Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kathleen A, Lesich"'
Publikováno v:
Cytoskeleton (Hoboken, N.j.)
The mechanism that allows the axoneme of eukaryotic cilia and flagella to produce both helical and planar beating is an enduring puzzle. The nine outer doublets of eukaryotic cilia and flagella are arranged in a circle. Therefore, each doublet pair w
Publikováno v:
Cytoskeleton. 73:652-669
The eukaryotic flagellum is the organelle responsible for the propulsion of the male gamete in most animals. Without exception, sperm of all mammalian species use a flagellum for swimming. The mammalian sperm has a centrally located 9 + 2 arrangement
Publikováno v:
Cytoskeleton. 71:649-661
We report the results of an ultrastructural study of Triton X-100-extracted, Mg-adenosine triphosphate (ATP)-reactivated bull sperm. We utilized a rapid fixation method to look for differences in the flagellar apparatus that correlate to the state of
Publikováno v:
Cytoskeleton. 71:638-648
Sperm flagella derive their motive power from the motor protein dynein. In this study, we show that maintenance of the flagellar beat cycle in detergent-extracted bull sperm models is highly dependent on the ratio of Mg2+ to adenosine triphosphate (A
Publikováno v:
Cytoskeleton. 71:611-627
Calcium regulation of flagellar motility is the basis for chemotaxis, phototaxis, and hyperactivation responses in eukaryotic flagellates and spermatozoa. Ca2+ is the internal messenger for these responses, but the coupling between Ca2+ and the motor
Publikováno v:
Cellular and Molecular Bioengineering. 6:431-440
We utilize optical tweezers to examine displacements produced by small numbers of dynein motors located in situ on doublet microtubules from disintegrated mammalian sperm axonemes. In contrast with cytoplasmic dynein, we find that axonemal dynein is
Publikováno v:
Cytoskeleton (Hoboken, N.J.). 73(11)
The eukaryotic flagellum is the organelle responsible for the propulsion of the male gamete in most animals. Without exception, sperm of all mammalian species use a flagellum for swimming. The mammalian sperm has a centrally located 9 + 2 arrangement
Autor:
Charles B. Lindemann, Zhibing Zhang, Kathleen A. Lesich, Courtney B. Kelsch, Jerome F. Strauss, Kristen L. Ponichter
Publikováno v:
Biology of Reproduction. 82:736-744
The Spag16L gene codes for a protein that is localized to the central apparatus which is essential for normal sperm motility and male fertility. Sperm from mice homozygous for a targeted deletion of the Spag16L gene were examined to assess their flag
Publikováno v:
Journal of Cell Science. 123:519-528
The working mechanism of the eukaryotic flagellar axoneme remains one of nature's most enduring puzzles. The basic mechanical operation of the axoneme is now a story that is fairly complete; however, the mechanism for coordinating the action of the d
Publikováno v:
Biophysical Journal. 95(1):472-482
Adenosine diphosphate (ADP) is known to have interesting effects on flagellar motility. Permeabilized and reactivated bull sperm exhibit a marked reduction in beating frequency and a greatly increased beat amplitude in the presence of 1-4 mM ADP. In