Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kathleen M C Sullivan"'
Autor:
Kathleen M C Sullivan, Marta Vilalta, Linda S Ertl, Yu Wang, Carolyn Dunlap, Karen Ebsworth, Bin N Zhao, Shijie Li, Yibin Zeng, Zhenhua Miao, Pingchen Fan, Venkat Mali, Christopher Lange, Darren McMurtrie, Ju Yang, Rebecca Lui, Ryan Scamp, Vicky Chhina, Alice Kumamoto, Simon Yau, Ton Dang, Ashton Easterday, Shirley Liu, Shichang Miao, Israel Charo, Thomas J Schall, Penglie Zhang
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286724 (2023)
The interaction of PD-L1 with PD-1 is a major immune checkpoint that limits effector T cell function against cancer cells; monoclonal antibodies that block this pathway have been approved in multiple tumor indications. As a next generation therapy, s
Externí odkaz:
https://doaj.org/article/a53419583b96441186b367f58673ff4f
Publikováno v:
Genetics. 165:1255-1268
We have studied lethal mutations in the single calmodulin gene (Cam) of Drosophila to gain insight into the in vivo functions of this important calcium sensor. As a result of maternal calmodulin (CaM) in the mature egg, lethality is delayed until the
Autor:
Gerald M. Rubin, Kathleen M C Sullivan
Publikováno v:
Genetics. 161:183-193
Calcineurin is a Ca2+-calmodulin-activated, Ser-Thr protein phosphatase that is essential for the translation of Ca2+ signals into changes in cell function and development. We carried out a dominant modifier screen in the Drosophila eye using an acti
Publikováno v:
Proceedings of the National Academy of Sciences. 92:8611-8615
Inositol 1,4,5-trisphosphate (IP3) receptors are ligand-gated channels that release intracellular Ca2+ stores in response to the second messenger, IP3. We investigated the potential role of IP3 receptors during nuclear envelope assembly in vitro, usi
We have investigated the role of the ryanodine receptor in Drosophila development by using pharmacological and genetic approaches. We identified a P element insertion in the Drosophila ryanodine receptor gene, Ryanodine receptor 44F ( Ryr ), and used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9762fe3f7113556266ee194ec6129e2
https://europepmc.org/articles/PMC18538/
https://europepmc.org/articles/PMC18538/
Publikováno v:
The Cell Cycle ISBN: 9781461360278
At the onset of mitosis in higher eukaryotes the nuclear envelope, ER, and Golgi complex are partially or completely converted to small vesicles. After mitosis, these biochemically distinct vesicles must fuse selectively to reassemble each organelle.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27069f825d2c8c1c8907c6fcd0671e18
https://doi.org/10.1007/978-1-4615-2421-2_23
https://doi.org/10.1007/978-1-4615-2421-2_23
Publikováno v:
Cell. 73(7)
We studied the fusion of nuclear vesicles bound to chromatin in Xenopus egg extracts. Fusion was inhibited by 5 mM BAPTA, a Ca2+ buffer that suppresses cytosolic [Ca2+] gradients. The BAPTA-inhibited step in fusion was biochemically distinct from, an