Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Kathleen, Lambein"'
Autor:
Hanne Vos, Kathleen Lambein, François Richard, Bram Mariën, Ines Nevelsteen, Kevin Punie, Hans Wildiers, Lieze Berben, Annouschka Laenen, Giuseppe Floris, Christine Desmedt, Ann Smeets
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-5 (2021)
Abstract The vast majority of studies investigating immune checkpoint inhibition (ICI) in patients with breast cancer have focused on triple-negative breast cancer (TNBC). In this study, we compared the tumor immune microenvironment (TIME) between TN
Externí odkaz:
https://doaj.org/article/8c78a70e9b4d4db798014a17106372d6
Autor:
Olivier De Wever, Hannelore Denys, Veronique Cocquyt, Marc Bracke, Christian P. Gespach, Philippe Valet, Catherine Muller, Camille Lehuédé, Dawn Maynard, Christian Vanhove, Jo Vandesompele, Pieter Mestdagh, Ridha Limame, Rudy Van Den Broecke, Geert Braems, Mieke Van Bockstal, Kathleen Lambein, An Hendrix, Lore Lapeire
Left panel: Graph representing proliferation rate of MCF-7-GFP and MCF-7-OSM cells in time (asterix indicates P = .068). Right upper panel: images of MCF-7-GFP and MCF-7-OSM aggregates embedded in type I collagen (scale bar is 100 µm). Right lower p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9317960ec89c7d68d332a4362de0bbac
https://doi.org/10.1158/0008-5472.22403472
https://doi.org/10.1158/0008-5472.22403472
Autor:
Olivier De Wever, Hannelore Denys, Veronique Cocquyt, Marc Bracke, Christian P. Gespach, Philippe Valet, Catherine Muller, Camille Lehuédé, Dawn Maynard, Christian Vanhove, Jo Vandesompele, Pieter Mestdagh, Ridha Limame, Rudy Van Den Broecke, Geert Braems, Mieke Van Bockstal, Kathleen Lambein, An Hendrix, Lore Lapeire
Supplemental materials and methods in addition to those mentioned in the manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e6bdd0d8967d41b4d220b24fb623cb
https://doi.org/10.1158/0008-5472.22403466
https://doi.org/10.1158/0008-5472.22403466
Autor:
Olivier De Wever, Hannelore Denys, Veronique Cocquyt, Marc Bracke, Christian P. Gespach, Philippe Valet, Catherine Muller, Camille Lehuédé, Dawn Maynard, Christian Vanhove, Jo Vandesompele, Pieter Mestdagh, Ridha Limame, Rudy Van Den Broecke, Geert Braems, Mieke Van Bockstal, Kathleen Lambein, An Hendrix, Lore Lapeire
Flow chart indicating CMCAAT prepared from 25 breast cancer patients and tested in the experimental conditions described throughout the article. OSM concentration was measured by ELISA for the samples indicated in bold type (see also figure 3C).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc089efd9e651a5b0e834b1fdf47e79
https://doi.org/10.1158/0008-5472.22403487.v1
https://doi.org/10.1158/0008-5472.22403487.v1
Autor:
Olivier De Wever, Hannelore Denys, Veronique Cocquyt, Marc Bracke, Christian P. Gespach, Philippe Valet, Catherine Muller, Camille Lehuédé, Dawn Maynard, Christian Vanhove, Jo Vandesompele, Pieter Mestdagh, Ridha Limame, Rudy Van Den Broecke, Geert Braems, Mieke Van Bockstal, Kathleen Lambein, An Hendrix, Lore Lapeire
Graphs representing relative mRNA levels of OSMR, LIFR, GP130 and STAT3 in MCF-7 and SKBR3 cells treated for 48h with control medium or rhOSM (2 ng/ml).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bab0b381ce5a3bf880916b1976a9abb
https://doi.org/10.1158/0008-5472.22403478.v1
https://doi.org/10.1158/0008-5472.22403478.v1
Autor:
Olivier De Wever, Hannelore Denys, Veronique Cocquyt, Marc Bracke, Christian P. Gespach, Philippe Valet, Catherine Muller, Camille Lehuédé, Dawn Maynard, Christian Vanhove, Jo Vandesompele, Pieter Mestdagh, Ridha Limame, Rudy Van Den Broecke, Geert Braems, Mieke Van Bockstal, Kathleen Lambein, An Hendrix, Lore Lapeire
IDCA: invasive ductal carcinoma, Max diam: maximal diameter, ER: estrogen receptor, PR: progesterone receptor, Pos LN: positive lymph nodes, LVI: lymphovascular invasion, BMI: body mass index.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d85c4384fbb17ebb0c0933f51d61dc9
https://doi.org/10.1158/0008-5472.22403457.v1
https://doi.org/10.1158/0008-5472.22403457.v1
Autor:
Olivier De Wever, Hannelore Denys, Veronique Cocquyt, Marc Bracke, Christian P. Gespach, Philippe Valet, Catherine Muller, Camille Lehuédé, Dawn Maynard, Christian Vanhove, Jo Vandesompele, Pieter Mestdagh, Ridha Limame, Rudy Van Den Broecke, Geert Braems, Mieke Van Bockstal, Kathleen Lambein, An Hendrix, Lore Lapeire
Upper panels: Western blot analysis of E-cadherin, beta-catenin, vimentin, fibronectin, pancytokeratin and estrogen receptor alpha (ERα). Left panel: MCF-7 cells treated for 48h with control medium or CMCAAT. Right panel: MCF-7 cells stably transfec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcdbbada29a48c7ede052f01ade0ccc
https://doi.org/10.1158/0008-5472.22403484.v1
https://doi.org/10.1158/0008-5472.22403484.v1
Autor:
Olivier De Wever, Hannelore Denys, Veronique Cocquyt, Marc Bracke, Christian P. Gespach, Philippe Valet, Catherine Muller, Camille Lehuédé, Dawn Maynard, Christian Vanhove, Jo Vandesompele, Pieter Mestdagh, Ridha Limame, Rudy Van Den Broecke, Geert Braems, Mieke Van Bockstal, Kathleen Lambein, An Hendrix, Lore Lapeire
Upper left panel: Image representing a protein array of 507 proteins used for detection of soluble factors present in a mixture of CMCAAT from two patients. Each protein is spotted in duplicate. The boxes show the positive controls. The brackets indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2f86b9b13bbbaeb4c3ba4f1efb48db
https://doi.org/10.1158/0008-5472.22403481.v1
https://doi.org/10.1158/0008-5472.22403481.v1
Autor:
Hanne Vos, Kathleen Lambein, François Richard, Ines Nevelsteen, Ayse Bassez, Diether Lambrechts, Kevin Punie, Hans Wildiers, Giuseppe Floris, Christine Desmedt, Ann Smeets
Publikováno v:
Cancer Research. 82:P2-08
Intro: Despite the growing success of immune checkpoint blockade in BC, the underlying mechanisms of response or resistance to these treatments is still poorly understood. We recently conducted a window-of-opportunity study (BioKey) including 54 pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4002b56da20fd5609e01d384fea08c9d
https://doi.org/10.1158/1538-7445.sabcs21-p2-08-23
https://doi.org/10.1158/1538-7445.sabcs21-p2-08-23
Autor:
Ximena Baez Navarro, Mieke Rosalie van Bockstal, Diënna Nawawi, Glenn Broeckx, Cecile Colpaert, Shusma Charlane Doebar, Marieke C.H. Hogenes, Esther Koop, Kathleen Lambein, Dieter J.E. Peeters, Renata Sinke, Johannes Bastiaan van Brakel, José van der Starre-Gaal, Bert Van der Vegt, Koen Van de Vijver, Celien P.H. Vreuls, Willem Vreuls, Pieter Westenend, Carolien van Deurzen
The classification of Human Epidermal Growth Factor Receptor 2 (HER2) expression is optimized to detect HER2-amplified breast cancer (BC). However, novel HER2-targeting agents are also effective for BCs with low levels of HER2. This raises the questi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e99f29a9a00257dde6327ae25e241ec5
https://doi.org/10.21203/rs.3.rs-1807403/v1
https://doi.org/10.21203/rs.3.rs-1807403/v1