Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Katheryn Marie Stanford"'
Autor:
Hari Krishna Santhapuram, Iontcho Radoslavov Vlahov, Paul J. Kleindl, Stephen J. Howard, Christopher P. Leamon, Katheryn Marie Stanford
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(19)
An efficient synthesis of the folate receptor (FR) targeting conjugate EC145 is described. EC145 is a water soluble derivative of the vitamin folic acid and the potent cytotoxic agent, desacetylvinblastine monohydrazide. Both molecules are connected
Autor:
Iontcho Radoslavov Vlahov, Christopher P. Leamon, Katheryn Marie Stanford, Yu Wang, Hari Krishna Santhapuram, Allen Ritter, Le-Cun Xu, Paul J. Kleindl, Michael Groaning, Fei You
Publikováno v:
Cancer Research. 71:3259-3259
The tubulysins are members of a new class of natural products isolated from myxobacterial species.[1] As cytoskeleton interacting agents, the tubulysins are mitotic poisons that inhibit tubulin polymerization and lead to cell cycle arrest and apoptos