Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kathleen M, Woods Ignatoski"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 8, Pp 788-798 (2005)
To better underst, the mechanisms of transformation by the oncogene HER-2, we transduced the human mammary epithelial (HME) cell line MCF-10A with HER-2, developed a cell line that appeared to moderately overexpress HER-2. These MCF-10HER-2 cells wer
Externí odkaz:
https://doaj.org/article/fa7d3a1292b446a58816127c7e7f8354
Autor:
Kathleen M. Woods Ignatoski, Navdeep K. Grewal, Sonja Markwart, Donna L. Livant, Stephen P. Ethier
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 2, Pp 128-134 (2003)
We have previously shown that human breast cancer cells that overexpress erbB-2 are growth factorindependent. In order to test the contribution of erbB2 to this and other transformed phenotypes without the genetic instability of cancer cells, erbB-2
Externí odkaz:
https://doaj.org/article/f6b5fa36f950403288dee93d2ebec07c
Autor:
Venil N. Sumantran, David S. Lee, Kathleen M. Woods Ignatoski, Stephen P. Ethiert, Max S. Wicha
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 2, Iss 3, Pp 251-260 (2000)
Oncogenes which drive the cell cycle, such as c-myc, can sensitize cells to apoptosis. This suggests the possibility that the expression of genes such as bcl-2 or bcl-xL is required to inhibit apoptosis induced by oncogene expression. We hypothesized
Externí odkaz:
https://doaj.org/article/bfacac77b498404c8dd512cebcad16d3
Publikováno v:
BioTechniques, Vol 20, Iss 5, Pp 794-796 (1996)
Externí odkaz:
https://doaj.org/article/d167b80cf6a94dec9e31ccbf49954c7d
Autor:
Yongjia Feng, Farokh R. Demehri, Kathleen M. Woods Ignatoski, Matthew W. Ralls, Daniel H. Teitelbaum
Publikováno v:
Surgery. 157:732-742
To investigate the effect of nutrient withdrawal on human intestinal epithelial barrier function (EBF). We hypothesized that unfed mucosa results in decreased EBF. This was tested in a series of surgical small intestinal resection specimens.Small bow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7e40aba9e98eff41265088c62d27e6
https://doi.org/10.1016/j.surg.2014.12.004
https://doi.org/10.1016/j.surg.2014.12.004
Autor:
Stephanie Daignault, Nader Tawakkol, Hasan Korkaya, Nallasivam Palanisamy, Fayaz Malik, Ahmed A. Quraishi, Daniel F. Hayes, Kathleen M. Woods Ignatoski, Max S. Wicha, Tom Bersano-Begey, Tahra Luther, Christopher L. Hall, Scott J. Dawsey, Suthinee Ithimakin, Whitney A. Chadwick, Amber Heath, Mark L. Day, Dafydd G. Thomas, Shawn G. Clouthier, April Davis, Qin Zen, Kathleen C. Day, Celina G. Kleer
Publikováno v:
Cancer Research. 73:1635-1646
Although current breast cancer treatment guidelines limit the use of HER2-blocking agents to tumors with HER2 gene amplification, recent retrospective analyses suggest that a wider group of patients may benefit from this therapy. Using breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f3dd6e36ec8f8e4bbd8b5f2910c7dd
https://doi.org/10.1158/0008-5472.can-12-3349
https://doi.org/10.1158/0008-5472.can-12-3349
Autor:
Dafydd G. Thomas, Mark L. Day, Alyssa Paul, Nallasivam Palanisamy, Sunitha Nagrath, Andrew Chou, Scott J. Dawsey, Rajal B. Shah, Kathleen M. Woods Ignatoski, Molly Kozminsky, Guadalupe Lorenzatti Hiles, Evan T. Keller, Lakshmi P. Kunja, Chris Hall, Stephanie Daignault-Newton, Kathleen C. Day, Steven James Wilson, Todd M. Morgan, Layla El-Sawy, Luke J. Broses
Publikováno v:
Cancer research. 77(1)
Activation of the EGF receptors EGFR (ErbB1) and HER2 (ErbB2) drives the progression of multiple cancer types through complex mechanisms that are still not fully understood. In this study, we report that HER2 expression is elevated in bone metastases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a83d3509b7a7cfe0c6638fc425b1b6
https://pubmed.ncbi.nlm.nih.gov/27843146
https://pubmed.ncbi.nlm.nih.gov/27843146
Publikováno v:
Tissue Engineering Part C: Methods. 17:1051-1059
Replacement of a diseased organ with an autologously derived tissue is an ideal therapy for some medical problems. However, it is difficult to recreate many adult human tissues in vitro due to the functionally necessary architecture of most organs an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca512887fc8061cce7df02d70e5d3ed5
https://doi.org/10.1089/ten.tec.2011.0170
https://doi.org/10.1089/ten.tec.2011.0170
Autor:
Hallie J. Kintner, Amanda Bucheit, Christopher G. Wood, Jason R. Gee, Monica Liebert, H. Barton Grossman, David L. Morris, Lakshmi P. Kunju, Christopher Tallman, Stephanie Tseng-Rogenski, Joshua M. Evron, Kathleen M. Woods Ignatoski, Cheryl T. Lee
Publikováno v:
The American Journal of Pathology. 176:1462-1468
Prostaglandin E2, which is known to contribute to cancer progression, is inactivated by the catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase (PGDH), which has tumor-suppressor activity in lung, colon, breast, and gastric cancers. Therefore, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f336ae966950730b81046b71c9583add
https://doi.org/10.2353/ajpath.2010.090875
https://doi.org/10.2353/ajpath.2010.090875
Publikováno v:
The Prostate. 69:528-537
BACKGROUND. Bone metastasis occurs frequently in advanced prostate cancer (PCa) patients; however, it is not known why this happens. The epidermal growth factor receptor (EGFR) ligand EGF is available to early stage PCa; whereas, TGF-a is available w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3884edf64706f1f9d8972cbe71ada05
https://doi.org/10.1002/pros.20903
https://doi.org/10.1002/pros.20903