Zobrazeno 1 - 10
of 565
pro vyhledávání: '"Kathleen I. Pritchard"'
Autor:
John Hilton, Karen Gelmon, Philippe L. Bedard, Dongsheng Tu, Hong Xu, Anna V. Tinker, Rachel Goodwin, Scott A. Laurie, Derek Jonker, Aaron R. Hansen, Zachary W. Veitch, Daniel J. Renouf, Linda Hagerman, Hongbo Lui, Bingshu Chen, Deb Kellar, Irene Li, Sung-Eun Lee, Takako Kono, Brian Y. C. Cheng, Damian Yap, Daniel Lai, Sean Beatty, John Soong, Kathleen I. Pritchard, Isabel Soria-Bretones, Eric Chen, Harriet Feilotter, Moira Rushton, Lesley Seymour, Samuel Aparicio, David W. Cescon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
G-quadruplex stabilizers, including CX-5461, exhibit synthetic lethality with loss of BRCA1/2 in preclinical models. Here the authors report the results of a phase I study of CX-5461 in patients with solid tumors enriched for DNA-repair deficiencies.
Externí odkaz:
https://doaj.org/article/ee095627571b4e258e1890f77d3d7597
Autor:
Phillip S. Blanchette, Melody Lam, Britney Le, Lucie Richard, Salimah Z. Shariff, Alexandra M. Ouédraogo, Kathleen I. Pritchard, Jacques Raphael, Ted Vandenberg, Ricardo Fernandes, Danielle N. Desautels, Kelvin K.W. Chan, Craig C. Earle
Publikováno v:
Breast, Vol 60, Iss , Pp 295-301 (2021)
Background: The use of endocrine therapy for early-stage breast cancer, particularly aromatase inhibitor therapy has been associated with an increased risk of osteoporosis and fracture in clinical trials. We sought to validate this observation in rea
Externí odkaz:
https://doaj.org/article/669ad70f8697435b982217ebf83fd6ed
Autor:
Liewei Wang, Krishna R. Kalari, Richard M. Weinshilboum, Matthew P. Goetz, Erin E. Carlson, Poulami Barman, Kathleen I. Pritchard, Vered Stearns, Yukihide Momozawa, Yoichi Furukawa, Michiaki Kubo, Bingshu E. Chen, Judith-Anne W. Chapman, Lois E. Shepherd, Paul E. Goss, Matthew J. Ellis, Fang Xie, James N. Ingle
Knockdown of MIR2052HG in ERα-negative cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e60369e891355256e787bc9d169412
https://doi.org/10.1158/0008-5472.22413239.v1
https://doi.org/10.1158/0008-5472.22413239.v1
Autor:
Torsten O. Nielsen, Charles M. Perou, Philip S. Bernard, Matthew J. Ellis, Joel S. Parker, Mark T.W. Ebbert, Carole Davis, Inge J. Stijleman, Sherri Davies, Kathleen I. Pritchard, Mark N. Levine, Lois E. Shepherd, Stephen K. Chia, Samuel Leung, Shan Jiang, Dongsheng Tu, K. David Voduc, Maggie C.U. Cheang
PDF file - 44K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdef29a39de8ebccd33401bfe5e6092
https://doi.org/10.1158/1078-0432.22443840
https://doi.org/10.1158/1078-0432.22443840
Autor:
Torsten O. Nielsen, Lois E. Shepherd, Kathleen I. Pritchard, Mark N. Levine, Vivien Bramwell, Dongxia Gao, Dongsheng Tu, Karama Asleh
Survival analysis showing the primary endpoint of disease-free survival for patients receiving tamoxifen (red lines) vs. placebo (black lines) in the MA.12 translational study cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dbf86e30d9ef44228ca516c4b170ac
https://doi.org/10.1158/1078-0432.22482417.v1
https://doi.org/10.1158/1078-0432.22482417.v1
Autor:
Torsten O. Nielsen, Matthew J. Ellis, Charles M. Perou, Philip S. Bernard, Joel S. Parker, Kathleen I. Pritchard, Karen Ung, Samuel Leung, Elaine Mardis, Tammi Vickery, Shan Jiang, Lois E. Shepherd, Dongsheng Tu, Vivien H. Bramwell, Stephen K. Chia
PDF file, 68KB, Supplemental Table 1: Intrinsic subtype definitions by immunohistochemistry. Supplemental Table 2: C-Index for Risk-of-Relapse (ROR) Scores.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56185a9212a8a2018d58a5bce093594b
https://doi.org/10.1158/1078-0432.22445478.v1
https://doi.org/10.1158/1078-0432.22445478.v1
Supplementary Data from Preferential Killing of Breast Tumor Initiating Cells by N,N-Diethyl-2-[4-(Phenylmethyl)Phenoxy]Ethanamine/Tesmilifene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86124d398dda33555ef010bc5317f7a6
https://doi.org/10.1158/1078-0432.22439652
https://doi.org/10.1158/1078-0432.22439652
Autor:
Torsten O. Nielsen, Charles M. Perou, Philip S. Bernard, Matthew J. Ellis, Joel S. Parker, Mark T.W. Ebbert, Carole Davis, Inge J. Stijleman, Sherri Davies, Kathleen I. Pritchard, Mark N. Levine, Lois E. Shepherd, Stephen K. Chia, Samuel Leung, Shan Jiang, Dongsheng Tu, K. David Voduc, Maggie C.U. Cheang
PDF file - 49K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6523fcc0f7ce1bf27d4468d2022c36
https://doi.org/10.1158/1078-0432.22443843
https://doi.org/10.1158/1078-0432.22443843
Autor:
Torsten O. Nielsen, Lois E. Shepherd, Kathleen I. Pritchard, Mark N. Levine, Vivien Bramwell, Dongxia Gao, Dongsheng Tu, Karama Asleh
Purpose:Accurate IHC biomarkers incorporating nestin positivity or inositol polyphosphate-4-phosphate (INPP4B) loss have recently been optimized to identify the basal-like intrinsic breast cancer subtype regardless of estrogen, progesterone, or Her2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b5588e8e62cd0d5a9205c0a7c07f59
https://doi.org/10.1158/1078-0432.c.6530922
https://doi.org/10.1158/1078-0432.c.6530922
Autor:
Torsten O. Nielsen, Matthew J. Ellis, Charles M. Perou, Philip S. Bernard, Joel S. Parker, Kathleen I. Pritchard, Karen Ung, Samuel Leung, Elaine Mardis, Tammi Vickery, Shan Jiang, Lois E. Shepherd, Dongsheng Tu, Vivien H. Bramwell, Stephen K. Chia
PDF file, 125KB, Supplemental Figure 1: REMARK Diagram for MA.12 Trial and Biospecimens Supplemental Figure 2: Forest plot for Disease free Survival across various Classifiers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2673c3fa992d2aa8f0bb23402c00b3
https://doi.org/10.1158/1078-0432.22445481.v1
https://doi.org/10.1158/1078-0432.22445481.v1