Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Kathleen F. Pirollo"'
Publikováno v:
Viruses, Vol 14, Iss 4, p 739 (2022)
SGT-53 is a novel investigational agent that comprises an immunoliposome carrying a plasmid vector driving expression of the human TP53 gene that encodes wild-type human p53. SGT-53 is currently in phase II human trials for advanced pancreatic cancer
Externí odkaz:
https://doaj.org/article/26b801d1165c4d7d9935b5d4b34184e7
Autor:
Carter Van Waes, Zhong Chen, Esther H. Chang, Kathleen F. Pirollo, Antonina Rait, Sang S. Kim, Andrew D. Cherniack, Steven J. M. Jones, A. Gordon Robertson, Richard V. Smith, Geoffrey J. Childs, Michael B. Prystowsky, Thomas M. Harris, Ludmila Danilova, Douglas Chepeha, Jamie Couper, Shaleeka Cornelius, Rita Das, Xinping Yang, Paul E. Clavijo, Sophie Carlson, Pinar Ormanoglu, Han Si, Scott E. Martin, Hui Cheng, Anthony D. Saleh
Supplementary Table S1, S3-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1463f964ae20d5f34b195246d4276602
https://doi.org/10.1158/1078-0432.22474164.v1
https://doi.org/10.1158/1078-0432.22474164.v1
Autor:
Carter Van Waes, Zhong Chen, Esther H. Chang, Kathleen F. Pirollo, Antonina Rait, Sang S. Kim, Andrew D. Cherniack, Steven J. M. Jones, A. Gordon Robertson, Richard V. Smith, Geoffrey J. Childs, Michael B. Prystowsky, Thomas M. Harris, Ludmila Danilova, Douglas Chepeha, Jamie Couper, Shaleeka Cornelius, Rita Das, Xinping Yang, Paul E. Clavijo, Sophie Carlson, Pinar Ormanoglu, Han Si, Scott E. Martin, Hui Cheng, Anthony D. Saleh
Purpose:To identify deregulated and inhibitory miRNAs and generate novel mimics for replacement nanomedicine for head and neck squamous cell carcinomas (HNSCC).Experimental Design:We integrated miRNA and mRNA expression, copy number variation, and DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c37363704fa2cc03491970fe6ae179
https://doi.org/10.1158/1078-0432.c.6528702.v1
https://doi.org/10.1158/1078-0432.c.6528702.v1
Autor:
Carter Van Waes, Zhong Chen, Esther H. Chang, Kathleen F. Pirollo, Antonina Rait, Sang S. Kim, Andrew D. Cherniack, Steven J. M. Jones, A. Gordon Robertson, Richard V. Smith, Geoffrey J. Childs, Michael B. Prystowsky, Thomas M. Harris, Ludmila Danilova, Douglas Chepeha, Jamie Couper, Shaleeka Cornelius, Rita Das, Xinping Yang, Paul E. Clavijo, Sophie Carlson, Pinar Ormanoglu, Han Si, Scott E. Martin, Hui Cheng, Anthony D. Saleh
Supplementary Methods, References, Figure legends, Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a7a3051d75b38d5dbd304d45ce18bc
https://doi.org/10.1158/1078-0432.22474158
https://doi.org/10.1158/1078-0432.22474158
Nanomedicine-Based Gene Delivery for a Truncated Tumor Suppressor RB94 Promotes Lung Cancer Immunity
Autor:
Sang-Soo Kim, Caroline Doherty, Manish Moghe, Antonina Rait, Kathleen F. Pirollo, Joe B. Harford, Esther H. Chang
Publikováno v:
Cancers; Volume 14; Issue 20; Pages: 5092
Because lung cancer remains the most common and lethal of cancers, novel therapeutic approaches are urgently needed. RB94 is a truncated form of retinoblastoma tumor suppressor protein with elevated anti-tumor efficacy. Our investigational nanomedici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1bbe8a6f8253d748af0e60bef34fbe
Autor:
Carter Van Waes, Scott E. Martin, Antonina Rait, Anthony Saleh, Geoffrey J. Childs, Thomas M. Harris, Pinar Ormanoglu, Rita Das, Andrew D. Cherniack, Jamie Couper, Michael B. Prystowsky, A. Gordon Robertson, Hui Cheng, Douglas B. Chepeha, Esther H. Chang, Shaleeka Cornelius, Zhong Chen, Sang S. Kim, Ludmila Danilova, Richard V. Smith, Han Si, Kathleen F. Pirollo, Sophie Carlson, Steven J.M. Jones, Paul E. Clavijo, Xinping Yang
Publikováno v:
Clin Cancer Res
Purpose: To identify deregulated and inhibitory miRNAs and generate novel mimics for replacement nanomedicine for head and neck squamous cell carcinomas (HNSCC). Experimental Design: We integrated miRNA and mRNA expression, copy number variation, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e81d24404425603c78337786cdbd77
https://doi.org/10.1158/1078-0432.ccr-18-0716
https://doi.org/10.1158/1078-0432.ccr-18-0716
Autor:
Gabriel Lopez-Berestein, Ke Liang, Farwah Rubab, Cristian Coarfa, Esther H. Chang, Anadulce Hernandez-Herrera, Preethi H. Gunaratne, Chunru Lin, Anil K. Sood, Amy C. Rowat, Avinashnarayan Venkatanarayan, Lingegowda S. Mangala, Elsa R. Flores, Ashley Benham, Kimal Rajapakshe, Abhi K. Rao, Sang-Soo Kim, Yinghong Pan, Antonina Rait, Kathleen F. Pirollo, Clara K. Chan
Publikováno v:
Cancer
Cancer, vol 125, iss 14
Cancer, vol 125, iss 14
Background Over 96% of high‐grade ovarian carcinomas and 50% of all cancers are characterized by alterations in the p53 gene. Therapeutic strategies to restore and/or reactivate the p53 pathway have been challenging. By contrast, p63, which shares
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac296d2df86a64109ebfc9f367f905b
http://europepmc.org/articles/PMC6617807
http://europepmc.org/articles/PMC6617807
Autor:
Kathleen F. Pirollo, John Dagata, Paul Wang, Matthew Freedman, Andras Vladar, Stanley Fricke, Lilia Ileva, Qi Zhou, Esther H. Chang
Publikováno v:
Molecular Imaging, Vol 5 (2006)
The development of improvements in magnetic resonance imaging (MRI) that would enhance sensitivity, leading to earlier detection of cancer and visualization of metastatic disease, is an area of intense exploration. We have devised a tumor-targeting,
Externí odkaz:
https://doaj.org/article/17c6bd6fd36d4e2aa45d06ff76655cb4
Autor:
Kathleen F. Pirollo, Joe B. Harford, Manish Moghe, Esther H. Chang, Antonina Rait, Sang-Soo Kim
Publikováno v:
Nucleic Acids Research
Intrinsic therapeutic resistance especially in cancer stem cells (CSCs) together with extensive tumor cell infiltration and restricted permeation of the blood-brain barrier (BBB) by drugs may all contribute to the treatment failure in patients with g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf801ca9d19344419ca86f7a01cadd2
http://europepmc.org/articles/PMC5815062
http://europepmc.org/articles/PMC5815062
Publikováno v:
Immune Aspects of Biopharmaceuticals and Nanomedicines ISBN: 9780203731536
Immune Aspects of Biopharmaceuticals and Nanomedicines
Immune Aspects of Biopharmaceuticals and Nanomedicines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8917f7b6d048f38e463f30f3a4eefa
https://doi.org/10.1201/b22372-30
https://doi.org/10.1201/b22372-30