Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kathleen M. Dickson"'
Autor:
Joshua Colby, Robert Nicholson, Kathleen M. Dickson, Wayel Orfali, Roland Naef, Ueli Suter, G.Jackson Snipes
Publikováno v:
Neurobiology of Disease, Vol 7, Iss 6, Pp 561-573 (2000)
Missense mutations in the murine peripheral myelin protein-22 gene (Pmp22) underly the neuropathies in the trembler (Tr) and trembler-J (Tr-J) mice and in some humans with Charcot-Marie-Tooth disease. We have generated replication-defective adenoviru
Externí odkaz:
https://doaj.org/article/9d97697b5fe247b3b504f363595f6223
Publikováno v:
Journal of Neurochemistry. 116:396-405
Injury-induced expression of p75 neurotrophin receptor (p75NTR) in the CNS induces neuronal apoptosis and prevents neuronal regrowth. The mechanisms regulating injury-induced p75NTR expression are poorly characterized but previous studies have establ
Autor:
Wai Chi Ho, Alain Boudreault, Snezana Milutinovic, Kathleen M. Dickson, Philip A. Barker, John W. Gillard, James B. Jaquith, Stephen Morris, Jon P. Durkin, Mathieu J.M. Bertrand
Publikováno v:
Molecular Cell. 30(6):689-700
Summary The inhibitor of apoptosis (IAP) family of proteins enhances cell survival through mechanisms that remain uncertain. In this report, we show that cIAP1 and cIAP2 promote cancer cell survival by functioning as E3 ubiquitin ligases that maintai
Autor:
Amir H. Salehi, Kathleen M. Dickson, Stephen J. Morris, Jon P. Durkin, Wai-Chi Ho, John W. Gillard, Snezana Milutinovic, Genevieve Doucet, Philip A. Barker
Publikováno v:
Chemistry & Biology. 13(2):213-223
SummaryWe describe a group of small-molecule inhibitors of Jun kinase (JNK)-dependent apoptosis. AEG3482, the parental compound, was identified in a screening effort designed to detect compounds that reduce apoptosis of neonatal sympathetic neurons a
Publikováno v:
Calcified Tissue International. 68:304-315
Previous studies have shown endothelial cells to be a major target for endocrine TGF-beta in several soft tissues in the normal growing rat. The potent effect of TGF-beta1 on bone formation prompted us to analyze in detail the localization of specifi
Autor:
Roland Naef, G. Jackson Snipes, Joshua Colby, Wayel Orfali, Kathleen M. Dickson, Ueli Suter, Robert Nicholson
Publikováno v:
Neurobiology of Disease, Vol 7, Iss 6, Pp 561-573 (2000)
Missense mutations in the murine peripheral myelin protein-22 gene (Pmp22) underly the neuropathies in the trembler (Tr) and trembler-J (Tr-J) mice and in some humans with Charcot-Marie-Tooth disease. We have generated replication-defective adenoviru
Publikováno v:
Glia. 18:11-26
In neonatal mice, an acute injury produced by a stab wound to the cortex results in minimal astrocyte reactivity, as has been observed by others. However, if the source of the stab wound, a piece of nitrocellulose (NC) membrane, were now implanted in
Autor:
Frédéric Lebrun-Julien, Philippe Bourgeois, Derek Bowie, Kathleen M. Dickson, L. Duplan, Philip A. Barker, Przemyslaw Sapieha, Ingrid K. Osswald, Adriana Di Polo, Vincent Pernet
The central hypothesis of excitotoxicity is that excessive stimulation of neuronal NMDA-sensitive glutamate receptors is harmful to neurons and contributes to a variety of neurological disorders. Glial cells have been proposed to participate in excit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6ae9b8bd360404d5a9080af7ac0043
https://europepmc.org/articles/PMC6665839/
https://europepmc.org/articles/PMC6665839/
Publikováno v:
Developmental Biology. 148:590-601
Epidermal growth factor (EGF) is a peptide shown to effect precocious incisor tooth eruption in rat pups. Binding sites for EGF were visualized in the continuously erupting adult rat incisor by light and electron microscope radioautography after in v
Autor:
Wai Chi Ho, Stephanie Forte, Philip A. Barker, Kristy Favell, Kathleen M. Dickson, Jacqueline Boutilier, Alberto Javier Ramos
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(6)
Injury-induced expression of the p75 neurotrophin receptor (p75NTR) in the CNS facilitates neuronal apoptosis and prevents neuronal regrowth, but the mechanisms regulating p75NTR expression are poorly characterized. In this study, we showed that hypo