Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kathleen C. Lehmann"'
Autor:
Dmitry V. Samborskiy, Eric J. Snijder, Mark Ruben, Peter A. van Veelen, George M.C. Janssen, Anastasia A. Gulyaeva, Igor A. Sidorov, Alexander E. Gorbalenya, Hermen S. Overkleeft, Kathleen C. Lehmann, Andrey M. Leontovich, Alexander A. Kravchenko, Jessika C. Zevenhoven-Dobbe, Clara C. Posthuma
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 43(17), 8416-8434
Nucleic Acids Research, 43(17), 8416-8434
RNA viruses encode an RNA-dependent RNA polymerase (RdRp) that catalyzes the synthesis of their RNA(s). In the case of positive-stranded RNA viruses belonging to the order Nidovirales, the RdRp resides in a replicase subunit that is unusually large.
Publikováno v:
Virology
Virology, 487, 68-74
Virology, 487, 68-74
All RNA viruses encode an RNA-dependent RNA polymerase (RdRp), which in arteriviruses is expressed as the C-terminal domain of nonstructural protein 9 (nsp9). Previously, potent primer-dependent RdRp activity has been demonstrated for the homologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bf9e95511fda01497c1e78f67659ed
https://hdl.handle.net/1887/102078
https://hdl.handle.net/1887/102078
Autor:
Lisa Hooghiemstra, Jessika C. Zevenhoven-Dobbe, Clara C. Posthuma, Kathleen C. Lehmann, Anastasia A. Gulyaeva, Eric J. Snijder, Alexander E. Gorbalenya, Dmitry V. Samborskiy
Publikováno v:
Journal of General Virology, 96, 2643-2655
The 3′-terminal domain of the most conserved ORF1b in three of the four families of the order Nidovirales (except for the family Arteriviridae) encodes a (putative) 2′-O-methyltransferase (2′-O-MTase), known as non structural protein (nsp) 16 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be497189268f8cdfc2a7bd24977d540f
http://hdl.handle.net/1887/105180
http://hdl.handle.net/1887/105180
Autor:
Xiaoxuan Qi, Wen-hai Feng, Wei Wu, C.C. (Clara) Posthuma, Xiaorong Li, Ye Tao, Lin Yu, Alexander E. Gorbalenya, Xingliang Zhang, Chong Feng, Zengqin Deng, Kathleen C. Lehmann, Eric J. Snijder, Guoqiang Wang, Peng Gong, Zhongzhou Chen, Qi Zhang
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 42(5), 3464-3477
Nucleic Acids Research, 42(5), 3464-3477
All positive-stranded RNA viruses with genomes >∼7 kb encode helicases, which generally are poorly characterized. The core of the nidovirus superfamily 1 helicase (HEL1) is associated with a unique N-terminal zinc-binding domain (ZBD) that was prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13dc8ec23a42d4d3c2744d9b24c671dc
https://hdl.handle.net/1887/105193
https://hdl.handle.net/1887/105193