Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kathleen Hornbacker"'
Autor:
Thomas Yang Sun, Lan Zhao, Paul Van Hummelen, Brock Martin, Kathleen Hornbacker, HoJoon Lee, Li C Xia, Sukhmani K Padda, Hanlee P Ji, Pamela Kunz
Publikováno v:
Endocr Relat Cancer
High-grade (grade 3) neuroendocrine neoplasms (G3 NENs) have poor survival outcomes. From a clinical standpoint, G3 NENs are usually grouped regardless of primary site and treated similarly. Little is known regarding the underlying genomics of these
Autor:
Patrick W. McGarrah, Christoph R. Becker, Rujuta Gadgil, Jennifer A. Chan, Pamela L. Kunz, Nitya Raj, Emily K. Bergsland, David Chan, Alia Thawer, Virginia Kelly, Linda Wu, Diane Lauren Reidy, Kathleen Hornbacker, Thorvardur R. Halfdanarson, Simron Singh, Julia Whitman
Publikováno v:
Oncologist
Background Grade 3 gastroenteropancreatic neuroendocrine neoplasms (G3 GEPNENs) are often aggressive, and the optimal treatment is unclear for this subgroup of neuroendocrine neoplasms (NENs). Temozolomide (TEM)-based regimens have been increasingly
Autor:
Theresa Wittenberg, Pamela L. Kunz, Kathleen Hornbacker, Hussein A. Assi, Shagufta Shaheen, Robyn Silberman
Publikováno v:
Pancreas. 50:890-894
Peptide receptor radionuclide therapy (PRRT) is a treatment option for somatostatin receptor-positive, unresectable or metastatic neuroendocrine tumors (NETs). Despite high disease control rates seen with PRRT, a subset of the NET population seems to
Autor:
Jalen Benson, Natalie S. Lui, Mythili P. Pathipati, Thomas K. Yohannan, Kathleen Hornbacker, Lu Tian, Sukhmani K. Padda, Pamela L. Kunz, Gerald J. Berry
Publikováno v:
Lung Cancer
Well-differentiated lung neuroendocrine tumors (NETs), also known as typical and atypical carcinoids, have a decreased incidence of lymph node (LN) and distant metastases compared to poorly differentiated lung NETs. We aimed to (i) examine the clinic
Autor:
Vandana Sundaram, Christine H. Lee, Kaisha N. Benjamin, Teri A. Longacre, Kathleen Hornbacker, Pamela L. Kunz, Allison Zemek, Aidan Van Vleck, Timothy M. Horton, Justin P. Annes
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Neuroendocrine neoplasms (NENs) are rare epithelial tumors with heterogeneous and frequently unpredictable clinical behavior. Available biomarkers are insufficient to guide individual patient prognosis or therapy selection. Peptidylglycine α-amidati
Autor:
Pamela L. Kunz, Danielle S. Pancirer, Sukhmani K. Padda, Natalie S. Lui, Grace Hwang, Rishi Raj, Kathleen Hornbacker, Alberto Codima, Thomas Yang Sun
Publikováno v:
The European Respiratory Journal
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is considered a preinvasive lesion that may progress to carcinoid tumour [1]. Histologically, it is marked by a proliferation of neuroendocrine cells that is confined to the basem
Autor:
Natalie S. Lui, A. Codima, Danielle S. Pancirer, Kathleen Hornbacker, Thomas Yang Sun, Grace Hwang, Sukhmani K. Padda, Pamela L. Kunz, Rishi Raj
Publikováno v:
Journal of Thoracic Oncology. 16:S179
Autor:
Hojoon Lee, Thomas Yang Sun, Pamela L. Kunz, Hanlee P. Ji, Lan Zhao, Paul Van Hummelen, Brock A. Martin, Charlie Xia, Kathleen Hornbacker
Publikováno v:
Journal of Clinical Oncology. 38:624-624
624 Background: Grade 3 neuroendocrine neoplasms (G3 NENs), if poorly differentiated, have a median survival of only 10-19 months. Little is known regarding their underlying genomics. Methods: We applied multiomics analysis to 46 cases of G3 NEN that
Autor:
Alia Thawer, Emily K. Bergsland, Pamela L. Kunz, Kathleen Hornbacker, Linda Wu, Thorvardur R. Halfdanarson, Rujuta Gadgil, Virginia Kelly, Nitya Raj, Diane Lauren Reidy, Patrick W. McGarrah, David Chan, Simron Singh, Jennifer A. Chan, Julia Whitman
Publikováno v:
Journal of Clinical Oncology. 37:321-321
321 Background: G3 NENs are aggressive, and optimal systemic treatment is unclear. Temozolomide (TEM)-based regimens have been used to treat grade 1-2 NETs, but their efficacy in G3 NENs (Ki-67 > 20%) remains undetermined. Aims: To assess the clinica