Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katherine Zimmel"'
Autor:
Connor P. Dolan, Tae-Jung Yang, Katherine Zimmel, Felisha Imholt, Osama Qureshi, Alyssa Falck, Joshua Gregory, Macie Mayes, Kayla Ritchie, Hannah Koester, Benjamin Daniel, Mingquan Yan, Ling Yu, Larry J. Suva, Dana Gaddy, Lindsay A. Dawson, Ken Muneoka, Regina Brunauer
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Structural regeneration of amputated appendages by blastema-mediated, epimorphic regeneration is a process whose mechanisms are beginning to be employed for inducing regeneration. While epimorphic regeneration is classically studi
Externí odkaz:
https://doaj.org/article/70345e430d4741d68396046541651079
Autor:
Ling Yu, Lindsay A. Dawson, Mingquan Yan, Katherine Zimmel, Yu-Lieh Lin, Connor P. Dolan, Manjong Han, Ken Muneoka
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Mammalian joints have poor regenerative capacity following amputation. Here, the authors show that in mice, stimulation of the amputation wound with BMP2 and BMP9 stimulates regeneration of a synovial joint that includes bone, cartilage and a synovia
Externí odkaz:
https://doaj.org/article/49ab87b3687b4f1eb6f372b52b35bc94
Autor:
Connor P. Dolan, Felisha Imholt, Mingquan Yan, Tae-Jung Yang, Joshua Gregory, Osama Qureshi, Katherine Zimmel, Kirby M. Sherman, Hannah M. Smith, Alyssa Falck, Eric Leininger, Ling Yu, Regina Brunauer, Larry J. Suva, Dana Gaddy, Lindsay A. Dawson, Ken Muneoka
Publikováno v:
Dev Biol
It is long-established that innervation-dependent production of neurotrophic factors is required for blastema formation and epimorphic regeneration of appendages in fish and amphibians. The regenerating mouse digit tip and the human fingertip are mam
Autor:
Ling Yu, Yu-Lieh Lin, Mingquan Yan, Tao Li, Emily Y. Wu, Katherine Zimmel, Osama Qureshi, Alyssa Falck, Kirby M. Sherman, Shannon S. Huggins, Daniel Osorio Hurtado, Larry J. Suva, Dana Gaddy, James Cai, Regina Brunauer, Lindsay A. Dawson, Ken Muneoka
Publikováno v:
Development. 149
Amputation injuries in mammals are typically non-regenerative; however, joint regeneration is stimulated by BMP9 treatment, indicating the presence of latent articular chondrocyte progenitor cells. BMP9 induces a battery of chondrogenic genes in vivo