Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kathleen E Huie"'
Autor:
Sirle Saul, Marwah Karim, Luca Ghita, Pei-Tzu Huang, Winston Chiu, Verónica Durán, Chieh-Wen Lo, Sathish Kumar, Nishank Bhalla, Pieter Leyssen, Farhang Alem, Niloufar A. Boghdeh, Do H.N. Tran, Courtney A. Cohen, Jacquelyn A. Brown, Kathleen E. Huie, Courtney Tindle, Mamdouh Sibai, Chengjin Ye, Ahmed Magdy Khalil, Kevin Chiem, Luis Martinez-Sobrido, John M. Dye, Benjamin A. Pinsky, Pradipta Ghosh, Soumita Das, David E. Solow-Cordero, Jing Jin, John P. Wikswo, Dirk Jochmans, Johan Neyts, Steven De Jonghe, Aarthi Narayanan, Shirit Einav
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Targeting host factors exploited by multiple viruses could offer broad-spectrum solutions for pandemic preparedness. Seventeen candidates targeting diverse functions emerged in a screen of 4,413 compounds for SARS-CoV-2 inhibitors. We demonstrated th
Externí odkaz:
https://doaj.org/article/9cc9d935abdc4025aa6c81ab75a6d932
Autor:
Kathryn Westendorf, Stefanie Žentelis, Lingshu Wang, Denisa Foster, Peter Vaillancourt, Matthew Wiggin, Erica Lovett, Robin van der Lee, Jörg Hendle, Anna Pustilnik, J. Michael Sauder, Lucas Kraft, Yuri Hwang, Robert W. Siegel, Jinbiao Chen, Beverly A. Heinz, Richard E. Higgs, Nicole L. Kallewaard, Kevin Jepson, Rodrigo Goya, Maia A. Smith, David W. Collins, Davide Pellacani, Ping Xiang, Valentine de Puyraimond, Marketa Ricicova, Lindsay Devorkin, Caitlin Pritchard, Aoise O’Neill, Kush Dalal, Pankaj Panwar, Harveer Dhupar, Fabian A. Garces, Courtney A. Cohen, John M. Dye, Kathleen E. Huie, Catherine V. Badger, Darwyn Kobasa, Jonathan Audet, Joshua J. Freitas, Saleema Hassanali, Ina Hughes, Luis Munoz, Holly C. Palma, Bharathi Ramamurthy, Robert W. Cross, Thomas W. Geisbert, Vineet Menachery, Kumari Lokugamage, Viktoriya Borisevich, Iliana Lanz, Lisa Anderson, Payal Sipahimalani, Kizzmekia S. Corbett, Eun Sung Yang, Yi Zhang, Wei Shi, Tongqing Zhou, Misook Choe, John Misasi, Peter D. Kwong, Nancy J. Sullivan, Barney S. Graham, Tara L. Fernandez, Carl L. Hansen, Ester Falconer, John R. Mascola, Bryan E. Jones, Bryan C. Barnhart
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110812- (2022)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 (COVID-19) when administered early. However, SARS-CoV-2 variants of c
Externí odkaz:
https://doaj.org/article/daeff3ff2f814504a3643f35bb419fcf
Autor:
Veronica M. Ringel-Scaia, Natalie Beitel-White, Melvin F. Lorenzo, Rebecca M. Brock, Kathleen E. Huie, Sheryl Coutermarsh-Ott, Kristin Eden, Dylan K. McDaniel, Scott S. Verbridge, John H. Rossmeisl, Jr, Kenneth J. Oestreich, Rafael V. Davalos, Irving C. Allen
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 112-125 (2019)
Background: Despite promising treatments for breast cancer, mortality rates remain high and treatments for metastatic disease are limited. High-frequency irreversible electroporation (H-FIRE) is a novel tumor ablation technique that utilizes high-fre
Externí odkaz:
https://doaj.org/article/8cdf471392134f86aabad70896d0c9d6
Autor:
Monica L Husby, Souad Amiar, Laura I Prugar, Emily A David, Caroline B Plescia, Kathleen E Huie, Jennifer M Brannan, John M Dye, Elsje Pienaar, Robert V Stahelin
Publikováno v:
EMBO reports. 23
Phosphatidylserine (PS) is a critical lipid factor in the assembly and spread of numerous lipid-enveloped viruses. Here, we describe the ability of the Ebola virus (EBOV) matrix protein eVP40 to induce clustering of PS and promote viral budding in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb529cf4843956aa9e693ee059c99dd
https://doi.org/10.15252/embr.202051709
https://doi.org/10.15252/embr.202051709
Autor:
Robert V. Stahelin, Monica L. Husby, Emily A. David, Plescia Cb, Laura I. Prugar, Souad Amiar, John M. Dye, Kathleen E. Huie, Elsje Pienaar, Jennifer M. Brannan
Phosphatidylserine (PS) has been shown to be a critical lipid factor in the assembly and spread of numerous lipid enveloped viruses. Here, we describe the ability of the Ebola virus (EBOV) matrix protein eVP40 to induce clustering of PS and promote v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e54f7ba2a36f7436775de2828fea477
https://doi.org/10.1101/2021.06.08.447555
https://doi.org/10.1101/2021.06.08.447555
Autor:
Sirle Saul, Marwah Karim, Luca Ghita, Pei-Tzu Huang, Winston Chiu, Verónica Durán, Chieh-Wen Lo, Sathish Kumar, Nishank Bhalla, Pieter Leyssen, Farhang Alem, Niloufar A. Boghdeh, Do HN Tran, Courtney A. Cohen, Jacquelyn A. Brown, Kathleen E. Huie, Courtney Tindle, Mamdouh Sibai, Chengjin Ye, Ahmed Magdy Khalil, Luis Martinez-Sobrido, John M. Dye, Benjamin A. Pinsky, Pradipta Ghosh, Soumita Das, David E. Solow-Cordero, Jing Jin, John P. Wikswo, Dirk Jochmans, Johan Neyts, Steven De Jonghe, Aarthi Narayanan, Shirit Einav
Targeting host factors exploited by multiple viruses could offer broad-spectrum solutions for pandemic preparedness. Seventeen candidates targeting diverse functions emerged in a screen of 4,413 compounds for SARS-CoV-2 inhibitors. We demonstrated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcd80e2a2ac97bdced0f99fed6e8c8f8
https://doi.org/10.1101/2021.05.15.444128
https://doi.org/10.1101/2021.05.15.444128
Autor:
Kathryn Westendorf, Stefanie Žentelis, Lingshu Wang, Denisa Foster, Peter Vaillancourt, Matthew Wiggin, Erica Lovett, Robin van der Lee, Jörg Hendle, Anna Pustilnik, J. Michael Sauder, Lucas Kraft, Yuri Hwang, Robert W. Siegel, Jinbiao Chen, Beverly A. Heinz, Richard E. Higgs, Nicole L. Kallewaard, Kevin Jepson, Rodrigo Goya, Maia A. Smith, David W. Collins, Davide Pellacani, Ping Xiang, Valentine de Puyraimond, Marketa Ricicova, Lindsay Devorkin, Caitlin Pritchard, Aoise O’Neill, Kush Dalal, Pankaj Panwar, Harveer Dhupar, Fabian A. Garces, Courtney A. Cohen, John M. Dye, Kathleen E. Huie, Catherine V. Badger, Darwyn Kobasa, Jonathan Audet, Joshua J. Freitas, Saleema Hassanali, Ina Hughes, Luis Munoz, Holly C. Palma, Bharathi Ramamurthy, Robert W. Cross, Thomas W. Geisbert, Vineet Menacherry, Kumari Lokugamage, Viktoriya Borisevich, Iliana Lanz, Lisa Anderson, Payal Sipahimalani, Kizzmekia S. Corbett, Eun Sung Yang, Yi Zhang, Wei Shi, Tongqing Zhou, Misook Choe, John Misasi, Peter D. Kwong, Nancy J. Sullivan, Barney S. Graham, Tara L. Fernandez, Carl L. Hansen, Ester Falconer, John R. Mascola, Bryan E. Jones, Bryan C. Barnhart
Publikováno v:
bioRxiv
SARS-CoV-2 neutralizing monoclonal antibodies (mAbs) can reduce the risk of hospitalization when administered early during COVID-19 disease. However, the emergence of variants of concern has negatively impacted the therapeutic use of some authorized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb8cf2c168e04af64aeb77ae8c382f6
https://europepmc.org/articles/PMC8109210/
https://europepmc.org/articles/PMC8109210/
Autor:
Jimmy Gollihar, David Bernard, Vivek Kapur, Abhinay Gontu, Gregory C. Ippolito, Sreenidhi Srinivasan, Randall M. Rossi, Indira Poojary, Laura I. Prugar, Randall J. Olsen, Eric Salazar, Peter J. Hudson, Jose A. Cardona, James M. Musser, Ian M. Bird, Zhicheng Jin, Nicole M. Josleyn, Todd N. Eagar, Denver Greenawalt, Picheng Zhao, Kathleen E. Huie, John M. Dye, Dalton M Towers, Suresh V. Kuchipudi, Jian Chen, Andrew S. Herbert, Christopher Leveque, Xin Yi, Isabella M. Cattadori, Ruth H. Nissly, Brian Castillo, Jason J. Lavinder, S. Wesley Long, Paul A. Christensen
Publikováno v:
J Clin Invest
bioRxiv
article-version (status) pre
article-version (number) 1
bioRxiv
article-version (status) pre
article-version (number) 1
Newly emerged pathogens such as SARS-CoV-2 highlight the urgent need for assays that detect levels of neutralizing antibodies that may be protective. We studied the relationship between anti-spike ectodomain (ECD) and anti-receptor binding domain (RB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22021f76c75c2351c162e981d74ff6a8
https://europepmc.org/articles/PMC7685744/
https://europepmc.org/articles/PMC7685744/
Autor:
Ruth H. Nissly, Laura I. Prugar, Peter J. Hudson, Eric Salazar, Nicole Joselyn, S. Wesley Long, Abinhay Gontu, Picheng Zhao, José Rubén Parra Cardona, Vivek Kapur, Suresh V. Kuchipudi, Zhicheng Jin, Denver Greenawalt, Sreenidhi Srinivasan, David W. Bernard, Randall M. Rossi, Randall J. Olsen, Jason J. Lavinder, Indira Poojary, Ian M. Bird, Andrew S. Herbert, Xin Yi, Isabella M. Cattadori, Gregory C. Ippolito, John M. Dye, Dalton M Towers, Brian Castillo, James M. Musser, Jian Chen, Paul A. Christensen, Jimmy Gollihar, Kathleen E. Huie, Todd N. Eagar, Christopher Leveque
Newly emerged pathogens such as SARS-CoV-2 highlight the urgent need for assays that detect levels of neutralizing antibodies that may be protective. We studied the relationship between anti-spike ectodomain (ECD) and anti-receptor binding domain (RB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aa5962ab22ea3bd35b642d894fb2cca
https://doi.org/10.1101/2020.06.08.138990
https://doi.org/10.1101/2020.06.08.138990
Autor:
Kristin Eden, Rebecca M. Brock, John H. Rossmeisl, Natalie Beitel-White, Sheryl Coutermarsh-Ott, Veronica M. Ringel-Scaia, Rafael V. Davalos, Scott S. Verbridge, Kenneth J. Oestreich, Melvin F. Lorenzo, Kathleen E. Huie, Irving C. Allen, Dylan K. McDaniel
Background: Despite promising treatments for breast cancer, mortality rates remain high and treatments for metastatic disease are limited. High-frequency irreversible electroporation (H-FIRE) is a novel tumor ablation technique that utilizes high-fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d9702c2e9585d79033b9076aa7cee8
https://europepmc.org/articles/PMC6606957/
https://europepmc.org/articles/PMC6606957/