Zobrazeno 1 - 10 of 61 pro vyhledávání: '"Kathleen E, Wiley"'
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Data from A Novel Prostate Cancer Susceptibility Locus at 19q13
Autor: S. Lilly Zheng, Jianfeng Xu, Henrik Grönberg, William B. Isaacs, John D. Carpten, David Duggan, Patrick C. Walsh, Bao-Li Chang, Wennuan Liu, Zheng Zhang, Seong-Tae Kim, Yi Zhu, Pär Stattin, Zhengrong Gao, Lina D. Purcell, Kathleen E. Wiley, Sarah D. Isaacs, Fredrik Wiklund, Jielin Sun, Fang-Chi Hsu
A two-stage genome-wide association study (GWAS) of the Cancer Genetic Markers of Susceptibility (CGEMS) initiative identified single nucleotide polymorphisms (SNP) in 150 regions across the genome that may be associated with prostate cancer (PCa) ri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d302afdc5ff7ecb36f67427330a5339
https://doi.org/10.1158/0008-5472.c.6499595.v1
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8
Validation of a prostate cancer polygenic risk score
Autor: Shuwei Li, Robert Hoiness, Siqun Lilly Zheng, Brian T. Helfand, Mary Helen Black, Jun Wei, Jefferey Chen, Jianfeng Xu, Kathleen E. Wiley, Stephanie Gutierrez, Brigette Tippin-Davis, Min-Tzu Lo, Hsiao Mei Lu, William B. Isaacs, Holly LaDuca, Zhuqing Shi, Marta Gielzak
Publikováno v: The Prostate
Background Genome‐wide association studies have identified over 100 single‐nucleotide polymorphisms (SNPs) associated with prostate cancer (PrCa), and polygenic risk scores (PRS) based on their combined genotypes have been developed for risk stra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeae415641ec22d8b744367012fae5dd
https://doi.org/10.1002/pros.24058
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10
Germline mutations in PPFIBP2 are associated with lethal prostate cancer
Autor: Yishuo Wu, Siqun Lilly Zheng, William B. Isaacs, Julie L. Boyle, Charles M. Ewing, Bing Jian Feng, Ashley L. Kapron, Zhuqing Shi, H.B. Carter, Hongjie Yu, Rong Na, Sameep Shah, Jianfeng Xu, Patrick C. Walsh, Kathleen E. Wiley, Jun Luo, Brian T. Helfand, Kathleen A. Cooney
Publikováno v: The Prostate. 78:1222-1228
BACKGROUND Few genes have germline mutations which predispose men to more aggressive prostate cancer (PCa). This study evaluated the contribution of germline loss of function (LOF) variants in PPFIBP2 to risk of lethal PCa. METHODS A case-case study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6a1709fe5e9d009f4149e5ad211f35
https://doi.org/10.1002/pros.23697
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