Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Kathleen M Sakamoto"'
Autor:
Andy Y Wen, Elliot M Landaw, Rachel Ochoa, Michelle Cho, Alex Chao, Gregory Lawson, Kathleen M Sakamoto
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55866 (2013)
Cyclic AMP-response element-binding protein (CREB) is a transcription factor implicated in growth factor-dependent cell proliferation and survival, glucose homeostasis, spermatogenesis, circadian rhythms, and synaptic plasticity associated with memor
Externí odkaz:
https://doaj.org/article/75548741c0c64e87a82a55f0799038bf
Autor:
Tara L Lin, Qiuju H Wang, Patrick Brown, Craig Peacock, Akil A Merchant, Sarah Brennan, Evan Jones, Karen McGovern, D Neil Watkins, Kathleen M Sakamoto, William Matsui
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15262 (2010)
Conserved embryonic signaling pathways such as Hedgehog (Hh), Wingless and Notch have been implicated in the pathogenesis of several malignancies. Recent data suggests that Hh signaling plays a role in normal B-cell development, and we hypothesized t
Externí odkaz:
https://doaj.org/article/f35b4f3911d34a378fc5bc900f362e5c
Autor:
Anil Kumar, Min Huang, Norman J. Lacayo, Holden T. Maecker, Stephen J. Forman, Srividya Swaminathan, Caroline Duault, Jianhua Yu, Steven T. Rosen, Anthony Chan, Martin Carroll, Adeleh Taghi Khani, Soraya Aramburo, Ashly Sanchez Ortiz, Sung June Lee, Tinisha McDonald, Kathleen M. Sakamoto, Christian Hurtz, Sarah K. Tasian, Lucy Ghoda, Guido Marcucci, Zhaohui Gu, Saro Armenian, Shai Izraeli, Chun-Wei Chen, Michael A. Caligiuri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background Type I interferons (IFN-Is), secreted by hematopoietic cells, drive immune surveillance of solid tumors. However, the mechanisms of suppression of IFN-I-driven immune responses in hematopoietic malignancies including B-cell acute lymphobla
Externí odkaz:
https://doaj.org/article/fe41859c6f9543c091bbe4f40f81980e
Publikováno v:
Haematologica, Vol 108, Iss 5 (2022)
Diamond-Blackfan anemia (DBA) is a ribosomopathy that is characterized by macrocytic anemia, congenital malformations, and early onset during childhood. Genetic studies have demonstrated that most patients carry mutations in one of the 20 related gen
Externí odkaz:
https://doaj.org/article/823a1fa0bda64500b5bfe45aa6620b62
Autor:
Agnes Reschke, Rebecca M. Richards, Stephanie M. Smith, Adrienne H. Long, Lianna J. Marks, Liora Schultz, Jennifer L. Kamens, Catherine Aftandilian, Kara L. Davis, Tanja Gruber, Kathleen M. Sakamoto
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Clinical pathways are evidence-based tools that have been integrated into many aspects of pediatric hospital medicine and have proven effective at reducing in-hospital complications from a variety of diseases. Adaptation of similar tools for specific
Externí odkaz:
https://doaj.org/article/8332e18e0fec4a0eaad8f1efab2764b2
Autor:
Stephanie M. Smith, Himalee S. Sabnis, Rebecca Williamson Lewis, Karen E. Effinger, John Bergsagel, Briana Patterson, Ann Mertens, Kathleen M. Sakamoto, Lidia Schapira, Sharon M. Castellino
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Targeted anticancer therapies such as BCR-ABL tyrosine kinase inhibitors (TKIs) have improved outcomes for chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL). However, littl
Externí odkaz:
https://doaj.org/article/f2ab9f70ca934309a8d50dc404b21711
Autor:
Minyoung Youn, Haigen Huang, Cheng Chen, Sharon Kam, Mark C. Wilkes, Hee-Don Chae, Kunju J. Sridhar, Peter L. Greenberg, Bertil Glader, Anupama Narla, Shuo Lin, Kathleen M. Sakamoto
Publikováno v:
Blood Advances, Vol 3, Iss 18, Pp 2751-2763 (2019)
The del(5q) myelodysplastic syndrome (MDS) is a distinct subtype of MDS, associated with deletion of the ribosomal protein S14 (RPS14) gene that results in macrocytic anemia. This study sought to identify novel targets for the treatment of patients w
Externí odkaz:
https://doaj.org/article/f293d06ad8ca4576845be250edd62e69
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 726 (2021)
Ribosomal S6 Kinases (RSKs) are a group of serine/threonine kinases that function downstream of the Ras/Raf/MEK/ERK signaling pathway. Four RSK isoforms are directly activated by ERK1/2 in response to extracellular stimuli including growth factors, h
Externí odkaz:
https://doaj.org/article/81757393bb6e4093baad2b7b8258b3a6
Autor:
Mark C. Wilkes, Vanessa Scanlon, Aya Shibuya, Alma-Martina Cepika, Ascia Eskin, Zugen Chen, Anupama Narla, Bert Glader, Maria Grazia Roncarolo, Stanley F. Nelson, Kathleen M. Sakamoto
Publikováno v:
Experimental Hematology. 111:66-78
Diamond-Blackfan Anemia (DBA) is an inherited bone marrow failure syndrome that is associated with anemia, congenital anomalies, and cancer predisposition. It is categorized as a ribosomopathy, because more than 80% or patients have haploinsufficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c7598c5921a6fb05add5295d61b8a1
https://doi.org/10.1016/j.exphem.2022.04.005
https://doi.org/10.1016/j.exphem.2022.04.005
Autor:
Kathleen M. Sakamoto, Keith B. Glaser, Michael C. Heinrich, Diana Griffith, Ajia Presnell, Xiaolin Tan, Elliot M. Landaw, Joan P. Zape, Jenny E. Hernandez-Davies
Supplementary Figure 3 from The Multitargeted Receptor Tyrosine Kinase Inhibitor Linifanib (ABT-869) Induces Apoptosis through an Akt and Glycogen Synthase Kinase 3β–Dependent Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a7ee63525783ac9a81acbdd140aaf0
https://doi.org/10.1158/1535-7163.22496235.v1
https://doi.org/10.1158/1535-7163.22496235.v1
