Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Katheryn Meek"'
Autor:
Katheryn Meek, Ya-Ting Yang, Marilia Takada, Maciej Parys, Marlee Richter, Alexander I. Engleberg, Tuddow Thaiwong, Rachel L. Griffin, Peter Z. Schall, Alana J. Kramer, Vilma Yuzbasiyan-Gurkan
Publikováno v:
Genes, Vol 13, Iss 10, p 1693 (2022)
Bernese mountain dogs (BMDs), have an overall cancer incidence of 50%, half of which is comprised of an otherwise rare tumor, histiocytic sarcoma (HS). While recent studies have identified driver mutations in the MAPK pathway, identification of key p
Externí odkaz:
https://doaj.org/article/0bb0654aac1140199e74801c7b4ad017
Autor:
Satish K. Tadi, Carine Tellier-Lebègue, Clément Nemoz, Pascal Drevet, Stéphane Audebert, Sunetra Roy, Katheryn Meek, Jean-Baptiste Charbonnier, Mauro Modesti
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 541-555 (2016)
In mammalian cells, classical non-homologous end joining (c-NHEJ) is critical for DNA double-strand break repair induced by ionizing radiation and during V(D)J recombination in developing B and T lymphocytes. Recently, PAXX was identified as a c-NHEJ
Externí odkaz:
https://doaj.org/article/c861e7cc7c714c09a07a270f4bfd07e7
Autor:
Davide Normanno, Aurélie Négrel, Abinadabe J de Melo, Stéphane Betzi, Katheryn Meek, Mauro Modesti
Publikováno v:
eLife, Vol 6 (2017)
XRCC4 and DNA Ligase 4 (LIG4) form a tight complex that provides DNA ligase activity for classical non-homologous end joining (the predominant DNA double-strand break repair pathway in higher eukaryotes) and is stimulated by XLF. Independently of LIG
Externí odkaz:
https://doaj.org/article/25865395ffa34e55964879d1f42c49a0
Autor:
Pauline Douglas, Ruiqiong Ye, Laura Trinkle‑Mulcahy, Jessica A. Neal, Veerle De Wever, Nick A. Morrice, Katheryn Meek, Susan P. Lees‑Miller
Publikováno v:
Bioscience Reports, Vol 34, Iss 3, p e00113 (2014)
The protein kinase activity of the DNA-PKcs (DNA-dependent protein kinase catalytic subunit) and its autophosphorylation are critical for DBS (DNA double-strand break) repair via NHEJ (non-homologous end-joining). Recent studies have shown that deple
Externí odkaz:
https://doaj.org/article/fc06bf56cbc94c20abed4a3a060d32c0
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67403 (2013)
Potential roles of the abasic site lyase activity associated with AlkB homolog 1 (ALKBH1) were assessed by studies focusing on the two cellular processes that create abasic sites as intermediates: base excision repair and class switch recombination.
Externí odkaz:
https://doaj.org/article/b6f16e4de5f54e2ca7d750f7065bfd15
Autor:
Thomas Helleday, Katheryn Meek, Benedikt M. Kessler, Freddie C. Hamdy, Huahao Shen, Xinming Song, Joanna McGouran, Oliver Mortusewicz, Zhengqiang Bao, Jessica A. Neal, Annette L. Medhurst, Zhihui Chen, Songmin Ying
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63046f27f2ed54402fd23949fa76cd98
https://doi.org/10.1158/0008-5472.22411764.v1
https://doi.org/10.1158/0008-5472.22411764.v1
Autor:
Thomas Helleday, Katheryn Meek, Benedikt M. Kessler, Freddie C. Hamdy, Huahao Shen, Xinming Song, Joanna McGouran, Oliver Mortusewicz, Zhengqiang Bao, Jessica A. Neal, Annette L. Medhurst, Zhihui Chen, Songmin Ying
A series of critical pathways are responsible for the detection, signaling, and restart of replication forks that encounter blocks during S-phase progression. Small base lesions may obstruct replication fork progression and processing, but the link b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::361d727bfa99010c57d5878fb42ab6d2
https://doi.org/10.1158/0008-5472.c.6508290.v1
https://doi.org/10.1158/0008-5472.c.6508290.v1
Autor:
Thomas Helleday, Katheryn Meek, Benedikt M. Kessler, Freddie C. Hamdy, Huahao Shen, Xinming Song, Joanna McGouran, Oliver Mortusewicz, Zhengqiang Bao, Jessica A. Neal, Annette L. Medhurst, Zhihui Chen, Songmin Ying
Supplementary Figures. Sup. Fig. 1: Recuirtment of XRCC1 to stalled DNA replication forks is prevented by CtIP. Sup. Fig. 2: CK2 actiivty is required for stabilization of XRCC1 protein and its recuirtment to stalled forks. Sup. Fig. 3: Interaction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bf44daa454108d34aa053e4f9bf6ae
https://doi.org/10.1158/0008-5472.22411761
https://doi.org/10.1158/0008-5472.22411761
Autor:
Susan M. Bailey, Robert L. Ullrich, Katheryn Meek, Susan P. Lees-Miller, Evelin Schrock, Tanja Hardt, Brian Ponnaiya, Rebekah Klingler, Eli S. Williams
Supplementary Table 2 from Telomere Dysfunction and DNA-PKcs Deficiency: Characterization and Consequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb619b67ae8a1a2c7abd1d3a01ee724
https://doi.org/10.1158/0008-5472.22380270.v1
https://doi.org/10.1158/0008-5472.22380270.v1
Autor:
Susan M. Bailey, Robert L. Ullrich, Katheryn Meek, Susan P. Lees-Miller, Evelin Schrock, Tanja Hardt, Brian Ponnaiya, Rebekah Klingler, Eli S. Williams
Supplementary Table 1 from Telomere Dysfunction and DNA-PKcs Deficiency: Characterization and Consequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af335de12a021ae79d388cb60ccb6fce
https://doi.org/10.1158/0008-5472.22380273.v1
https://doi.org/10.1158/0008-5472.22380273.v1