Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kathleen H. Rubins"'
Autor:
Alexa Wnorowski, Arun Sharma, Haodong Chen, Haodi Wu, Ning-Yi Shao, Nazish Sayed, Chun Liu, Stefanie Countryman, Louis S. Stodieck, Kathleen H. Rubins, Sean M. Wu, Peter H.U. Lee, Joseph C. Wu
Publikováno v:
Stem Cell Reports, Vol 13, Iss 6, Pp 960-969 (2019)
Summary: With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function. We utilized human induced pluripotent stem cell-derived cardiomyocyt
Externí odkaz:
https://doaj.org/article/1a462e3bc42446aa949cd8d4fa18e096
Autor:
Haodong Chen, Sean M. Wu, Alexa Wnorowski, Arun Sharma, Ning-Yi Shao, Haodi Wu, Kathleen H. Rubins, Jared M. Churko, Stefanie Countryman, Elena Matsa, Peter H.U. Lee, Joseph C. Wu
Publikováno v:
Circulation Research. 123
With extended stays aboard the International Space Station (ISS) becoming commonplace as humanity prepares for exploration-class space missions, the need to better understand the effects of cardiac function during spaceflight is critical. However, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46b207e91024202aab20c8289d41ecde
https://doi.org/10.1161/res.123.suppl_1.379
https://doi.org/10.1161/res.123.suppl_1.379
Autor:
Rebecca S. Blue, Helmut G. Katzgraber, Kathleen H. Rubins, Ann R. Kennedy, Serena M. Auñón-Chancellor, Keith A. Cengel, Jeffery C. Chancellor
Publikováno v:
NPJ Microgravity
npj Microgravity, Vol 4, Iss 1, Pp 1-11 (2018)
npj Microgravity, Vol 4, Iss 1, Pp 1-11 (2018)
Despite years of research, understanding of the space radiation environment and the risk it poses to long-duration astronauts remains limited. There is a disparity between research results and observed empirical effects seen in human astronaut crews,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44d93be88622a5adde04caed8656294
Autor:
Douglas J. Botkin, Sarah E. Stahl, Noah Alexander, Kristen K. John, Sarah L. Castro-Wallace, Guixia Yu, Jason P. Dworkin, Timothy A. Stephenson, Charles Y. Chiu, Sissel Juul, Christopher E. Mason, Kathleen H. Rubins, David J. Smith, Daniel J. Turner, Mark L. Lupisella, Fernando Izquierdo, Sneha Somasekar, Alexa B. R. McIntyre, Doug Stryke, Aaron S. Burton, Scot Federman
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific reports, vol 7, iss 1
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific reports, vol 7, iss 1
The emergence of nanopore-based sequencers greatly expands the reach of sequencing into low-resource field environments, enabling in situ molecular analysis. In this work, we evaluated the performance of the MinION DNA sequencer (Oxford Nanopore Tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cabca0082224165adef4f0dfdac69be
https://doi.org/10.1101/077651
https://doi.org/10.1101/077651
Autor:
Sara A. Michie, Kathleen H. Rubins, Robert D. Schreriber, Hugh O. McDevitt, Qing Li, Baohui Xu
Publikováno v:
Proceedings of the National Academy of Sciences. 105:12439-12444
With the goal of identifying changes in gene expression in CD4 + T cells during the development of diabetes in the nonobese diabetic (NOD) mouse, we used DNA microarrays to analyze gene expression in CD4 + T cells from the pancreatic draining lymph n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a6ada0dcd39e2beab8878a5437ec55
https://doi.org/10.1073/pnas.0806439105
https://doi.org/10.1073/pnas.0806439105
Publikováno v:
Current Opinion in Microbiology
DNA microarray-based gene transcript-profiling of the responses of primates to infection has begun to yield new insights into host-pathogen interactions; this approach, however, remains plagued by challenges and complexities that have yet to be adequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64e53745c0e10550c07e3ae46abec72
http://europepmc.org/articles/PMC7108404
http://europepmc.org/articles/PMC7108404
Autor:
James W. LeDuc, Art B. Owen, Thomas W. Geisbert, John W. Huggins, Kathleen H. Rubins, Patrick O. Brown, Lisa E. Hensley, Peter B. Jahrling, David A. Relman, Adeline R. Whitney
Publikováno v:
Proceedings of the National Academy of Sciences. 101:15190-15195
Smallpox has played an unparalleled role in human history and remains a significant potential threat to public health. Despite the historical significance of this disease, we know little about the underlying pathophysiology or the virulence mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa47a0aca2c6faceae78c744417388ba
https://doi.org/10.1073/pnas.0405759101
https://doi.org/10.1073/pnas.0405759101
Autor:
Mark J. Martinez, John W. Huggins, James W. LeDuc, Kathleen H. Rubins, David A. Relman, Lisa E. Hensley, Peter B. Jahrling
Publikováno v:
Proceedings of the National Academy of Sciences. 101:15196-15200
Smallpox virus (variola) poses a significant threat as an agent of bioterrorism. To mitigate this risk, antiviral drugs and an improved vaccine are urgently needed. Satisfactory demonstration of protective efficacy against authentic variola will requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11953f3fef08610099463d2744d35afe
https://doi.org/10.1073/pnas.0405954101
https://doi.org/10.1073/pnas.0405954101
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15615 (2011)
PLoS ONE
PLoS ONE
Poxviruses use an arsenal of molecular weapons to evade detection and disarm host immune responses. We used DNA microarrays to investigate the gene expression responses to infection by monkeypox virus (MPV), an emerging human pathogen, and Vaccinia v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ad1f88d11d6b60eb6ed1343cedc1d6
http://europepmc.org/articles/PMC3022624?pdf=render
http://europepmc.org/articles/PMC3022624?pdf=render
Autor:
Stephen J. Popper, Michael Levin, David A. Relman, Michael J. Griffiths, Kathleen H. Rubins, Patrick O. Brown, Simon J. Waddell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 3, p e9753 (2010)
PLoS ONE, Vol 5, Iss 3, p e9753 (2010)
Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and indirect effects, and of homotypic and heterotypic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2895ffdb413b3201a5aec77317459b59
http://sro.sussex.ac.uk/id/eprint/7064/1/journal.pone.0009753.pdf
http://sro.sussex.ac.uk/id/eprint/7064/1/journal.pone.0009753.pdf