Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kathleen G Banks"'
Autor:
Charles N de Leeuw, Frank M Dyka, Sanford L Boye, Stéphanie Laprise, Michelle Zhou, Alice Y Chou, Lisa Borretta, Simone C McInerny, Kathleen G Banks, Elodie Portales-Casamar, Magdalena I Swanson, Cletus A D'Souza, Shannon E Boye, Steven JM Jones, Robert A Holt, Daniel Goldowitz, William W Hauswirth, Wyeth W Wasserman, Elizabeth M Simpson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Critical for human gene therapy is the availability of small promoters tools to drive gene expression in a highly specific and reproducible manner. We tackled this challenge by developing human DNA MiniPromoters (MiniPs) using computational biology a
Externí odkaz:
https://doaj.org/article/a4992868fae84ac68f19247787a4fd6f
Autor:
Stéphanie Laprise, Elizabeth M. Simpson, Kathleen G. Banks, Allison M. Cotton, Carolyn J. Brown, Charles N. de Leeuw, Christine Yang, Andrea J. McLeod
Publikováno v:
Genetics
Regulatory sequences can influence the expression of flanking genes over long distances, and X chromosome inactivation is a classic example of cis-acting epigenetic gene regulation. Knock-ins directed to the Mus musculus Hprt locus offer a unique opp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f72bf333159cb32af72c89085af050
https://doi.org/10.1534/genetics.112.143743
https://doi.org/10.1534/genetics.112.143743
Autor:
Slavita Bohacec, Russell J. Bonaguro, David J. Arenillas, Steven J.M. Jones, Siaw H. Wong, Jean-François Schmouth, Elizabeth M. Simpson, Kathleen G. Banks, Marco A. Marra, Wyeth W. Wasserman, Yuanyun Xie, Ximena Corso-Díaz
Publikováno v:
BMC Genomics
Background Nr2e1 (nuclear receptor subfamily 2, group e, member 1) encodes a transcription factor important in neocortex development. Previous work has shown that nuclear receptors can have hundreds of target genes, and bind more than 300 co-interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b030431bc44c5582b517360b55b9bb9e
https://doi.org/10.1186/s12864-015-1770-3
https://doi.org/10.1186/s12864-015-1770-3
Autor:
Dita M. Rasper, Sophie Roy, Elizabeth M. Simpson, Donald W. Nicholson, Erich L. Grimm, Caroline Houde, Nathalie Coulombe, Kathleen G. Banks
Publikováno v:
The Journal of Neuroscience. 24:9977-9984
Caspase-3-deficient mice of the 129S1/SvImJ (129) strain show severe brain development defects resulting in brain overgrowth and perinatal lethality, whereas on the C57BL/6J (B6) background, these mice develop normally. We therefore sought to identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74832063ab2e031aad88ae9ecf70f7c
https://doi.org/10.1523/jneurosci.3356-04.2004
https://doi.org/10.1523/jneurosci.3356-04.2004
Publikováno v:
Mammalian Genome. 11:440-447
In mammals, during fetal development, the eyelids grow and flatten over the eyes and temporarily fuse closed. Failure of this normal developmental process in mice leads to the defect, open-eyelids-at-birth. Nearly all newborns of the GP/Bc strain, ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72782f5d070ad756f2241223c2ac976
https://doi.org/10.1007/s003350010084
https://doi.org/10.1007/s003350010084
Autor:
Wyeth W. Wasserman, Elizabeth M. Simpson, Anthony Mathelier, Kevin Gregory-Evans, Mauro Castellarin, Cheryl Y. Gregory-Evans, Jean-François Schmouth, Kathleen G. Banks, Robert A. Holt
Nr2e1 encodes a stem cell fate determinant of the mouse forebrain and retina. Abnormal regulation of this gene results in retinal, brain, and behavioral abnormalities in mice. However, little is known about the functionality of human NR2E1. We invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520858a88dbcf244364500fce69f5b5e
https://europepmc.org/articles/PMC3302440/
https://europepmc.org/articles/PMC3302440/
Autor:
Bibiana K. Y. Wong, Randy Glenn, Cletus D'Souza, Vik Chopra, Magdalena I. Swanson, Meifen Lu, Flora Liu, Douglas J. Swanson, Marko Milisavljevic, Diana L. Palmquist, Taryn G. Hearty, Jenna L. Turner, Jonathan S. Lim, Steven J.M. Jones, Debra L. Fulton, Erin K. Flynn, Wyeth W. Wasserman, Dan Goldowitz, Betty Palma, Sonia F. Black, David J. Arenillas, Steven Jiang, Jing M. Chen, Charles N. de Leeuw, Russell J. Bonaguro, Stéphanie Laprise, Kathleen G. Banks, Athena R. Ypsilanti, Jacek Mis, Mahsa Amirabbasi, Ivana Komljenovic, Katie O’Connor, Robert A. Holt, Nancy Y. Liao, Ying Chen, Russell F. Watkins, Stuart Lithwick, Shannan J. Ho Sui, Elodie Portales-Casamar, Richard Varhol, Bonny Tam, Jun Liu, Li Liu, Lisa Dreolini, Mauro Castellarin, Andrea J. McLeod, Amy Ticoll, Nazar Babyak, Kristi Hatakka, Elizabeth M. Simpson, Jason C. Y. Cheng, Gary M. Wilson, Siaw H. Wong, Erich Brauer, Jean-François Schmouth, Behzad Imanian, Melissa K. McConechy, Johar Ali, Shadi Khorasan-zadeh, Jenny Vermeulen, T. Roderick Docking, George S. Yang, Tony Wong, Tara Candido
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(38)
The Pleiades Promoter Project integrates genomewide bioinformatics with large-scale knockin mouse production and histological examination of expression patterns to develop MiniPromoters and related tools designed to study and treat the brain by direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b311c1674c9c1ac3c1eb5e4433c1a2d
https://pubmed.ncbi.nlm.nih.gov/21049577
https://pubmed.ncbi.nlm.nih.gov/21049577
Autor:
Russell J. Bonaguro, George S. Yang, L. Liu, C.N. de Leeuw, Douglas J. Swanson, Gary M. Wilson, Dan Goldowitz, Robert A. Holt, Lisa Dreolini, Kathleen G. Banks, Elizabeth M. Simpson
Publikováno v:
Genomics. 93(3)
We have engineered a set of useful tools that facilitate targeted single copy knock-in (KI) at the hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) locus. We employed fine scale mapping to delineate the precise breakpoint location at the Hpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b9578410b1f25c78b1a9dcd9107f51
https://pubmed.ncbi.nlm.nih.gov/18950699
https://pubmed.ncbi.nlm.nih.gov/18950699
Autor:
Elizabeth M. Simpson, Kevin A. Johnson, Connie L Mahaffey, Kathleen G. Banks, Charles P. Lerner, Roderick T. Bronson
Publikováno v:
Genomics. 82(3)
It is hypothesized that autosomal retroposons compensate for the loss of their inactivated essential X-chromosome progenitors during spermatogenesis. Here we test this Retroposon Compensatory Mechanism (RCM) hypothesis using the Zfy gene family. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f4ec9659c054fbcd47b2d1d6ba318c
https://pubmed.ncbi.nlm.nih.gov/12906850
https://pubmed.ncbi.nlm.nih.gov/12906850
Autor:
Dan Goldowitz, Elizabeth M. Simpson, Simone C McInerny, William W. Hauswirth, Robert A. Holt, Stéphanie Laprise, Michelle Zhou, Elodie Portales-Casamar, Shannon E. Boye, Cletus D'Souza, Kathleen G. Banks, Sanford L. Boye, Frank M. Dyka, Wyeth W. Wasserman, Charles N. de Leeuw, Steven J.M. Jones, Magdalena I. Swanson, Lisa J. Borretta, Alice Y Chou
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Critical for human gene therapy is the availability of small promoters tools to drive gene expression in a highly specific and reproducible manner. We tackled this challenge by developing human DNA MiniPromoters (MiniPs) using computational biology a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30997f1beb7eb5e96b226b34bf64a6f9
http://europepmc.org/articles/PMC3992516
http://europepmc.org/articles/PMC3992516