Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Kathleen A. Farley"'
Autor:
David Jonathan Wasilko, Brian S. Gerstenberger, Kathleen A. Farley, Wei Li, Jennifer Alley, Mark E. Schnute, Ray J. Unwalla, Jorge Victorino, Kimberly K. Crouse, Ru Ding, Parag V. Sahasrabudhe, Fabien Vincent, Richard K. Frisbie, Alpay Dermenci, Andrew Flick, Chulho Choi, Gary Chinigo, James J. Mousseau, John I. Trujillo, Philippe Nuhant, Prolay Mondal, Vincent Lombardo, Daniel Lamb, Barbara J. Hogan, Gurdeep Singh Minhas, Elena Segala, Christine Oswald, Ian W. Windsor, Seungil Han, Mathieu Rappas, Robert M. Cooke, Matthew F. Calabrese, Gabriel Berstein, Atli Thorarensen, Huixian Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The CC chemokine receptor 6 (CCR6) is a potential target for chronic inflammatory diseases. Previously, we reported an active CCR6 structure in complex with its cognate chemokine CCL20, revealing the molecular basis of CCR6 activation. Here,
Externí odkaz:
https://doaj.org/article/91af6bd491994266b492f68b0994ea6e
Publikováno v:
Ecology and Society, Vol 22, Iss 1, p 38 (2017)
Working landscapes such as rangelands are increasingly recognized as having high conservation value, providing a variety of ecosystem services, including food, fiber, habitat, recreation, open space, carbon storage, and water, in addition to a broad
Externí odkaz:
https://doaj.org/article/fcbeec3555a74cf1b10021e2a177ce6d
Autor:
Michelle R. Garnsey, Aaron C. Smith, Jana Polivkova, Autumn L. Arons, Guoyun Bai, Caroline Blakemore, Markus Boehm, Leanne M. Buzon, Sarah N. Campion, Matthew Cerny, Shiao-Chi Chang, Karen Coffman, Kathleen A. Farley, Kari R. Fonseca, Kristen K. Ford, Jeonifer Garren, Jimmy X. Kong, Martin R. M. Koos, Daniel W. Kung, Yajing Lian, Monica M. Li, Qifang Li, Luis A. Martinez-Alsina, Rebecca O’Connor, Kevin Ogilvie, Kiyoyuki Omoto, Brian Raymer, Matthew R. Reese, Tim Ryder, Lacey Samp, Kimberly A. Stevens, Daniel W. Widlicka, Qingyi Yang, Kaicheng Zhu, Jean-Philippe Fortin, Matthew F. Sammons
Publikováno v:
Journal of Medicinal Chemistry. 66:3195-3211
Autor:
Zachary Lee Johnson, Mark Ammirati, David Jonathan Wasilko, Jeanne S. Chang, Stephen Noell, Timothy L. Foley, Hyejin Yoon, Kathleen Smith, Shoh Asano, Katherine Hales, Min Wan, Qingyi Yang, Mary A. Piotrowski, Kathleen A. Farley, Tamara Gilbert, Lisa M. Aschenbrenner, Kimberly F. Fennell, Jason K. Dutra, Mary Xu, Chunyang Guo, Alison E. Varghese, Justin Bellenger, Alandra Quinn, Christopher W. am Ende, Graham M. West, Matthew C. Griffor, Donald Bennett, Matthew Calabrese, Claire M. Steppan, Seungil Han, Huixian Wu
Publikováno v:
Nature Structural & Molecular Biology. 30:22-30
Glycerol-3-phosphate acyltransferase (GPAT)1 is a mitochondrial outer membrane protein that catalyzes the first step of de novo glycerolipid biosynthesis. Hepatic expression of GPAT1 is linked to liver fat accumulation and the severity of nonalcoholi
Autor:
Roberto R. Gil, Chris Limberakis, Kathleen A. Farley, Ricardo Lira, Justin Bellenger, Ye Che, Martin R. M. Koos, Leandro F. Gil‐Silva, Reto Horst
Publikováno v:
Angewandte Chemie International Edition. 60:26314-26319
Determination of the solution conformation of both small organic molecules and peptides in water remains a substantial hurdle in using NMR solution conformations to guide drug design due to the lack of easy to use alignment media. Herein we report th
Publikováno v:
Energies, Vol 8, Iss 8, Pp 8355-8370 (2015)
The efficiency of wireless power transfer is sensitive to the horizontal and vertical distances between the transmitter and receiver coils due to the magnetic coupling change. To address the output voltage variation and efficiency drop caused by misa
Externí odkaz:
https://doaj.org/article/3ce1e6a268684389b778dd42c44b0223
Autor:
Christopher J. W. McClure, Kathleen E. Farley, Sarah E. Schulwitz, Jessi L. Brown, Jean-François Therrien, John A. Smallwood, Karl E. Miller, Karen Steenhof, Julie A. Heath
Publikováno v:
Ibis. 163:658-670
Autor:
Kathleen E. Farley, Claus Holzapfel, Anthony C. Cullen, Frank J. Gallagher, Susan Smith Pagano
Publikováno v:
Plant Ecology. 221:951-963
The functional role that invasive species occupy within their new range is of significant interest for those concerned about invasive species management. Of particular importance is the distribution mechanisms of invasive plants. Viburnum dilatatum a
Autor:
Agustin Casimiro-Garcia, Christophe Allais, Agnes Brennan, Chulho Choi, Gabriela Dower, Kathleen A. Farley, Margaret Fleming, Andrew Flick, Richard K. Frisbie, Justin Hall, David Hepworth, Hannah Jones, John D. Knafels, Steve Kortum, Frank E. Lovering, John P. Mathias, Sashi Mohan, Paul M. Morgan, Chuenlei Parng, Kevin Parris, Nick Pullen, Franklin Schlerman, John Stansfield, Joseph W. Strohbach, Felix F. Vajdos, Fabien Vincent, Hong Wang, Xiaolun Wang, Robert Webster, Stephen W. Wright
Publikováno v:
Journal of medicinal chemistry. 65(1)
A diaryl ketone series was identified as vanin-1 inhibitors from a high-throughput screening campaign. While this novel scaffold provided valuable probe
Autor:
Jiangli Yan, Armando Navarro-Vázquez, Ye Che, Veerabahu Shanmugasundaram, Dennis P. Anderson, Roberto R. Gil, Chris Limberakis, Michael J. Shapiro, Kathleen A. Farley
Publikováno v:
The Journal of Organic Chemistry. 84:4803-4813
Cyclic peptides have long tantalized drug designers with their potential ability to combine the best attributes of antibodies and small molecules. An ideal cyclic peptide drug candidate would be able to recognize a protein surface like an antibody wh