-17
Autor:
Matthew P. Hardy, Louis Fabri, Heidi E. Drummer, Matthew A. Perugini, Pierre Scotney, Catherine M. Owczarek, Kathleen McCaffrey, Pantelis Poumbourios, Irene Boo
The hepatitis C virus (HCV) envelope glycoprotein E2 is the major target of broadly neutralizing antibodies in vivo and is the focus of efforts in the rational design of a universal B cell vaccine against HCV. The E2 glycoprotein exhibits a high degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0935f1a87ccb68e690f66d558d840917
https://europepmc.org/articles/PMC5309951/
https://europepmc.org/articles/PMC5309951/
Autor:
Niyas Kudukil Pulloor, Manoj N. Krishnan, Sajith Nair, Pradeep Bist, Yiliu Liu, Rongtuan Lin, Kathleen McCaffrey, Susana Soo Yeon Kim
Publikováno v:
Molecular and cellular biology. 37(6)
Transcription of type I interferon genes during RNA virus infection requires signal communication between several pattern recognition receptor (PRR)-adaptor complexes located at distinct subcellular membranous compartments and a central cytoplasmic T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c13f400864bb7adc15d289b61dcb0e0
https://pubmed.ncbi.nlm.nih.gov/27956705
https://pubmed.ncbi.nlm.nih.gov/27956705