Circumsporozoite Protein of Plasmodium berghei- and George Baker Virus A-Derived Peptides Trigger Efficient Cell Internalization of Bioconjugates and Functionalized Poly(ethylene glycol)-b-poly(benzyl malate)-Based Nanoparticles in Human Hepatoma Cells

Autor: Elise Vène, Kathleen Jarnouen, Catherine Ribault, Manuel Vlach, Yann Verres, Mickaël Bourgeois, Nicolas Lepareur, Sandrine Cammas-Marion, Pascal Loyer

Publikováno v: Pharmaceutics, Vol 14, Iss 4, p 804 (2022)

In order to identify the peptides, selected from the literature, that exhibit the strongest tropism towards human hepatoma cells, cell uptake assays were performed using biotinylated synthetic peptides bound to fluorescent streptavidin or engrafted o

Externí odkaz: https://doaj.org/article/a6bd928abdf74b0d8bb87eceb2b43b2a

Circumsporozoite Protein of

Autor: Elise, Vène, Kathleen, Jarnouen, Catherine, Ribault, Manuel, Vlach, Yann, Verres, Mickaël, Bourgeois, Nicolas, Lepareur, Sandrine, Cammas-Marion, Pascal, Loyer

Publikováno v: Pharmaceutics. 14(4)

In order to identify the peptides, selected from the literature, that exhibit the strongest tropism towards human hepatoma cells, cell uptake assays were performed using biotinylated synthetic peptides bound to fluorescent streptavidin or engrafted o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c0638ebf43c61cad60f0e6a6729e1d75
https://pubmed.ncbi.nlm.nih.gov/35456637

Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells

Autor: Michelle Pinault, Laure Peyta, Kathleen Jarnouen, Stephan Chevalier, Cyrille Guimaraes, Grant M. Hatch, Pascal Loyer, Jean-François Dumas, Jean-Paul Pais de Barros, François Maillot, Stéphane Servais

Publikováno v: Biochimica biophysica acta (BBA)-Bioenergetics
Biochimica biophysica acta (BBA)-Bioenergetics, Elsevier, 2016, 1857 (4), pp.443-453. ⟨10.1016/j.bbabio.2016.01.002⟩
Biochimica biophysica acta (BBA)-Bioenergetics, 2016, 1857 (4), pp.443-453. ⟨10.1016/j.bbabio.2016.01.002⟩
BBA-Bioenergetics
BBA-Bioenergetics, Elsevier, 2016, 1857 (4), pp.443-453. 〈10.1016/j.bbabio.2016.01.002〉

International audience; Cardiolipin (CL) is a unique mitochondrial phospholipid potentially affecting many aspects of mitochondrial function/processes, i.e. energy production through oxidative phosphorylation. Most data focusing on implication of CL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d78bb82c14e9350daeb45d220a652b
https://doi.org/10.1016/j.bbabio.2016.01.002

Opsonisation of nanoparticles prepared from poly(β-hydroxybutyrate) and poly(trimethylene carbonate)-b-poly(malic acid) amphiphilic diblock copolymers: Impact on the in vitro cell uptake by primary human macrophages and HepaRG hepatoma cells

Autor: Ghislaine Barouti, Kathleen Jarnouen, Claudine Rauch, Sophie M. Guillaume, Thomas Gicquel, Sandrine Cammas-Marion, Pascal Loyer, Elise Vene, Catherine Ribault

Publikováno v: International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2016, 513 (1-2), pp.438--452. ⟨10.1016/j.ijpharm.2016.09.048⟩
International Journal of Pharmaceutics, 2016, 513 (1-2), pp.438--452. ⟨10.1016/j.ijpharm.2016.09.048⟩

International audience; The present work reports the investigation of the biocompatibility, opsonisation and cell uptake by human primary macrophages and HepaRG cells of nanoparticles (NPs) formulated from poly(β-malic acid)-b-poly(β-hydroxybutyrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e674cf9c7095027506b98ba92da83850
https://pubmed.ncbi.nlm.nih.gov/27640247

Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia

Autor: Pascal Loyer, Grant M. Hatch, Michelle Pinault, Stephan Chevalier, Cyrille Guimaraes, Kathleen Jarnouen, Laure Peyta, Cédric Coulouarn, François Maillot, Stéphane Servais, Caroline Goupille, Jean-Paul Pais de Barros, Jean-François Dumas

Publikováno v: BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2015, 1851 (11), pp.1490-1500. ⟨10.1016/j.bbalip.2015.08.008⟩
BBA-Biochimica et Biophysica Acta, 2015, 1851 (11), pp.1490-1500. ⟨10.1016/j.bbalip.2015.08.008⟩
BBA-Biochimica et Biophysica Acta, Elsevier, 2015, 1851 (11), pp.1490-1500. 〈10.1016/j.bbalip.2015.08.008〉

International audience; Cardiolipin (CL) content accumulation leads to an increase in energy wasting in liver mitochondria in a rat model of cancer cachexia in which tumor necrosis factor alpha (TNFα) is highly expressed. In this study we investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56df6a0e376347cc69f0eda6048633fc
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01197346