Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kathleen M. Overholt"'
Autor:
Kathleen M. Overholt, Satoru Otsuru, Timothy S. Olson, Adam J. Guess, Victoria M. Velazquez, Laura Desbourdes, Massimo Dominici, Edwin M. Horwitz
Publikováno v:
Blood Advances, Vol 1, Iss 27, Pp 2667-2678 (2017)
Abstract: Hematopoietic stem cells (HSCs) reside in specialized microenvironments within the marrow designated as stem cell niches, which function to support HSCs at homeostasis and promote HSC engraftment after radioablation. We previously identifie
Externí odkaz:
https://doaj.org/article/b1458ca8466e41eda022d93f6c5cdbe8
Autor:
Kathleen M. Overholt, Melissa J. Rose, Sarita Joshi, Gail E. Herman, Rajinder Bajwa, Rolla Abu-Arja, Hemalatha G. Rangarajan, Edwin M. Horwitz
Publikováno v:
Blood Advances, Vol 1, Iss 4, Pp 279-281 (2017)
Externí odkaz:
https://doaj.org/article/b2ec1ee649fa44b9b81d9f243b1904a1
Autor:
Tyler S. Severance, Festus Njuguna, Gilbert Olbara, Maureen Kugo, Sandra Langat, Saskia Mostert, Larissa Klootwijk, Jodi Skiles, Scott L. Coven, Kathleen M. Overholt, Gertjan Kaspers, Terry A. Vik
Publikováno v:
Pediatric bloodcancerREFERENCES. 69(10)
Western Kenya is home to approximately 24 million people, with 10 million children under the age of 15 years.Here, we describe a multidisciplinary and sequential approach to better evaluate the complex factors affecting the lack of appropriate diagno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54ea1e2cb695899cd6ef0b7270fc16d
https://pubmed.ncbi.nlm.nih.gov/35593641
https://pubmed.ncbi.nlm.nih.gov/35593641
Autor:
Minjun Yu, Edwin M. Horwitz, Pratik A. Patel, Massimo Dominici, Kathleen M. Overholt, Linda Roback, Joseph R. Stanek, Suheyla Hasgur, Laura Desbourdes, Satoru Otsuru, Adam J. Guess, Theresa Relation
Publikováno v:
Cytotherapy
Mesenchymal stromal cells (MSCs) possess remarkable tumor tropism, making them ideal vehicles to deliver tumor-targeted therapeutic agents; however, their value in clinical medicine has yet to be realized. A barrier to clinical utilization is that on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3cea8b2082bc32dbcf3b2cc00dedc2
https://hdl.handle.net/11380/1251815
https://hdl.handle.net/11380/1251815
Autor:
Massimo Dominici, Kathleen M. Overholt, Laura Desbourdes, Victoria M. Velazquez, Satoru Otsuru, Edwin M. Horwitz, Timothy S. Olson, Adam J. Guess
Publikováno v:
Blood Advances. 1:2667-2678
Hematopoietic stem cells (HSCs) reside in specialized microenvironments within the marrow designated as stem cell niches, which function to support HSCs at homeostasis and promote HSC engraftment after radioablation. We previously identified marrow s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c4eecb028e18e4b23738d77e0ca3be
https://doi.org/10.1182/bloodadvances.2017008730
https://doi.org/10.1182/bloodadvances.2017008730
Publikováno v:
Case Reports in Hematology
Case Reports in Hematology, Vol 2015 (2015)
Case Reports in Hematology, Vol 2015 (2015)
A case of acute promyelocytic leukemia (APL) withRUNX1T1insertion to 7q is described and compared to reported cases of APL with negative retinoic acid receptor alpha (RARA) abnormality. In this report, we describe the case of a 2-year-old boy who pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c286de9456a71089bb1d4acd619670f2
https://doi.org/10.1155/2015/412016
https://doi.org/10.1155/2015/412016
Autor:
Ted J. Hofmann, Timothy S. Olson, Victoria M. Velazquez, Edwin M. Horwitz, Massimo Dominici, Takashi Kaito, Satoru Otsuru, Kathleen M. Overholt, Adam J. Guess
Despite years of extensive investigation, the cellular origin of heterotopic ossification (HO) has not been fully elucidated. We have previously shown that circulating bone marrow-derived osteoblast progenitor cells, characterized by the immunophenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2a161a2a8b39af7a39eb0d9e17b820
https://hdl.handle.net/11380/1117720
https://hdl.handle.net/11380/1117720
Autor:
Melissa J. Rose, Gail E. Herman, Hemalatha G. Rangarajan, Sarita Joshi, Kathleen M. Overholt, Rajinder P.S. Bajwa, Rolla Abu-Arja, Edwin M. Horwitz
Publikováno v:
Blood advances. 1(4)
Key Points HCT prior to onset of neurologic symptoms in children with OSTM1 osteopetrosis does not halt neurologic progression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d9c6c7bee4a50b9c126fb6828562ad
https://pubmed.ncbi.nlm.nih.gov/29296943
https://pubmed.ncbi.nlm.nih.gov/29296943
Autor:
Suheyla Hasgur, Laura M. Desbourdes, Adam J. Guess, Satoru Otsuru, Minjun Yu, Kathleen M. Overholt, Theresa Relation, Edwin M. Horwitz
Publikováno v:
The Journal of Immunology. 198:208.12-208.12
Human mesenchymal stromal cells (MSCs) are increasing used in clinical trials for a diverse array of applications. Whether allogenic or autologous cells are used, unqualified efficacy has not been shown, suggesting the innate immune system may be imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d708aa87c6dd31ec395c555dd571d3b7
https://doi.org/10.4049/jimmunol.198.supp.208.12
https://doi.org/10.4049/jimmunol.198.supp.208.12
Autor:
Edwin M. Horwitz, Adam J. Guess, Kathleen M Overholt, Laura M Desbourdes, Satoru Otsuru, Suheyla Hasgur, Minjun Yu
Publikováno v:
Blood. 128:5216-5216
Introduction The 5-year survival for patients with acute myeloid leukemia (AML) has stagnated for over two decades at about 60% for children, 40% for young adults, and Methods Bone marrow MSCs from C57BL/6 mouse were isolated and transduced with a le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fb173fd12e1ddc43f2ab5e523500c91
https://doi.org/10.1182/blood.v128.22.5216.5216
https://doi.org/10.1182/blood.v128.22.5216.5216