Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kathleen Bengali"'
Autor:
Daniel V T Catenacci, Wei-Li Liao, Sheeno Thyparambil, Les Henderson, Peng Xu, Lei Zhao, Brittany Rambo, John Hart, Shu-Yuan Xiao, Kathleen Bengali, Jamar Uzzell, Marlene Darfler, David B Krizman, Fabiola Cecchi, Donald P Bottaro, Theodore Karrison, Timothy D Veenstra, Todd Hembrough, Jon Burrows
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100586 (2014)
Overexpression of Met tyrosine kinase receptor is associated with poor prognosis. Overexpression, and particularly MET amplification, are predictive of response to Met-specific therapy in preclinical models. Immunohistochemistry (IHC) of formalin-fix
Externí odkaz:
https://doaj.org/article/63bb698729444933a2050156f8451ab8
Autor:
Daniel V.T. Catenacci, Les Henderson, David Krisman, Shu-Yuan Xiao, Todd Hembrough, Lei Zhao, Sheeno Thyparambil, Wei-Li Liao, Kathleen Bengali, Emma Whitcomb, Jamar Uzzell, Emily O'Day, Peng Xu, Adele Blackler, John Hart, Sang Mee Lee, Yung-Jue Bang, Marlene Darfler, Jon Burrows, Fabiola Cecchi
Publikováno v:
Gastric Cancer. 19:1066-1079
Trastuzumab has shown a survival benefit in cases of Her2-positive gastroesophageal cancer (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for trastuzumab-based therapy. However, these l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbd172279a97844ddf028dc22990161
https://doi.org/10.1007/s10120-015-0566-0
https://doi.org/10.1007/s10120-015-0566-0
Autor:
Peng Xu, Yung-Jue Bang, Adele Blackler, Emma Whitcomb, Shu-Yuan Xiao, Jamar Uzzell, John Hart, Kathleen Bengali, Fabiola Cecchi, Wei-Li Liao, Emily O'Day, Daniel V.T. Catenacci, Sheeno Thyparambil, David Krisman, Marlene Darfler, Todd Hembrough, Lei Zhao, Jon Burrows, Les Henderson, Sang Mee Lee
Background: Trastuzumab showed survival benefit for Her2-positive gastroesophageal cancers (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for trastuzumab-based therapy. However, both as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad9f3afd0ac82c630a28a0c8c252584
Autor:
Shu-Yuan Xiao, Brittany Rambo, Fabiola Cecchi, Jon Burrows, Daniel V.T. Catenacci, Wei-Li Liao, Lei Zhao, David B. Krizman, Kathleen Bengali, Peng Xu, Theodore Karrison, Jamar Uzzell, Marlene Darfler, Les Henderson, Todd Hembrough, Sheeno Thyparambil, John Hart, Donald P. Bottaro, Timothy D. Veenstra
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100586 (2014)
PLoS ONE
PLoS ONE
Background Overexpression of Met tyrosine kinase receptor is associated with poor prognosis. Overexpression, and particularly MET amplification, are predictive of response to Met-specific therapy in preclinical models. Immunohistochemistry (IHC) of f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d71786fbe08a62b2dee0a68f0cdd40
http://europepmc.org/articles/PMC4077664?pdf=render
http://europepmc.org/articles/PMC4077664?pdf=render
Autor:
Jon Burrows, Stephen M. Hewitt, Marlene Darfler, Todd Hembrough, Richard A. Bender, Wei-Li Liao, David B. Krizman, Joseph Abdo, Kathleen Bengali, Sheeno Thyparambil
Publikováno v:
The Journal of molecular diagnostics : JMD. 15(4)
One of the critical gaps in the clinical diagnostic space is the lack of quantitative proteomic methods for use on formalin-fixed, paraffin-embedded (FFPE) tissue. Herein, we describe the development of a quantitative, multiplexed, mass spectrometry-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472c90c757115f72520677b7e9e04f5a
https://pubmed.ncbi.nlm.nih.gov/23672976
https://pubmed.ncbi.nlm.nih.gov/23672976
Autor:
Kathleen Bengali, Adele Blackler, Wei-Li Liao, Jamar Uzzell, Jon Burrows, Eunkyung An, Sheeno Thyparambil, Todd Hembrough, Marlene Darfler
Publikováno v:
Cancer Research. 74:918-918
Background: Current cancer treatment regimens rely on the use of chemotherapy agents that inhibit DNA replication and repair machinery. Several proteins are involved in this mechanism, such as TOPO1, TOPO2A, RRM1, FR-alpha and hENT1. The expression l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301e0100904688b8a0bbcca0e10fa6ea
https://doi.org/10.1158/1538-7445.am2014-918
https://doi.org/10.1158/1538-7445.am2014-918
Publikováno v:
Cytokine. 9(1)
Two receptors for interleukin 8 (IL-8), IL-8rA and IL-8rB, have been cloned. Previous studies of neutrophils indicated that the two C-X-C chemokines, IL-8 and NAP-2, bind to IL-8rB with high affinity but that only IL-8 binds to IL-8rA with high affin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844f4e71838c8d63ed1dcff98d02b65b
https://pubmed.ncbi.nlm.nih.gov/9067094
https://pubmed.ncbi.nlm.nih.gov/9067094
Autor:
Kathleen Bengali, Jon Burrows, Sheeno Thyparambil, Wei-Li Liao, David B. Krizman, Marlene Darfler, Joe Abdo, Todd Hembrough
Publikováno v:
Cancer Research. 72:4567-4567
The human EGF receptor family (HER's) consists of two clinically validated drug targets (EGFR (HER1) and HER2), and two receptors (HER3 and HER4) which are the subject of intensive preclinical and early clinical investigation. Although drugs inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b0376f0d4235e84059527bc63b35f3
https://doi.org/10.1158/1538-7445.am2012-4567
https://doi.org/10.1158/1538-7445.am2012-4567
Autor:
Sheeno Thyparambil, Joe Abdo, Kathleen Bengali, Wei-Li Liao, David B. Krizman, Marlene Darfler, Jon Burrows, Todd Hembrough
Publikováno v:
Molecular Cancer Therapeutics. 10:A152-A152
The human EGF receptor family (HER's) consists of two clinically validated drug targets (EGFR and Her2), and two receptors (Her3 and Her4) which are the subject of intensive preclinical and early clinical investigation. Although drugs inhibiting both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b9d3844129e24eb697d533ff05c29eb
https://doi.org/10.1158/1535-7163.targ-11-a152
https://doi.org/10.1158/1535-7163.targ-11-a152
Autor:
David B. Krizman, Joe Abdo, Todd Hembrough, Jon Burrows, Marlene Darfler, Sheeno Thyparambil, Kathleen Bengali
Publikováno v:
Cancer Research. 71:1514-1514
The observation that cancer cells can undergo aerobic glycolosis (the Warburg Effect) has been the target of a great deal of research in recent years, specifically directed to development of novel agents which can disrupt this pathway and potentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8adc7cb395ed3159283a01ae779fcce1
https://doi.org/10.1158/1538-7445.am2011-1514
https://doi.org/10.1158/1538-7445.am2011-1514