Zobrazeno 1 - 10
of 724
pro vyhledávání: '"Kathleen A. Sullivan"'
Autor:
Gonench Kilich, Kelly Hassey, Edward M. Behrens, Marni Falk, Adeline Vanderver, Daniel J. Rader, Patrick J. Cahill, Anna Raper, Zhe Zhang, Dawn Westerfer, Tanaya Jadhav, Laura Conlin, Kosuke Izumi, Ramakrishnan Rajagopalan, Kathleen E. Sullivan, UDN Consortium
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-6 (2024)
Abstract Kagami–Ogata syndrome is a rare imprinting disorder and its phenotypic overlap with multiple different etiologies hampers diagnosis. Genetic etiologies include paternal uniparental isodisomy (upd(14)pat), maternal allele deletions of diffe
Externí odkaz:
https://doaj.org/article/18c87511f1c04d91a6e404df341c6e2e
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background Fibroblast-like synoviocytes (FLS) play a crucial role in JIA pathogenesis; however, the mechanisms by which they contribute to disease progression are not well described. Previous studies demonstrated that rheumatoid arthritis FL
Externí odkaz:
https://doaj.org/article/7b79c4f9ea3f4237b84ce004cb01f5df
Autor:
Matthew C. Pahl, Carole Le Coz, Chun Su, Prabhat Sharma, Rajan M. Thomas, James A. Pippin, Emylette Cruz Cabrera, Matthew E. Johnson, Michelle E. Leonard, Sumei Lu, Alessandra Chesi, Kathleen E. Sullivan, Neil Romberg, Struan F. A. Grant, Andrew D. Wells
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background SARS-CoV-2 infection results in a broad spectrum of COVID-19 disease, from mild or no symptoms to hospitalization and death. COVID-19 disease severity has been associated with some pre-existing conditions and the magnitude of the
Externí odkaz:
https://doaj.org/article/8df9b6167b7e4c4c861156596c1735c6
Autor:
Caroline Diorio, Rawan Shraim, Laura A. Vella, Josephine R. Giles, Amy E. Baxter, Derek A. Oldridge, Scott W. Canna, Sarah E. Henrickson, Kevin O. McNerney, Frances Balamuth, Chakkapong Burudpakdee, Jessica Lee, Tomas Leng, Alvin Farrel, Michele P. Lambert, Kathleen E. Sullivan, E. John Wherry, David T. Teachey, Hamid Bassiri, Edward M. Behrens
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Multi-inflammatory syndrome in children (MIS-C) can be associated with SARS-CoV-2 infection but can also be similar to other inflammatory syndromes. Here the authors characterise the plasma proteome phenotype in MIS-C and compare to other SARS-CoV-2
Externí odkaz:
https://doaj.org/article/a888480056e0487995e0516acf1b06ce
Autor:
Eliana Shaul, Máire A. Conrad, Noor Dawany, Trusha Patel, Megan C. Canavan, Alyssa Baccarella, Sarah Weinbrom, Daniel Aleynick, Kathleen E. Sullivan, Judith R. Kelsen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionTherapeutic options are critically needed for children with refractory very early onset inflammatory bowel disease (VEO-IBD). Our aim was to evaluate clinical response to canakinumab, an anti-IL-1β monoclonal antibody, in patients with V
Externí odkaz:
https://doaj.org/article/b6ac90a53ff746f68ce9c1bd64b099f7
Autor:
Paulina Tran, Laura Gober, Elizabeth K. Garabedian, Ramsay L. Fuleihan, Jennifer M. Puck, Kathleen E. Sullivan, Jonathan M. Spergel, Melanie A. Ruffner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
RationaleEosinophilic gastrointestinal disorders (EGID), including eosinophilic esophagitis (EoE), are inflammatory disorders of the gastrointestinal mucosa mediated by complex immune mechanisms. Although there have been initial reports of EGID in pa
Externí odkaz:
https://doaj.org/article/8d040440ecdd488682ba0dce651efc75
Autor:
Megan M. Simonds, Amanda R. Schlefman, Suzanne M. McCahan, Kathleen E. Sullivan, Carlos D. Rose, Anne Marie C. Brescia
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background We examined influences of conditioned media from chondrocytes (Ch) on juvenile idiopathic arthritis synovial fibroblasts (JFLS) and potential for JFLS to undergo endochondral bone formation (EBF). Methods Primary cells from three
Externí odkaz:
https://doaj.org/article/13705dac5fd5449c9a624955eef8b137
Autor:
Michelle A Petri, Emily von Scheven, Marisa S Klein-Gitelman, Patricia Costa-Reis, Kelly Maurer, Kathleen E Sullivan, Daniella Levy Erez, Xue Zhao, Walter Faig, Jon Burnham, Kathleen O'Neil
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Objective Lupus nephritis is a key driver of morbidity and mortality in SLE. Detecting active nephritis on a background of pre-existing renal damage is difficult, leading to potential undertreatment and accumulating injury. An unmet need is a biomark
Externí odkaz:
https://doaj.org/article/65699cef0c59422a86921fb9a6855bc0
Autor:
Megan M. Simonds, Amanda R. Schlefman, Suzanne M. McCahan, Kathleen E. Sullivan, Carlos D. Rose, AnneMarie C. Brescia
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background To examine critical interactions between juvenile idiopathic arthritis synovial fibroblasts (JFLS) and chondrocytes (Ch), and their role in bony overgrowth seen in patients with juvenile idiopathic arthritis (JIA). Methods Control
Externí odkaz:
https://doaj.org/article/30a8bb8bee884e04ad7d159f043c8a31
Autor:
Kelsey L. Smith, Darlene Dai, Bhavi P. Modi, Rahnuma Sara, Elizabeth Garabedian, Rebecca A. Marsh, Jennifer Puck, Elizabeth Secord, Kathleen E. Sullivan, Stuart E. Turvey, Catherine M. Biggs, the USIDNET Consortium
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundMonogenic conditions that disrupt proper development and/or function of the immune system are termed inborn errors of immunity (IEIs), also known as primary immunodeficiencies. Patients with IEIs often suffer from other manifestations in ad
Externí odkaz:
https://doaj.org/article/53014f5c22f549b8a7f3940cf042569c