A Non-Perturbative Molecular Grafting Strategy for Stable and Potent Therapeutic Peptide Ligands

Autor: Alan S. Kopin, Martin Beinborn, Micaella P Fagan, Jamie R. Doyle, David R. Haines, Maribel Rios, Kathleen M Sicinski, Venkata S. Raman, Yi Chi Song, Krishna Kumar, Vittorio Montanari, Benjamin N. Harwood

Publikováno v: ACS Central Science, Vol 7, Iss 3, Pp 454-466 (2021)
ACS Central Science

The gut-derived incretin hormone, glucagon-like peptide-1 (GLP1), plays an important physiological role in attenuating post-prandial blood glucose excursions in part by amplifying pancreatic insulin secretion. Native GLP1 is rapidly degraded by the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a981a6490ffab054d45057568971aa31
https://doaj.org/article/0801e8218c0d49fab074c95cdbfeee66

List of contributors

Autor: Rina Aharoni, Zulfiqar Ahmad, Suhail Akhtar, N. D. Prasad Atmuri, Carmen Avendaño, Ivneet Banga, Shai Bel, Łukasz Berlicki, Yair Blumberg, Carine Bourguet, Marlon Henrique Cardoso, Samraggi Choudhury, Sitan Diarra, Marvin N. Driessen, Michael K. Dunn, Vandon T. Duong, Offir Ertracht, Emer S. Ferro, Octavio Luiz Franco, Tatiana Galochkina, Sonu Gandhi, Shikun Ge, Jean-Christophe Gelly, Mayara C.F. Gewehr, Rujuta Ghorpade, Eric R. Gross, Wessal Hanout, Tamia A. Harris, Adrienne Joseph, Srinivasaraghavan Kannan, Abidemi Paul Kappo, Krishna Kumar, Maushmi S. Kumar, Dilraj Lama, Jolene L. Lau, Jianguo Li, Adi Litmanovich, Jamie Liu, William D. Lubell, Lloyd Mabonga, Subhasis Mahari, Priscilla Masamba, J. Carlos Menéndez, Gassan Moady, Satheesh Kumar Nanjappan, Ami Navon, Ines Neundorf, Meital Nuriel-Ohayon, Dmitriy Orlov, David Paul, Ron Piran, William Farias Porto, Nir Qvit, Samuel J.S. Rubin, Mussa Saad, Deepshikha Shahdeo, Olga Shamova, Kathleen M. Sicinski, Abhishek Singh, Worood Sirhan, Shruti Surendran, Simon Surprenant, Yaw Sing Tan, Mukesh Thakur, Ekaterina Umnyakova, Özge Ünsal, Chandra S Verma, Nana-Maria Wagner, Zhipeng A. Wang, Bryan J. Xie, Long Xu, Vanessa O. Zambelli, Xiaoying Zhang, Ji-Shen Zheng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cd1766f7274d84b4d2ea94b9168ec00
https://doi.org/10.1016/b978-0-12-820141-1.00034-0