Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kathleen, Wee"'
Autor:
Rebecca J. Deyell, Yaoqing Shen, Emma Titmuss, Katherine Dixon, Laura M. Williamson, Erin Pleasance, Jessica M. T. Nelson, Sanna Abbasi, Martin Krzywinski, Linlea Armstrong, Melika Bonakdar, Carolyn Ch’ng, Eric Chuah, Chris Dunham, Alexandra Fok, Martin Jones, Anna F. Lee, Yussanne Ma, Richard A. Moore, Andrew J. Mungall, Karen L. Mungall, Paul C. Rogers, Kasmintan A. Schrader, Alice Virani, Kathleen Wee, Sean S. Young, Yongjun Zhao, Steven J. M. Jones, Janessa Laskin, Marco A. Marra, Shahrad R. Rassekh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The role for routine whole genome and transcriptome analysis (WGTA) for poor prognosis pediatric cancers remains undetermined. Here, we characterize somatic mutations, structural rearrangements, copy number variants, gene expression, immuno-
Externí odkaz:
https://doaj.org/article/7e4974acf7f14999a67996f77a1aac77
Autor:
Irene S, Yu, Kathleen, Wee, Laura, Williamson, Emma, Titmuss, Jianghong, An, Sheida, Naderi-Azad, Corey, Metcalf, Stephen, Yip, Basil, Horst, Steven J M, Jones, Katherine, Paton, Brad H, Nelson, Marco, Marra, Janessa J, Laskin, Kerry J, Savage
Publikováno v:
Melanoma Research. 32:278-285
Uveal melanoma is the most common intraocular malignancy and has a poor prognosis compared to other melanoma subtypes with a median overall survival of 6-10 months. With immune checkpoint inhibitor therapy, either PD-1 inhibitor alone or combination
Autor:
Cameron J. Grisdale, Scott D. Brown, Kevin Y. Fan, Wei Zhang, Caralyn Reisle, Zoltan Bozoky, Robert A. Holt, Tariq Vira, Richard Corbett, Melika Bonakdar, My Linh Thibodeau, Kathleen Wee, Dean Cheng, Luka Culibrk, Marcus Carreira, David F. Schaeffer, Deirdre Weymann, Anna V. Tinker, Eric Y. Zhao, Michael K.C. Lee, Karen A. Gelmon, Karen Mungall, Richard A. Moore, Dean A. Regier, Daniel J. Renouf, Zusheng Zong, Reva Shenwai, Stephen Chia, Jahanshah Ashkani, Ana Fisic, Stephen Yip, Darryl D’Souza, Yussanne Ma, Daniel MacMillan, Erin Pleasance, Steve Bilobram, Alexandra Fok, Amir Muhammadzadeh, Jean-Michel Lavoie, Martin R. Jones, Hillary Pearson, Simon K. Chan, Balvir Deol, Steven J.M. Jones, Andrew J. Mungall, Mya Warren, Gregory A. Taylor, Elisa Majounie, Harwood H. Kwan, Eric Chuah, Howard John Lim, Sara Sadeghi, Dustin Bleile, Emma Titmuss, Reanne Bowlby, Anna Davies, Laura Williamson, Jessica Nelson, Caleb Choo, Jasleen K. Grewal, Katherine Dixon, Yongjun Zhao, Shehara Mendis, Yaoqing Shen, Janessa Laskin, Joanna M. Karasinska, Veronika Csizmok, Tina Wong, Sophie Sun, Kasmintan A. Schrader, Marco A. Marra
Publikováno v:
Nature Cancer. 1:452-468
Advanced and metastatic tumors with complex treatment histories drive cancer mortality. Here we describe the POG570 cohort, a comprehensive whole-genome, transcriptome and clinical dataset, amenable for exploration of the impacts of therapies on geno
Autor:
Michelle M Lissner, Brandon J Thomas, Kathleen Wee, Ann-Jay Tong, Tobias R Kollmann, Stephen T Smale
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132061 (2015)
A variety of age-related differences in the innate and adaptive immune systems have been proposed to contribute to the increased susceptibility to infection of human neonates and older adults. The emergence of RNA sequencing (RNA-seq) provides an opp
Externí odkaz:
https://doaj.org/article/64bbfa95ae97453eb86e3cd281e01255
Autor:
Cheryl Ho, Kathleen Wee, Laura Williamson, Daniel J. Renouf, Stephen Yip, Erin Pleasance, Martin R. Jones, Marco A. Marra, Elisa Majounie, Steven J.M. Jones, Janessa Laskin, Howard John Lim
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers worldwide and represents a heterogeneous group of tumors, the majority of which are treated with a combination of surgery, radiation, and chemotherapy. Fluoropyrimidine (
Autor:
Gregory A. Taylor, Emma Tittmus, D.J. Renouf, Kathleen Wee, Karen Mungall, Richard A. Moore, Yaoqing Shen, Lim Howard John, Veronika Csizmok, Alexandra Bohm, Caralyn Reisle, Steven J. M. Jones, Erin Pleasance, Janessa Laskin, Melika Bonakdar, Jessica Nelson, Marco Marra, Sophie Sun, Andrew J. Mungall, Eric Chuah, Balvir Deol, Laura Williamson, Martin Jones
Publikováno v:
Cancer Research. 81:98-98
Sequencing technology is increasingly essential in clinical cancer management. The majority of clinical cancer sequencing has focused on panel approaches, but recent trials have begun to report the use of transcriptome expression profiling to match p
Autor:
Erin, Pleasance, Emma, Titmuss, Laura, Williamson, Harwood, Kwan, Luka, Culibrk, Eric Y, Zhao, Katherine, Dixon, Kevin, Fan, Reanne, Bowlby, Martin R, Jones, Yaoqing, Shen, Jasleen K, Grewal, Jahanshah, Ashkani, Kathleen, Wee, Cameron J, Grisdale, My Linh, Thibodeau, Zoltan, Bozoky, Hillary, Pearson, Elisa, Majounie, Tariq, Vira, Reva, Shenwai, Karen L, Mungall, Eric, Chuah, Anna, Davies, Mya, Warren, Caralyn, Reisle, Melika, Bonakdar, Gregory A, Taylor, Veronika, Csizmok, Simon K, Chan, Zusheng, Zong, Steve, Bilobram, Amir, Muhammadzadeh, Darryl, D'Souza, Richard D, Corbett, Daniel, MacMillan, Marcus, Carreira, Caleb, Choo, Dustin, Bleile, Sara, Sadeghi, Wei, Zhang, Tina, Wong, Dean, Cheng, Scott D, Brown, Robert A, Holt, Richard A, Moore, Andrew J, Mungall, Yongjun, Zhao, Jessica, Nelson, Alexandra, Fok, Yussanne, Ma, Michael K C, Lee, Jean-Michel, Lavoie, Shehara, Mendis, Joanna M, Karasinska, Balvir, Deol, Ana, Fisic, David F, Schaeffer, Stephen, Yip, Kasmintan, Schrader, Dean A, Regier, Deirdre, Weymann, Stephen, Chia, Karen, Gelmon, Anna, Tinker, Sophie, Sun, Howard, Lim, Daniel J, Renouf, Janessa, Laskin, Steven J M, Jones, Marco A, Marra
Publikováno v:
Nature cancer. 1(4)
Advanced and metastatic tumors with complex treatment histories drive cancer mortality. Here we describe the POG570 cohort, a comprehensive whole-genome, transcriptome and clinical dataset, amenable for exploration of the impacts of therapies on geno
Publikováno v:
Chembiochem : a European journal of chemical biology. 19(19)
Aminoglycosides are a group of broad-spectrum antibiotics that have been used in the clinic for almost a century. The rapid spread of bacterial genes coding for aminoglycoside-modifying enzymes has, however, dramatically decreased the utility of amin
Autor:
Tobias R. Kollmann, Ann-Jay Tong, Brandon J. Thomas, Stephen T. Smale, Kathleen Wee, Michelle M. Lissner
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132061 (2015)
PloS one, vol 10, iss 7
PLoS ONE
PloS one, vol 10, iss 7
PLoS ONE
A variety of age-related differences in the innate and adaptive immune systems have been proposed to contribute to the increased susceptibility to infection of human neonates and older adults. The emergence of RNA sequencing (RNA-seq) provides an opp
Publikováno v:
Clinical and vaccine immunology : CVI. 21(3)
Robust CD8+T cell responses are essential for immune protection against intracellular pathogens. Using parenteral administration of ovalbumin (OVA) protein as a model antigen, the effect of the Toll-like receptor 9 (TLR9) agonist, CpG oligodeoxynucle