Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kathleen Last-Barney"'
Autor:
Vincent J. Merluzzi, Ronald B. Faanes, Kathleen Last-Barney, Deborah D. Jeanfavre, Eugene J. McNally, Steven D. Marlin, Carol Cahill
Publikováno v:
Journal of Virological Methods. 35:255-264
Soluble intercellular adhesion molecule-1 (sICAM-1) was shown to be the receptor for the major subgroup of rhinoviruses. It was demonstrated that this molecule can inhibit the binding and subsequent infection of target cells by rhinoviruses belonging
Autor:
Gary O. Caviness, Mark E. Labadia, Maurice M. Morelock, Joseph R. Woska, Deborah D. Jeanfavre, Kathleen Last-Barney, Patricia Giblin
Publikováno v:
Biochemical pharmacology. 74(1)
Molecular K(d) and k(off) parameters are often used to define the molecular potency of drugs. These constants, however, are determined on purified target proteins, and their relationship to in vivo binding phenomena is poorly understood. Herein, we r
Autor:
Robert Rothlein, Maret Panzenbeck, Elizabeth Mainolfi, Terence A. Kelly, Rachel R. Kroe, Gary O. Caviness, Kathleen Last-Barney, Joseph R. Woska, Deborah D. Jeanfavre, Patricia Giblin, Steven E. Fogal, Patricia L. Reilly, Takashi Kei Kishimoto
Publikováno v:
Journal of immunological methods. 277(1-2)
The beta(2) integrin LFA-1 (CD11a/CD18) is a leukocyte-specific adhesion molecule that mediates leukocyte extravasation, antigen presentation, and T-cell-mediated cytolysis through its interaction with its counter-receptors, ICAM-1, ICAM-2, and ICAM-
Autor:
Walter Davidson, Jerry L. Hopkins, Deborah D. Jeanfavre, Kathleen Last Barney, Terence A. Kelly, Christine A. Grygon
Publikováno v:
Journal of the American Society for Mass Spectrometry. 14(1)
The allosteric inhibition of the lymphocyte function associated antigen-1/intercellullar adhesion molecule (LFA-1/ICAM-1) interaction, by a class of small molecules, is characterized by a battery of mass spectrometric techniques. Binding of hydantoin
Autor:
Jerry L. Hopkins, Deborah D. Jeanfavre, James M. Stevenson, Kathleen Last-Barney, Chungeng Qian, Leah L. Frye, Terence A. Kelly, Christine A. Grygon, Renee Zindell, Mario G. Cardozo, Liang Tong, Walter Davidson, Susan Pav
Publikováno v:
Journal of the American Chemical Society. 123(24)
The binding site on the lymphocyte function-associated antigen-1 (LFA-1) of a class of hydantoin-based antagonists of leukocyte cell adhesion has been identified. This site resides in the inserted-domain (I-domain) of the CD11a chain at a location th
Autor:
Deborah D. Jeanfavre, K Pal, Eugene J. McNally, C Cahill-Feehan, Vincent J. Merluzzi, Steven D. Marlin, Kathleen Last-Barney
Publikováno v:
Antimicrobial agents and chemotherapy. 37(8)
A method utilizing immobilized major group rhinoviruses and biotinylated soluble intercellular adhesion molecule 1 has been developed for the detection of capsid binders. Binding measurements indicate a loss in relative affinity of biotinylated solub
Autor:
Robert Rothlein, Chester Wood, Ronald B. Faanes, Carol D. Stearns, Kathleen Last-Barney, Vincent J. Merluzzi
Publikováno v:
Leukocyte Adhesion Molecules ISBN: 9781461279273
Cell-cell adhesion is believed to be an integral event in the development of effective immunological responses. A family of molecules has been described which mediate leukocyte cell-cell and cell-substrate adhesions and are necessary for cell migrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb68dbfc9651460ad5f0e5d1ede1c31
https://doi.org/10.1007/978-1-4612-3234-6_20
https://doi.org/10.1007/978-1-4612-3234-6_20
Publikováno v:
International Journal of Immunopharmacology. 7:31-39
Experimental and clinical systems have been developed to analyze both the in vitro and in vivo effects of highly purified interleukin 2 (IL2) as a potential therapeutic adjunct for neoplasia, immunodeficiency and infectious disease. Animal models, cl
Autor:
Kathleen Last-Barney, Jeffrey H. Greenbaum, John M. Budinger, A. Giner-Sorolla, Lucy M. Anderson
Publikováno v:
Cancer Letters. 6:79-82
N6(Methylnitroso) adenosine (M6(NO)Ado) is found readily under acidic conditions by the interaction of nitrite with 6-methyladenosine, a naturally-occurring nucleoside. Swiss mice were treated with M6(NO)Ado by injection (40 mg/kg each treatment) tra
Autor:
Jeffrey H. Greenbaum, A. Giner-Sorolla, John M. Budinger, Kathleen Last-Barney, Lucy M. Anderson
Publikováno v:
Food and Cosmetics Toxicology. 18:81-83
The nitroso derivatives of two widely used psychotropic drugs, chlordiazepoxide and methylphenidate, were each administered in the drinking-water of (C57BL/6 × BALB/c) F 1 mice at concentrations of 50 and 100 mg/litre, respectively. The mice were tr