Malaria-specific Type 1 regulatory T cells are more abundant in first pregnancies and associated with placental malariaResearch in context

Autor: Adam S. Kirosingh, Alea Delmastro, Abel Kakuru, Kattria van der Ploeg, Sanchita Bhattacharya, Kathleen D. Press, Maureen Ty, Lauren de la Parte, Jimmy Kizza, Mary Muhindo, Sebastien Devachanne, Benoit Gamain, Felistas Nankya, Kenneth Musinguzi, Philip J. Rosenthal, Margaret E. Feeney, Moses Kamya, Grant Dorsey, Prasanna Jagannathan

Publikováno v: EBioMedicine, Vol 95, Iss , Pp 104772- (2023)

Summary: Background: Malaria in pregnancy (MIP) causes higher morbidity in primigravid compared to multigravid women; however, the correlates and mechanisms underlying this gravidity-dependent protection remain incompletely understood. We aimed to co

Externí odkaz: https://doaj.org/article/9f6a49994d584a3ebeb8ae5049f6348a

Disease Tolerance of Malaria Involves Epigenetic Reprogramming of Innate Immune Cells

Autor: Jason Nideffer, Maureen Caracena Ty, Michele Donato, Rek John, Richard Kajubi, Xuhuai Ji, Felistas Nankya, Kenneth Musinguzi, Kathleen D. Press, Bryan Greenhouse, Moses Kamya, Margo Feeney, Grant Dorsey, PJ Utz, Bali Pulendran, Purvesh Khatri, Prasanna Jagannathan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee83cde083f3f9f71091be2ac378963e
https://doi.org/10.2139/ssrn.4436849

TNF-α

Autor: Kattria, van der Ploeg, Adam S, Kirosingh, Diego A M, Mori, Saborni, Chakraborty, Zicheng, Hu, Benjamin L, Sievers, Karen B, Jacobson, Hector, Bonilla, Julie, Parsonnet, Jason R, Andrews, Kathleen D, Press, Maureen C, Ty, Daniel R, Ruiz-Betancourt, Lauren, de la Parte, Gene S, Tan, Catherine A, Blish, Saki, Takahashi, Isabel, Rodriguez-Barraquer, Bryan, Greenhouse, Upinder, Singh, Taia T, Wang, Prasanna, Jagannathan

Publikováno v: Cell reports. Medicine. 3(6)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific CD4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b0db420c914bb6190998cbade5bc81cf
https://pubmed.ncbi.nlm.nih.gov/35588734

TNFα-Producing CD4 + T Cells Dominate the SARS-CoV-2-Specific T Cell Response in COVID-19 Outpatients and Are Associated with Durable Antibodies

Autor: Kattria van der Ploeg, Adam Setori Kirosingh, Diego Alonzo Martinez Mori, Saborni Chakraborty, Zicheng Hu, Benjamin L. Seivers, Karen B. Jacobson, Hector Bonilla, Julie Parsonnet, Jason Andrews, Kathleen D. Press, Maureen Caracena Ty, Daniel R. Ruiz-Betancourt, Lauren de la Parte, Gene S. Tan, Catherine Blish, Saki Takahashi, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Upinder Singh, Taia Wang, Prasanna Jagannathan

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a428c2297403ccfcdfb6640099c92544
https://doi.org/10.2139/ssrn.4019718

Natural killer cell antibody‐dependent cellular cytotoxicity to Plasmodium falciparum is impacted by cellular phenotypes, erythrocyte polymorphisms, parasite diversity and intensity of transmission.

Autor: Tukwasibwe, Stephen^1,2 (AUTHOR), Lewis, Savannah Nicole³ (AUTHOR), Taremwa, Yoweri¹ (AUTHOR), van der Ploeg, Kattria³ (AUTHOR), Press, Kathleen D³ (AUTHOR), Ty, Maureen³ (AUTHOR), Namirimu Nankya, Felistas¹ (AUTHOR), Musinguzi, Kenneth¹ (AUTHOR), Nansubuga, Evelyn¹ (AUTHOR), Bach, Florian³ (AUTHOR), Chamai, Martin¹ (AUTHOR), Okitwi, Martin¹ (AUTHOR), Tumusiime, Gerald² (AUTHOR), Nakimuli, Annettee⁴ (AUTHOR), Colucci, Francesco⁵ (AUTHOR), Kamya, Moses R^1,4 (AUTHOR), Nankabirwa, Joaniter I^1,4 (AUTHOR), Arinaitwe, Emmanuel¹ (AUTHOR), Greenhouse, Bryan⁶ (AUTHOR), Dorsey, Grant⁶ (AUTHOR)

Publikováno v: Clinical & Translational Immunology. 2024, Vol. 13 Issue 11, p1-16. 16p.