Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kathleen, Szczur"'
Autor:
Kathleen Szczur
Publikováno v:
Cell and Gene Therapy Insights. 5:1305-1310
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c30fb43ef6cd75a5cd362a53778b2b7f
https://doi.org/10.18609/cgti.2019.136
https://doi.org/10.18609/cgti.2019.136
Autor:
Anindya, Dasgupta, Stuart, Tinch, Kathleen, Szczur, Rebecca, Ernst, Nathaniel, Shryock, Courtney, Kaylor, Kendall, Lewis, Eric, Day, Timmy, Truong, William, Swaney
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2086
In clinical gene transfer applications, lentiviral vectors (LV) have rapidly become the primary means to achieve permanent and stable expression of a gene of interest or alteration of gene expression in target cells. This status can be attributed pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47b25798a49027f8b192f01446c19656
https://pubmed.ncbi.nlm.nih.gov/31707666
https://pubmed.ncbi.nlm.nih.gov/31707666
Autor:
Kendall Lewis, William Swaney, Nathaniel Shryock, Stuart Tinch, Anindya Dasgupta, Rebecca Ernst, Timmy Truong, Courtney Kaylor, Kathleen Szczur, Eric Day
Publikováno v:
Methods in Molecular Biology ISBN: 9781071601457
In clinical gene transfer applications, lentiviral vectors (LV) have rapidly become the primary means to achieve permanent and stable expression of a gene of interest or alteration of gene expression in target cells. This status can be attributed pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8fdf03f034e2aa5114d04a71718a218
https://doi.org/10.1007/978-1-0716-0146-4_3
https://doi.org/10.1007/978-1-0716-0146-4_3
Publikováno v:
Methods in Molecular Biology ISBN: 9781493990641
Lentiviral vectors have rapidly become a favorite tool for research and clinical gene transfer applications which seek to permanently introduce alterations in the genome. This status can be attributed primarily to their ability to transduce dividing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0eb9098c01765fc75e7fdd0eb21aa8
https://doi.org/10.1007/978-1-4939-9065-8_8
https://doi.org/10.1007/978-1-4939-9065-8_8
Autor:
Marie-Dominique Filippi, Rupali Sani Kumar, Ramesh C. Nayak, Rachna Raman, Kathleen Szczur, Jose A. Cancelas, Juying Xu, Sachin Kumar, Ashwini Hinge
Publikováno v:
Leukemia
Hematopoiesis is regulated by components of the microenvironment, so-called niche. Here, we show that p190-B GTPase-activating protein (p190-B) deletion in mice causes hematopoietic failure during ontogeny, in p190-B(-/-) fetal liver and bones, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdb11e7a50f6e611c9983012845c89c
http://europepmc.org/articles/PMC3919554
http://europepmc.org/articles/PMC3919554
Publikováno v:
Blood. 114:4527-4537
Neutrophil migration to sites of infection is the first line of cellular defense. A key event of migration is the maintenance of a polarized morphology, which is characterized by a single leading edge of filamentous actin and a contractile uropod dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da3050178959c4783536741affb3a02
https://doi.org/10.1182/blood-2008-12-195164
https://doi.org/10.1182/blood-2008-12-195164
Autor:
Deidre Daria, Marie Dominique Filippi, Haiming Xu, Satyam Eleswarapu, Hartmut Geiger, Jeffrey Settleman, Edward F. Srour, Kathleen Szczur, Yi Zheng, David A. Williams
Publikováno v:
Blood. 114:3557-3566
Hematopoietic stem cell (HSC) engraftment is a multistep process involving HSC homing to bone marrow, self-renewal, proliferation, and differentiation to mature blood cells. Here, we show that loss of p190-B RhoGTPase activating protein, a negative r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1190be4257e61b6e53fce85a714e0f79
https://doi.org/10.1182/blood-2009-02-205815
https://doi.org/10.1182/blood-2009-02-205815
Publikováno v:
Blood. 108:4205-4213
Neutrophil transmigration into tissue is a multiple-step process that results from a coordinated rearrangement of the cytoskeleton and adhesion complexes. Assembly and disassembly of actin and adhesion structures dictate motility behavior, while pola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fb337aed792431338e7880c1adc9f5
https://doi.org/10.1182/blood-2006-03-013789
https://doi.org/10.1182/blood-2006-03-013789
Publikováno v:
Blood. 109:1257-1264
Neutrophils are critical in the inflammatory process by moving rapidly to tissue sites of inflammation. Members of the small Rho GTPase family, Rac1, Rac2, CDC42, and RhoA, are central regulators of cell migration by cytoskeleton rearrangement. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a76435c61582a77347f078457e06bd
https://doi.org/10.1182/blood-2006-04-017731
https://doi.org/10.1182/blood-2006-04-017731
Publikováno v:
Inflammation. 19:529-541
Burn patients often experience a devastating inflammatory response to infection within the first two weeks after thermal injury. The inflammatory cytokines IL-6, TNF and IL-1 have been implicated in this condition but most studies have focused on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d759058592d3780399a610bdfcd8cfe
https://doi.org/10.1007/bf01539133
https://doi.org/10.1007/bf01539133