Genetic association study of NLRP1, CARD, and CASP1 inflammasome genes with chronic Chagas cardiomyopathy among Trypanosoma cruzi seropositive patients in Bolivia.

Autor: Steven J Clipman, Josephine Henderson-Frost, Katherine Y Fu, Caryn Bern, Jorge Flores, Robert H Gilman

Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0192378 (2018)

About 20-30% of people infected with Chagas disease present with chronic Chagas cardiomyopathy (CCC), the most serious and frequent manifestation of the disease, while others remain asymptomatic and often do not experience Chagas-specific mortality.

Externí odkaz: https://doaj.org/article/c4873be713c741c794ed8c8fe6c5afc7

Association of caspase-1 polymorphisms with Chagas cardiomyopathy among individuals in Santa Cruz, Bolivia

Autor: Steven J. Clipman, Rony Colanzi, Alex Almuedo, Caryn Bern, Jo Henderson-Frost, Rachel Marcus, Katherine Y. Fu, Robert H. Gilman, Roxana Zamudio, Hannah E. Steinberg, Gustavo Duran, Thomas Crawford, Jorge Flores, Daniel Alyesh

Publikováno v: Revista da Sociedade Brasileira de Medicina Tropical v.50 n.4 2017
Revista da Sociedade Brasileira de Medicina Tropical
Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
Revista da Sociedade Brasileira de Medicina Tropical, Vol 50, Iss 4, Pp 516-523
Revista da Sociedade Brasileira de Medicina Tropical, Volume: 50, Issue: 4, Pages: 516-523, Published: AUG 2017
Rev Soc Bras Med Trop

INTRODUCTION: Trypanosoma cruzi (Tc) infection is usually acquired in childhood in endemic areas, leading to Chagas disease, which progresses to Chagas cardiomyopathy in 20-30% of infected individuals over decades. The pathogenesis of Chagas cardiomy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b274dfbb4410ba68135d99a5473ae75
https://doi.org/10.1590/0037-8682-0015-2017

Genetic association study of NLRP1, CARD, and CASP1 inflammasome genes with chronic Chagas cardiomyopathy among Trypanosoma cruzi seropositive patients in Bolivia

Autor: Robert H. Gilman, Katherine Y. Fu, Josephine Henderson-Frost, Caryn Bern, Steven J. Clipman, Jorge Flores

Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0192378 (2018)
PLoS ONE

About 20–30% of people infected with Chagas disease present with chronic Chagas cardiomyopathy (CCC), the most serious and frequent manifestation of the disease, while others remain asymptomatic and often do not experience Chagas-specific mortality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dc82cd61cad525b5dd474d06ea71bd
https://doi.org/10.1371/journal.pone.0192378

Quantitative Proteomics Reveal ATM Kinase-dependent Exchange in DNA Damage Response Complexes

Autor: Christopher J. Bakkenist, Rohith Srivas, Banu Dost, Trey Ideker, Nuno Bandeira, Bennett Van Houten, Serah Choi, Thomas P. Conrads, Gregory A. Gibson, Brian L. Hood, Katherine Y. Fu, Simon C. Watkins

ATM is a protein kinase that initiates a well-characterized signaling cascade in cells exposed to ionizing radiation (IR). However, the role for ATM in coordinating critical protein interactions and subsequent exchanges within DNA damage response (DD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b0ec713fdd22c8bd37e74721558809
https://europepmc.org/articles/PMC3495236/

Steroid Prophylaxis Prevents Acute Pain Flare or Swelling Sensation Following Cervical Spine Stereotactic Radiosurgery

Autor: Mubina Quader, Katherine Y. Fu, C.H. Kim, J.C. Flickinger, Peter C. Gerszten

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 84:S833

field data from the treatment planning system in DICOM format. Since most collisions with the patient are between the gantry head and the patient’s arms, and the arms are generally not fully included in the CT image, an algorithm to extrapolate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09e4ce2b25f8f585b46bd49d4ad00194
https://doi.org/10.1016/j.ijrobp.2012.07.2230