Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kathleen M Gajewski"'
Autor:
Kathleen M Gajewski, Robert A Schulz
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10713 (2010)
The zinc finger protein CF2 is a characterized activator of muscle structural genes in the body wall muscles of the Drosophila larva. To investigate the function of CF2 in the indirect flight muscle (IFM), we examined the phenotypes of flies bearing
Externí odkaz:
https://doaj.org/article/e58114005bc84c90b0af85adc0eac255
Autor:
Leticia Sansores-Garcia, Kathleen M Gajewski, Robert Andrew Mills, Leen Van Huffel, Mardelle Atkins, Violaine Mottier-Pavie, Jana Mach, Weronika Kowalczyk, Jun Xie, Georg Halder, Gordon B. Mills
Publikováno v:
Proceedings of the National Academy of Sciences. 115:10684-10689
The Hippo tumor-suppressor pathway regulates organ growth, cell proliferation, and stem cell biology. Defects in Hippo signaling and hyperactivation of its downstream effectors-Yorkie (Yki) in Drosophila and YAP/TAZ in mammals-result in progenitor ce
Autor:
Clayton M. Morrison, Fisun Hamaratoglu, Chunyao Tao, Georg Halder, Leticia Sansores-Garcia, Kathleen M Gajewski
Publikováno v:
Journal of Cell Science. 122:2351-2359
The Hippo tumor-suppressor pathway controls tissue growth in Drosophila and mammals by regulating cell proliferation and apoptosis. The Hippo pathway includes the Fat cadherin, a transmembrane protein, which acts upstream of several other components
Publikováno v:
Differentiation. 75:166-174
U-shaped is a zinc finger protein that functions predominantly as a negative transcriptional regulator of cell fate determination during Drosophila development. In the early stages of dorsal vessel formation, the protein acts to control cardioblast s
Publikováno v:
Molecular and Cellular Biology. 25:4200-4210
Early heart development in Drosophila and vertebrates involves the specification of cardiac precursor cells within paired progenitor fields, followed by their movement into a linear heart tube structure. The latter process requires coordinated cell i
Publikováno v:
Seminars in Cell & Developmental Biology. 16:107-116
GATA transcription factors comprise an evolutionarily conserved family of proteins that function in the specification and differentiation of various cell types during animal development. In this review, we examine current knowledge of the structure,
Autor:
Kathleen M Gajewski, Anh Dang, Qian Zhang, Robert A. Schulz, Nancy Fossett, Young Ho Kim, Yongsok Kim, Cheol Yong Choi
Publikováno v:
Developmental Biology. 233:425-436
During Drosophila embryogenesis, the homeobox gene tinman is expressed in the dorsal mesoderm where it functions in the specification of precursor cells of the heart, visceral, and dorsal body wall muscles. The GATA factor gene pannier is similarly e
Publikováno v:
Development. 127:559-572
bicaudal was the first Drosophila mutation identified as producing mirror-image pattern duplications along the anteroposterior axis of the embryo. However the mutation has been little studied due to its low penetrance and suppressibility. We undertoo
Publikováno v:
genesis. 28:36-43
Although often viewed as a simple pulsating tube, the Drosophila dorsal vessel is intricate in terms of its structure, cell types, and patterns of gene expression. Two nonidentical groups of cardial cells are observed in segments of the heart based o
Publikováno v:
The EMBO Journal. 16:515-522
The NK-type homeobox gene tinman and the MADS box gene D-mef2 encode transcription factors required for the development and differentiation of the Drosophila heart, and closely related genes regulate cardiogenesis in vertebrates. Genetic analyses ind