Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Katheryn A. Resing"'
Autor:
Katheryn A. Resing, Kevin M. Sours, Olayinka A. Oyeyemi, Judith P. Klinman, Natalie G. Ahn, Thomas Lee, Amnon Kohen
Publikováno v:
Biochemistry
The role of protein motions in enzymatic catalysis is a research area of great interest where much remains to be understood (e.g., refs (1−4)). Examining the similarities and differences in the dynamical features of enzyme homologues that catalyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab6496d14d3df8375fc9821137031c3
https://doi.org/10.1021/bi200640s
https://doi.org/10.1021/bi200640s
Autor:
Karen Meyer-Arendt, William M. Old, Katheryn A. Resing, Kutralanathan Renganathan, Stephane Houel, Brian Eichelberger, Natalie G. Ahn
Publikováno v:
Journal of Proteome Research
When analyzing proteins in complex samples using tandem mass spectrometry of peptides generated by proteolysis, the inference of proteins can be ambiguous, even with well-validated peptides. Unresolved questions include whether to show all possible p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806428ba4f0061c0f140df73f4d62a6c
http://europepmc.org/articles/PMC3167374
http://europepmc.org/articles/PMC3167374
Autor:
Wilas Nirunsuksiri, William M. Old, Sudeshna M. Chatterjea, Philip Fleckman, Katheryn A. Resing
Publikováno v:
Journal of Dermatological Science. 61:51-59
In normal mammalian epidermis, cell division and expression of keratins K5/K14 in the basal layer is followed by K1/K10, the keratin bundling protein filaggrin, and cornified envelope proteins such as involucrin and loricrin [1,2]. However, hyperprol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158594af47de43627a350c4553e24a28
https://doi.org/10.1016/j.jdermsci.2010.11.003
https://doi.org/10.1016/j.jdermsci.2010.11.003
Autor:
Olayinka A. Oyeyemi, Kevin M. Sours, Natalie G. Ahn, Judith P. Klinman, Thomas Lee, Katheryn A. Resing
Publikováno v:
Proceedings of the National Academy of Sciences. 107:10074-10079
We report hydrogen deuterium exchange by mass spectrometry (HDX-MS) as a function of temperature in a thermophilic dihydrofolate reductase from Bacillus stearothermophilus (Bs-DHFR). Protein stability, probed with circular dichroism, established an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1429d4823274c1c9329138c5f67e0b9e
https://doi.org/10.1073/pnas.1003678107
https://doi.org/10.1073/pnas.1003678107
Autor:
Yukihito Kabuyama, Kirsi Polvinen, Paul D. Templeton, Natalie G. Ahn, Eric S. Witze, James E. Fitzpatrick, Elizabeth S. Litman, Stephen J. Langer, Sandra I. Metzner, Gretchen M. Argast, Daniel Chan, Marcelo C. Sousa, Katheryn A. Resing, Yiqun G. Shellman, John B. Shabb
Publikováno v:
Molecular & Cellular Proteomics : MCP
RhoA controls changes in cell morphology and invasion associated with cancer phenotypes. Cell lines derived from melanoma tumors at varying stages revealed that RhoA is selectively activated in cells of metastatic origin. We describe a functional pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15956898d381afa75d385b56b018ea92
https://doi.org/10.1074/mcp.m900178-mcp200
https://doi.org/10.1074/mcp.m900178-mcp200
Publikováno v:
Protein Science. 9:170-179
High mobility group (HMG) proteins 14 and 17 are nonhistone nuclear proteins that have been implicated in control of transcription and chromatin structure. To examine the posttranslational modifications of HMG-14 and -17 in vivo, HMG proteins were pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79b24f5f44539fa92877d7e619eba17
https://doi.org/10.1110/ps.9.1.170
https://doi.org/10.1110/ps.9.1.170
Autor:
Xuedong Liu, William M. Old, Wei Wang, Natalie G. Ahn, Yuefeng Gao, Katheryn A. Resing, Yuting Yang, Ming Lei, Quanbin Xu, Songcheng Zhu, Feng Wang
Publikováno v:
Journal of Cellular and Molecular Medicine
Mps1 is one of the several essential kinases whose activation is required for robust mitotic spindle checkpoint signalling. The activity of Mps1 is tightly regulated and increases dramatically during mitosis or in response to spindle damage. To under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a55d6c4b3e0ea945455073844cd130b
https://doi.org/10.1111/j.1582-4934.2008.00605.x
https://doi.org/10.1111/j.1582-4934.2008.00605.x
Publikováno v:
Nature Methods. 4:798-806
Post-translational modifications of proteins control many biological processes, and examining their diversity is critical for understanding mechanisms of cell regulation. Mass spectrometry is a fundamental tool for detecting and mapping covalent modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c261dd2b798c704e1f3aec8c8f8eac8
https://doi.org/10.1038/nmeth1100
https://doi.org/10.1038/nmeth1100
Autor:
Natalie G. Ahn, Krzysztof J. Cios, Katheryn A. Resing, Kevin G. Pierce, Chia-Yu Yen, Karen Meyer-Arendt, Robert Brown, Shaojun Sun, Brian Eichelberger, William M. Old
Publikováno v:
Molecular & Cellular Proteomics. 6:1-17
A major limitation in identifying peptides from complex mixtures by shotgun proteomics is the ability of search programs to accurately assign peptide sequences using mass spectrometric fragmentation spectra (MS/MS spectra). Manual analysis is used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205761d0d1301a55dc13376cff524242
https://doi.org/10.1074/mcp.m600320-mcp200
https://doi.org/10.1074/mcp.m600320-mcp200
Publikováno v:
Current Opinion in Structural Biology. 16:686-692
The allosteric regulation of protein kinases serves as an efficient strategy for molecular communication, event coupling and interconversion between catalytic states. Recent co-crystal structures have revealed novel ways in which kinases control acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3858b00fe14b50fcc7eea50d1bbb16be
https://doi.org/10.1016/j.sbi.2006.10.011
https://doi.org/10.1016/j.sbi.2006.10.011