Zobrazeno 1 - 10 of 113 pro vyhledávání: '"Kathleen, Conway"'
1
Akademický článek
Prognostic significance of RNA-based TP53 pathway function among estrogen receptor positive and negative breast cancer cases
Autor: Amber N. Hurson, Mustapha Abubakar, Alina M. Hamilton, Kathleen Conway, Katherine A. Hoadley, Michael I. Love, Andrew F. Olshan, Charles M. Perou, Montserrat Garcia-Closas, Melissa A. Troester
Publikováno v: npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract TP53 and estrogen receptor (ER) are essential in breast cancer development and progression, but TP53 status (by DNA sequencing or protein expression) has been inconsistently associated with survival. We evaluated whether RNA-based TP53 class
Externí odkaz: https://doaj.org/article/529696f68a5e470a94d527f453ee537a
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3
Akademický článek
Comparison of community pathologists with expert dermatopathologists evaluating Breslow thickness and histopathologic subtype in a large international population-based study of melanoma
Autor: Joseph Michael Yardman-Frank, MPH, Baillie Bronner, BA, Stefano Rosso, PhD, Lynn From, MD, Klaus Busam, MD, Pam Groben, MD, Paul Tucker, MD, Anne Cust, PhD, Bruce Armstrong, MD, Anne Kricker, PhD, Loraine Marrett, PhD, Hoda Anton-Culver, PhD, Stephen Gruber, MD, Rick Gallagher, MA, Roberto Zanetti, MD, Lidia Sacchetto, PhD, Terry Dwyer, MD, Alison Venn, PhD, Irene Orlow, PhD, Peter Kanetsky, PhD, Li Luo, PhD, Nancy Thomas, MD, Colin Begg, PhD, Marianne Berwick, PhD, MPH, Marianne Berwick, MPH, PhD, Irene Orlow, PhD, MS, Klaus J. Busam, MD, Isidora Autuori, MS, Pampa Roy, PhD, Anne Reiner, MS, Tawny W. Boyce, MPH, Anne E. Cust, PhD, Bruce K. Armstrong, MD, PhD, Alison Venn, Terence Dwyer, Paul Tucker, Richard P. Gallagher, MA, Loraine D. Marrett, PhD, Stefano Rosso, MD, MSc, Stephen B. Gruber, MD, MPH, PhD, Joseph D. Bonner, PhD, Nancy E. Thomas, MD, PhD, Kathleen Conway, PhD, David W. Ollila, MD, Pamela A. Groben, MD, Sharon N. Edmiston, BA, Honglin Hao, Eloise Parrish, MSPH, Jill S. Frank, MS, David C. Gibbs, BS, Timothy R. Rebbeck, PD, Peter A. Kanetsky, MPH, PhD, Julia Lee Taylor, PhD, Sasha Madronich, PhD
Publikováno v: JAAD International, Vol 4, Iss , Pp 25-27 (2021)
Externí odkaz: https://doaj.org/article/0d03a07d28c54b7781694e8bda8cf0fb
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4
Akademický článek
Reproductive characteristics are associated with gene-specific promoter methylation status in breast cancer
Autor: Lauren E. McCullough, Lindsay J. Collin, Kathleen Conway, Alexandra J. White, Yoon Hee Cho, Sumitra Shantakumar, Mary Beth Terry, Susan L. Teitelbaum, Alfred I. Neugut, Regina M. Santella, Jia Chen, Marilie D. Gammon
Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Reproductive characteristics are well-established risk factors for breast cancer, but the underlying mechanisms are not fully resolved. We hypothesized that altered DNA methylation, measured in tumor tissue, could act in concert w
Externí odkaz: https://doaj.org/article/28bbfdee2aa14652add4cca6ef8d7c4b
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6
Akademický článek
Reproductive characteristics modify the association between global DNA methylation and breast cancer risk in a population-based sample of women.
Autor: Lindsay J Collin, Lauren E McCullough, Kathleen Conway, Alexandra J White, Xinran Xu, Yoon Hee Cho, Sumitra Shantakumar, Susan L Teitelbaum, Alfred I Neugut, Regina M Santella, Jia Chen, Marilie D Gammon
Publikováno v: PLoS ONE, Vol 14, Iss 2, p e0210884 (2019)
DNA methylation has been implicated in breast cancer aetiology, but little is known about whether reproductive history and DNA methylation interact to influence carcinogenesis. This study examined modification of the association between global DNA me
Externí odkaz: https://doaj.org/article/a6b923cb30364faea8a08aadcf90469f
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8
Data from Altered-Function p53 Missense Mutations Identified in Breast Cancers Can Have Subtle Effects on Transactivation
Autor: Michael A. Resnick, Lin Wu, Lisa A. Carey, Sharon Edmiston, Kathleen Conway, Alberto Inga, Jennifer J. Jordan
Mutations of the sequence-specific master regulator p53 that alter transactivation function from promoter response elements (RE) could result in changes in the strength of gene activation or spectra of genes regulated. Such mutations in this tumor su
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9f4c462c38f2097a55b9871ac56c69
https://doi.org/10.1158/1541-7786.c.6542128.v1
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10
Supplementary Figures S1-3, Tables S1-4 from Racial Variation in Breast Tumor Promoter Methylation in the Carolina Breast Cancer Study
Autor: Theresa Swift-Scanlan, Ryan May, Eloise A. Parrish, Brionna Y. Hair, Pei Fen Kuan, Christopher Bryant, Chiu-Kit Tse, Sharon N. Edmiston, Kathleen Conway
Supplementary Figures S1-3, Tables S1-4. Supplemental Figure S1. Racial differences in breast tumor methylation at candidate CpG probes when race is self-reported or defined by AIMs markers. Supplemental Figure S2. Methylation detected at KCNK4 and D
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0f7255ad19c29e20cb16b1c2d23ea2
https://doi.org/10.1158/1055-9965.22436503.v1
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