Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kathleen E. Ertelt"'
Autor:
Anissa S H Chan, Adria Bykowski Jonas, Xiaohong Qiu, Nadine R Ottoson, Richard M Walsh, Keith B Gorden, Ben Harrison, Peter J Maimonis, Steven M Leonardo, Kathleen E Ertelt, Michael E Danielson, Kyle S Michel, Mariana Nelson, Jeremy R Graff, Myra L Patchen, Nandita Bose
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165909 (2016)
Imprime PGG (Imprime), an intravenously-administered, soluble β-glucan, has shown compelling efficacy in multiple phase 2 clinical trials with tumor targeting or anti-angiogenic antibodies. Mechanistically, Imprime acts as pathogen-associated molecu
Externí odkaz:
https://doaj.org/article/357100ff914f42d797e55b32fe9e7a5d
Autor:
Steven M. Leonardo, Ross B. Fulton, Kathryn A. Fraser, Mark T. Uhlik, Xiaohong Qiu, Jamie Lowe, Mark A. Matson, Keith B. Gorden, Lindsay R Jordan, Nadine R. Ottoson, Nandita Bose, Blaine Rathmann, Adria Jonas, Richard Walsh, Takashi O Kangas, Ben Harrison, Anissa S.H. Chan, Kathleen E. Ertelt, Jeremy R. Graff, Richard D. Huhn
Publikováno v:
The Journal of Immunology. 202:2945-2956
Imprime PGG (Imprime) is an i.v. administered, yeast β-1,3/1,6 glucan in clinical development with checkpoint inhibitors. Imprime-mediated innate immune activation requires immune complex formation with naturally occurring IgG anti-β glucan Abs (AB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3956a5f20a4932ae6bfbd8c850bad69e
https://doi.org/10.4049/jimmunol.1801533
https://doi.org/10.4049/jimmunol.1801533
Autor:
Ben J. Harrison, Nandita Bose, Xiaohong Qiu, Kyle S. Michel, Jeremy R. Graff, Richard Walsh, Mariana I. Nelson, Nadine R. Ottoson, Adria Jonas, Keith B. Gorden, Steven M. Leonardo, Michael E. Danielson, Kathleen E. Ertelt, Peter Maimonis, Anissa S.H. Chan, Myra L. Patchen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0165909 (2016)
PLoS ONE, Vol 11, Iss 11, p e0165909 (2016)
Imprime PGG (Imprime), an intravenously-administered, soluble β-glucan, has shown compelling efficacy in multiple phase 2 clinical trials with tumor targeting or anti-angiogenic antibodies. Mechanistically, Imprime acts as pathogen-associated molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58209753cfca1dd1d9d1f444649633e
http://europepmc.org/articles/PMC5094785
http://europepmc.org/articles/PMC5094785
Autor:
Ben J. Harrison, Keith B. Gorden, Jamie Lowe, Steven M. Leonardo, Richard Walsh, Mark Uhlik, Michael Chisamore, Kathleen E. Ertelt, Nandita Bose, Michele Gargano, Jeremy R. Graff, Bruno Osterwalder
Publikováno v:
Cancer Research. 78:LB-129
Imprime PGG is a novel, IV administered 1,3/1,6 β-glucan PAMP (pathogen-associated molecular pattern) that activates innate immune effector cells to enhance tumor killing, to repolarize the suppressive myeloid cells of the tumor microenvironment and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c06ba9f545602f2ddeae6033e994a69a
https://doi.org/10.1158/1538-7445.am2018-lb-129
https://doi.org/10.1158/1538-7445.am2018-lb-129
Autor:
Faimola Guerrero, Michael E. Danielson, Natalie Elmasry, Keith B. Gorden, John P. Vasilakos, Andrew S. Magee, Xiaohong Qiu, Anissa S.H. Chan, Myra L. Patchen, Carolyn M. Maristany, Richard Walsh, Kathleen E. Ertelt, Christine M. Dudney, Lindsay R. Wurst, Adria Jonas, Nandita Bose
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology
Frontiers in Immunology
The immunomodulatory properties of yeast β-1,3/1,6 glucans are mediated through their ability to be recognized by human innate immune cells. While several studies have investigated binding of opsonized and unopsonized particulate β-glucans to human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4feb377b175c4ace838233aecd7d2be1
http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00230/full
http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00230/full