Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kathleen A. Ottina"'
Autor:
Zachary A. Cooper, Kris C. Wood, Ashley Peraza-Penton, Jennifer A. Wargo, J. Jasper, Keith T. Flaherty, Holly M. Alley, Katherine R. Singleton, Colin A. Martz, Suzanne E. Wardell, Michael T. Tetzlaff, Kathleen A. Ottina, Timothy C. Wang, Peter S. Winter, Pei Ling Chen, Jeffrey C. Rathmell, Grace R. Anderson, David M. Sabatini, Donald P. McDonnell, Lawrence N. Kwong
Publikováno v:
Science signaling. 7(357)
Cancer cells can activate diverse signaling pathways to evade the cytotoxic action of drugs. We created and screened a library of barcoded pathway-activating mutant complementary DNAs to identify those that enhanced the survival of cancer cells in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1ef53840517193c84123b9e948db49
https://pubmed.ncbi.nlm.nih.gov/25538079
https://pubmed.ncbi.nlm.nih.gov/25538079
Autor:
David M. Sabatini, Anne E. Carpenter, Carson C. Thoreen, David A. Guertin, Siraj M. Ali, Katherine L. Madden, Robert A. Lindquist, Michael R. Lamprecht, Adam Papallo, Peggy P. Hsu, Kathleen A. Ottina, Shomit Sengupta, Thouis R. Jones, Yoav D. Shaul, Douglas B. Wheeler
Publikováno v:
Cold Spring Harbor Laboratory Press
The evolutionarily conserved target of rapamycin complex 1 (TORC1) controls cell growth in response to nutrient availability and growth factors. TORC1 signaling is hyperactive in cancer, and regulators of TORC1 signaling may represent therapeutic tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8a4cf4de0eb3a16d0146240f06adb3
http://hdl.handle.net/1721.1/74542
http://hdl.handle.net/1721.1/74542
