Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kathleen M. Attwood"'
Publikováno v:
Frontiers in Genetics, Vol 4 (2013)
Genomic instability is both a hallmark of cancer and a major contributing factor to tumour development. Central to the maintenance of genome stability is the repair of DNA damage, and the most toxic form of DNA damage is the DNA double-strand break.
Externí odkaz:
https://doaj.org/article/8b3bfb61ada34b2d96ef00fcc01cae28
Autor:
Kathleen M. Attwood, Michel Roberge, Lauren P Westhaver, Inhwa Kim, David M. Brandman, Aaron Robichaud, Patricia Colp, Jennifer A. Corcoran, Aruna D. Balgi, Craig McCormick, Elizabeth L. Castle, Sidney E Croul, Adrienne Weeks
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 11, Pp 1-18 (2020)
Cell Death and Disease, Vol 11, Iss 11, Pp 1-18 (2020)
Glioblastoma (GBM) is the most common primary malignant brain tumor, and it has a uniformly poor prognosis. Hypoxia is a feature of the GBM microenvironment, and previous work has shown that cancer cells residing in hypoxic regions resist treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba89f44e3d9da3e7d35533ae1f98ef52
http://europepmc.org/articles/PMC7673037
http://europepmc.org/articles/PMC7673037
Autor:
Graham Dellaire, Sabateeshan Mathavarajah, Carter Van Iderstine, Kathleen M. Attwood, Jayme Salsman, Dudley Chung
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 98(3)
Promyelocytic leukemia nuclear bodies (PML NBs) are nuclear subdomains that respond to genotoxic stress by increasing in number via changes in chromatin structure. However, the role of the PML protein and PML NBs in specific mechanisms of DNA repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f670f21d065ade6e4403ff50ef26a55
https://pubmed.ncbi.nlm.nih.gov/31671275
https://pubmed.ncbi.nlm.nih.gov/31671275
Autor:
Mélanie Rogier, Anastazja Grabarz, Tibor Pankotai, Audrey Furst, Leonid Andronov, Graham Dellaire, Evi Soutoglou, Kathleen M. Attwood, Pascal Kessler, Charlène Lemaître, Bruno P. Klaholz, Vincent Heyer, Bernardo Reina-San-Martin, Katerina Tsouroula
Faithful DNA repair is essential to avoid chromosomal rearrangements and promote genome integrity. Nuclear organization has emerged as a key parameter in the formation of chromosomal translocations, yet little is known as to whether DNA repair can ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65ddb8386565bce469383ea2a565204
http://publicatio.bibl.u-szeged.hu/5762/
http://publicatio.bibl.u-szeged.hu/5762/
Autor:
Amélie Rodrigue, Christi Andrin, Darin McDonald, Michael J. Hendzel, Razmik Mirzayans, Kathleen M. Attwood, Graham Dellaire, Sunita Ghosh, Jean-Yves Masson
Publikováno v:
Nucleus (Austin, Tex.). 3(4)
Nuclear actin is involved in several nuclear processes from chromatin remodeling to transcription. Here we examined the requirement for actin polymerization in DNA double-strand break repair. Double-strand breaks are considered the most dangerous typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d1dc178264b9cec395806cb75debad
https://pubmed.ncbi.nlm.nih.gov/22688650
https://pubmed.ncbi.nlm.nih.gov/22688650
Autor:
Nicholle Charette, Denis J. Dupré, Graham Dellaire, Patrick Holland, Yi-Qun Kuang, Jennifer Frazer, Kathleen M. Attwood
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40522 (2012)
PLoS ONE
PLoS ONE
Chemokine receptors are members of the G protein-coupled receptor (GPCR) family. CCR5 and CXCR4 act as co-receptors for human immunodeficiency virus (HIV) and several efforts have been made to develop ligands to inhibit HIV infection by blocking thos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a3ef1e823fde1674e135711de35dce
http://europepmc.org/articles/PMC3398031?pdf=render
http://europepmc.org/articles/PMC3398031?pdf=render
Publikováno v:
Cell cycle (Georgetown, Tex.). 10(2)
The promyelocytic leukemia (PML) protein is the main structural component of subnuclear domains termed PML nuclear bodies (PML NBs), which are implicated in tumor suppression by regulating apoptosis, cell senescence, and DNA repair. Previously, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d9af9d2190e90ea42f1ecb7087288a
https://pubmed.ncbi.nlm.nih.gov/21325882
https://pubmed.ncbi.nlm.nih.gov/21325882
Autor:
Yi-Qun Kuang, Nicholle Charette, Jennifer Frazer, Patrick J Holland, Kathleen M Attwood, Graham Dellaire, Denis J Dupré
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40522 (2012)
Chemokine receptors are members of the G protein-coupled receptor (GPCR) family. CCR5 and CXCR4 act as co-receptors for human immunodeficiency virus (HIV) and several efforts have been made to develop ligands to inhibit HIV infection by blocking thos
Externí odkaz:
https://doaj.org/article/86f6c226d9864aaf982e15f0050cdfc2