Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kathleen M. Mirrashidi"'
Autor:
Sarah K. Kummerfeld, Trinna L. Cuellar, Bettina L. Lee, Michael Reichelt, Benjamin Haley, Nobuhiko Kayagaki, Irma B. Stowe, Kathleen M. Mirrashidi, Colin K. Watanabe
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
The NLRC4 inflammasome recognizes bacterial flagellin and components of the type III secretion apparatus. NLRC4 stimulation leads to caspase-1 activation followed by a rapid lytic cell death known as pyroptosis. NLRC4 is linked to pathogen-free auto-
Autor:
Nobuhiko, Kayagaki, Bettina L, Lee, Irma B, Stowe, Opher S, Kornfeld, Karen, O'Rourke, Kathleen M, Mirrashidi, Benjamin, Haley, Colin, Watanabe, Merone, Roose-Girma, Zora, Modrusan, Sarah, Kummerfeld, Rohit, Reja, Yafei, Zhang, Vicky, Cho, T Daniel, Andrews, Lucy X, Morris, Christopher C, Goodnow, Edward M, Bertram, Vishva M, Dixit
Publikováno v:
Science signaling. 12(582)
Gasdermin-D (GSDMD) is cleaved by caspase-1, caspase-4, and caspase-11 in response to canonical and noncanonical inflammasome activation. Upon cleavage, GSDMD oligomerizes and forms plasma membrane pores, resulting in interleukin-1β (IL-1β) secreti
Autor:
Christopher C. Goodnow, Zora Modrusan, Irma B. Stowe, Rohit Reja, Bettina L. Lee, Sarah K. Kummerfeld, T. Daniel Andrews, Vishva M. Dixit, Benjamin Haley, Karen O'Rourke, Lucy X. Morris, Edward M. Bertram, Kathleen M. Mirrashidi, Yafei Zhang, Merone Roose-Girma, Nobuhiko Kayagaki, Vicky Cho, Colin K. Watanabe, Opher S. Kornfeld
Publikováno v:
Science Signaling. 12
Gasdermin-D (GSDMD) is cleaved by caspase-1, caspase-4, and caspase-11 in response to canonical and noncanonical inflammasome activation. Upon cleavage, GSDMD oligomerizes and forms plasma membrane pores, resulting in interleukin-1β (IL-1β) secreti
Autor:
Raphael H. Valdivia, Jessica Sherry, Tasha L. Johnson, Michael Shales, Nevan J. Krogan, Michael N. Starnbach, Joe Dan Dunn, Natali Gulbahce, Jeffery S. Cox, Gwendolyn M. Jang, Andrew J. Olive, Oren S. Rosenberg, Kathleen M. Mirrashidi, Isabelle Derré, John Von Dollen, Andrew Frando, Cherilyn A. Elwell, Erik Verschueren, Bennett H. Penn, Stefanie Jäger, Anusha M. Gopalakrishnan, Joanne N. Engel, Jeffrey R. Johnson
Publikováno v:
Cell host & microbe, vol 18, iss 1
Summary Chlamydia trachomatis is a leading cause of genital and ocular infections for which no vaccine exists. Upon entry into host cells, C. trachomatis resides within a membrane-bound compartment—the inclusion—and secretes inclusion membrane pr
Autor:
Kathleen M. Mirrashidi, Oren S. Rosenberg, Nadine Czudnochowski, Nevan J. Krogan, Rachel Nakagawa, Jeffrey R. Johnson, Joanne N. Engel, John Von Dollen, Cherilyn A. Elwell
Publikováno v:
Elwell, CA; Czudnochowski, N; von Dollen, J; Johnson, JR; Nakagawa, R; Mirrashidi, K; et al.(2017). Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. eLife, 6. doi: 10.7554/eLife.22709. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/8m91r5q1
ELIFE, vol 6
Elwell, CA; Czudnochowski, N; von Dollen, J; Johnson, JR; Nakagawa, R; Mirrashidi, K; et al.(2017). Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. ELIFE, 6. doi: 10.7554/e.Life.22709. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1zd3z70c
eLife, Vol 6 (2017)
eLife
ELIFE, vol 6
Elwell, CA; Czudnochowski, N; von Dollen, J; Johnson, JR; Nakagawa, R; Mirrashidi, K; et al.(2017). Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. ELIFE, 6. doi: 10.7554/e.Life.22709. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1zd3z70c
eLife, Vol 6 (2017)
eLife
Chlamydia trachomatis is an obligate intracellular pathogen that resides in a membrane-bound compartment, the inclusion. The bacteria secrete a unique class of proteins, Incs, which insert into the inclusion membrane and modulate the host-bacterium i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45c3c5c682b0ccb46a1de8d3caf1392
http://www.escholarship.org/uc/item/8m91r5q1
http://www.escholarship.org/uc/item/8m91r5q1
Autor:
Joanne N. Engel, Nadine Czudnochowski, John Von Dollen, Kathleen M. Mirrashidi, Jeffrey R. Johnson, Oren S. Rosenberg, Cherilyn A. Elwell, Nevan J. Krogan, Rachel Nakagawa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f90b229e70cf0113f0f32459ada6d477
https://doi.org/10.7554/elife.22709.019
https://doi.org/10.7554/elife.22709.019
Publikováno v:
Nature reviews. Microbiology. 14(6)
Chlamydia spp. are important causes of human disease for which no effective vaccine exists. These obligate intracellular pathogens replicate in a specialized membrane compartment and use a large arsenal of secreted effectors to survive in the hostile