Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Kathleen M, Shannon"'
Autor:
Madelyn C. Houser, W. Michael Caudle, Jianjun Chang, George T. Kannarkat, Yuan Yang, Sean D. Kelly, Danielle Oliver, Valerie Joers, Kathleen M. Shannon, Ali Keshavarzian, Malú Gámez Tansey
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-23 (2021)
Abstract Background The etiology of sporadic Parkinson’s disease (PD) remains uncertain, but genetic, epidemiological, and physiological overlap between PD and inflammatory bowel disease suggests that gut inflammation could promote dysfunction of d
Externí odkaz:
https://doaj.org/article/8e618e46d41448b989d12a0fc10bd262
Autor:
Kathleen M. Shannon
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
The etiology of Parkinson's disease (PD) is unknown, but evidence is increasing that there is a prominent inflammatory component to the illness. Epidemiological, genetic, and preclinical evidence support a role for gut-derived sterile inflammation. P
Externí odkaz:
https://doaj.org/article/6b26fbe374044835bb1f868e6ab65376
Autor:
Hemraj B. Dodiya, Christopher B. Forsyth, Robin M. Voigt, Phillip A. Engen, Jinal Patel, Maliha Shaikh, Stefan J. Green, Ankur Naqib, Avik Roy, Jeffrey H. Kordower, Kalipada Pahan, Kathleen M. Shannon, Ali Keshavarzian
Publikováno v:
Neurobiology of Disease, Vol 135, Iss , Pp 104352- (2020)
Recent evidence provides support for involvement of the microbiota-gut-brain axis in Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory intestinal milieu, due to intestinal hyper-permeability and/or microbial dysbiosis, initiat
Externí odkaz:
https://doaj.org/article/85f55182187343e693ad6b2eebc87215
Autor:
Kathleen M. Shannon
Publikováno v:
CNS Drugs. 34:219-228
Huntington's disease is a dominantly inherited neurodegenerative disease caused by an unstable expanded trinucleotide repeat at the short end of the fourth chromosome. Central nervous system pathology begins in the striatum, eventually affecting the
Autor:
Laura Buyan Dent, Kathleen M. Shannon
Publikováno v:
Movement Disorder Emergencies ISBN: 9783030758974
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f699daee889aefe0c1b505d5237b75f
https://doi.org/10.1007/978-3-030-75898-1_29
https://doi.org/10.1007/978-3-030-75898-1_29
Autor:
Danielle Oliver, Madelyn C. Houser, Kathleen M. Shannon, Valerie Joers, Jianjun Chang, Malú G. Tansey, Ali Keshavarzian, W. Michael Caudle, Sean D. Kelly, George T. Kannarkat, Yuan Yang
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-23 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-23 (2021)
Background The etiology of sporadic Parkinson’s disease (PD) remains uncertain, but genetic, epidemiological, and physiological overlap between PD and inflammatory bowel disease suggests that gut inflammation could promote dysfunction of dopamine-p
Publikováno v:
Deep Brain Stimulation
Huntington disease (HD) is a progressive neurodegenerative disorder characterized by chorea and cognitive and psychiatric disturbances. Dystonia is also a common symptom, and a recent case study points toward 50% of HD patients having truncal dystoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9b38eb32fc3c293f38f8d24761c2585
https://doi.org/10.1093/med/9780190647209.003.0040
https://doi.org/10.1093/med/9780190647209.003.0040
Autor:
Phillip A. Engen, Ali Keshavarzian, Ankur Naqib, Avik Roy, Jeffrey H. Kordower, Robin M. Voigt, Christopher B. Forsyth, Jinal Patel, Hemraj B. Dodiya, Kathleen M. Shannon, Maliha Shaikh, Stefan J. Green, Kalipada Pahan
Publikováno v:
Neurobiology of Disease, Vol 135, Iss, Pp 104352-(2020)
Recent evidence provides support for involvement of the microbiota-gut-brain axis in Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory intestinal milieu, due to intestinal hyper-permeability and/or microbial dysbiosis, initiat
Autor:
Christopher B Forsyth, Kathleen M Shannon, Jeffrey H Kordower, Robin M Voigt, Maliha Shaikh, Jean A Jaglin, Jacob D Estes, Hemraj B Dodiya, Ali Keshavarzian
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28032 (2011)
Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging. The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main component is alpha-synuclein protein. The finding of these Lewy bodies in the
Externí odkaz:
https://doaj.org/article/8ca2c8dad6624dddb1a6f791ddea07aa
Publikováno v:
Cell Transplantation, Vol 16 (2007)
Huntington's disease (HD) is a devastating neurodegenerative disorder that occurs in patients with a mutation in the huntingtin or IT15 gene. Patients are plagued by early cognitive signs, motor deficits, and psychiatric disturbances. Symptoms are at
Externí odkaz:
https://doaj.org/article/f94320772dcc40c9a25ecb248725e335