Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Kathie-Anne Walters"'
Autor:
Luca T. Giurgea, Jae-Keun Park, Kathie-Anne Walters, Kelsey Scherler, Adriana Cervantes-Medina, Ashley Freeman, Luz Angela Rosas, John C. Kash, Jeffery K. Taubenberger, Matthew J. Memoli
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-7 (2021)
Abstract Despite the importance of immunity against neuraminidase (NA), NA content and immunogenicity are neglected in current influenza vaccines. To address this, a recombinant N1/N2 NA vaccine (NAV) was developed. Stability assays were used to dete
Externí odkaz:
https://doaj.org/article/e4321783a19a4370b86945991fe73acd
Autor:
Kathie-Anne Walters, Ruoqing Zhu, Michael Welge, Kelsey Scherler, Jae-Keun Park, Zainab Rahil, Hao Wang, Loretta Auvil, Colleen Bushell, Min Young Lee, David Baxter, Tyler Bristol, Luz Angela Rosas, Adriana Cervantes-Medina, Lindsay Czajkowski, Alison Han, Matthew J. Memoli, Jeffery K. Taubenberger, John C. Kash
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT In this study, we examined the relationships between anti-influenza virus serum antibody titers, clinical disease, and peripheral blood leukocyte (PBL) global gene expression during presymptomatic, acute, and convalescent illness in 83 parti
Externí odkaz:
https://doaj.org/article/f9790b867e4e4a31baa6bbf277ba8385
Autor:
Anne Grosse-Wilde, Aymeric Fouquier d'Hérouël, Ellie McIntosh, Gökhan Ertaylan, Alexander Skupin, Rolf E Kuestner, Antonio del Sol, Kathie-Anne Walters, Sui Huang
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126522 (2015)
Breast cancer stem cells (CSCs) are thought to drive recurrence and metastasis. Their identity has been linked to the epithelial to mesenchymal transition (EMT) but remains highly controversial since--depending on the cell-line studied--either epithe
Externí odkaz:
https://doaj.org/article/d166ca2631a6496893c4d88754c93f41
Autor:
Li Qi, Lindsey M. Pujanauski, A. Sally Davis, Louis M. Schwartzman, Daniel S. Chertow, David Baxter, Kelsey Scherler, Kevan L. Hartshorn, Richard D. Slemons, Kathie-Anne Walters, John C. Kash, Jeffery K. Taubenberger
Publikováno v:
mBio, Vol 5, Iss 6 (2014)
ABSTRACT Zoonotic avian influenza virus infections may lead to epidemics or pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its H1 hemagglutinin was identified as a key mammalian virulence factor. A chimeric
Externí odkaz:
https://doaj.org/article/749985f15a0e40c3b186b8f65080019d
Autor:
Kathie-Anne Walters, Rachael Olsufka, Rolf E Kuestner, Ji Hoon Cho, Hong Li, Gregory A Zornetzer, Kai Wang, Shawn J Skerrett, Adrian Ozinsky
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62412 (2013)
Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical inflammatory mediators, including IL1-β and TNF-α, during early infection has led to the suggestion
Externí odkaz:
https://doaj.org/article/10a7b448b18645ae8933f90e24e957df
Autor:
John C. Kash, Kathie-Anne Walters, A. Sally Davis, Aline Sandouk, Louis M. Schwartzman, Brett W. Jagger, Daniel S. Chertow, Li Qi, Rolf E. Kuestner, Adrian Ozinsky, Jeffery K. Taubenberger
Publikováno v:
mBio, Vol 2, Iss 5 (2011)
ABSTRACT Secondary bacterial infections increase disease severity of influenza virus infections and contribute greatly to increased morbidity and mortality during pandemics. To study secondary bacterial infection following influenza virus infection,
Externí odkaz:
https://doaj.org/article/b60597ee78454a638166901323a25cac
Autor:
Deborah L Diamond, Andrew J Syder, Jon M Jacobs, Christina M Sorensen, Kathie-Anne Walters, Sean C Proll, Jason E McDermott, Marina A Gritsenko, Qibin Zhang, Rui Zhao, Thomas O Metz, David G Camp, Katrina M Waters, Richard D Smith, Charles M Rice, Michael G Katze
Publikováno v:
PLoS Pathogens, Vol 6, Iss 1, p e1000719 (2010)
Proteomic and lipidomic profiling was performed over a time course of acute hepatitis C virus (HCV) infection in cultured Huh-7.5 cells to gain new insights into the intracellular processes influenced by this virus. Our proteomic data suggest that HC
Externí odkaz:
https://doaj.org/article/ba61ce4400a44ab3b967b7abeea79649
Autor:
Sharon Lederer, David Favre, Kathie-Anne Walters, Sean Proll, Bittoo Kanwar, Zeljka Kasakow, Carole R Baskin, Robert Palermo, Joseph M McCune, Michael G Katze
Publikováno v:
PLoS Pathogens, Vol 5, Iss 2, p e1000296 (2009)
Simian immunodeficiency virus (SIV) infection leads to AIDS in experimentally infected macaques, whereas natural reservoir hosts exhibit limited disease and pathology. It is, however, unclear how natural hosts can sustain high viral loads, comparable
Externí odkaz:
https://doaj.org/article/7258cd41b89e431784e5db74e54e4d3e
Autor:
Michael A Joyce, Kathie-Anne Walters, Sue-Ellen Lamb, Mathew M Yeh, Lin-Fu Zhu, Norman Kneteman, Jason S Doyle, Michael G Katze, D Lorne Tyrrell
Publikováno v:
PLoS Pathogens, Vol 5, Iss 2, p e1000291 (2009)
Hepatitis C virus (HCV) is a blood-borne pathogen and a major cause of liver disease worldwide. Gene expression profiling was used to characterize the transcriptional response to HCV H77c infection. Evidence is presented for activation of innate anti
Externí odkaz:
https://doaj.org/article/cacd4acb73fb43d1a8a778e72fdf1850
Autor:
Kathie-Anne Walters, Andrew J Syder, Sharon L Lederer, Deborah L Diamond, Bryan Paeper, Charles M Rice, Michael G Katze
Publikováno v:
PLoS Pathogens, Vol 5, Iss 1, p e1000269 (2009)
The mechanisms of liver injury associated with chronic HCV infection, as well as the individual roles of both viral and host factors, are not clearly defined. However, it is becoming increasingly clear that direct cytopathic effects, in addition to i
Externí odkaz:
https://doaj.org/article/043b8f260cfd40e3be4ba75102e49306