Výsledky vyhledávání - "Katherine W Ferrara"

Akademický článek

Magnetic resonance imaging assessment of effective ablated volume following high intensity focused ultrasound.

Autor: Brett Z Fite, Andrew Wong, Yu Liu, Lisa M Mahakian, Sarah M Tam, Olulanu Aina, Neil E Hubbard, Alexander Borowsky, Robert D Cardiff, Erik Dumont, Katherine W Ferrara

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120037 (2015)

Under magnetic resonance (MR) guidance, high intensity focused ultrasound (HIFU) is capable of precise and accurate delivery of thermal dose to tissues. Given the excellent soft tissue imaging capabilities of MRI, but the lack of data on the correlat

Externí odkaz: https://doaj.org/article/6c5a3563814f43eab5de5380115e6145

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Akademický článek

Concurrent Visualization of Acoustic Radiation Force Displacement and Shear Wave Propagation with 7T MRI.

Autor: Yu Liu, Brett Z Fite, Lisa M Mahakian, Sarah M Johnson, Benoit Larrat, Erik Dumont, Katherine W Ferrara

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0139667 (2015)

Manual palpation is a common and very informative diagnostic tool based on estimation of changes in the stiffness of tissues that result from pathology. In the case of a small lesion or a lesion that is located deep within the body, it is difficult f

Externí odkaz: https://doaj.org/article/737551f5628741768c935b9c74a6af5d

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Akademický článek

Spatial and Temporal Control of Hyperthermia Using Real Time Ultrasonic Thermal Strain Imaging with Motion Compensation, Phantom Study.

Autor: Josquin Foiret, Katherine W Ferrara

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0134938 (2015)

Mild hyperthermia has been successfully employed to induce reversible physiological changes that can directly treat cancer and enhance local drug delivery. In this approach, temperature monitoring is essential to avoid undesirable biological effects

Externí odkaz: https://doaj.org/article/8fd2ccdaa2a94a88a333547aee3d9ed9

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Akademický článek

Magnetic resonance thermometry at 7T for real-time monitoring and correction of ultrasound induced mild hyperthermia.

Autor: Brett Z Fite, Yu Liu, Dustin E Kruse, Charles F Caskey, Jeffrey H Walton, Chun-Yen Lai, Lisa M Mahakian, Benoit Larrat, Erik Dumont, Katherine W Ferrara

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35509 (2012)

While Magnetic Resonance Thermometry (MRT) has been extensively utilized for non-invasive temperature measurement, there is limited data on the use of high field (≥7T) scanners for this purpose. MR-guided Focused Ultrasound (MRgFUS) is a promising

Externí odkaz: https://doaj.org/article/6f3f574c66fa4a7f93e004b3560127d7

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Akademický článek

An open environment CT-US fusion for tissue segmentation during interventional guidance.

Autor: Charles F Caskey, Mario Hlawitschka, Shengping Qin, Lisa M Mahakian, Robert D Cardiff, John M Boone, Katherine W Ferrara

Publikováno v: PLoS ONE, Vol 6, Iss 11, p e27372 (2011)

Therapeutic ultrasound (US) can be noninvasively focused to activate drugs, ablate tumors and deliver drugs beyond the blood brain barrier. However, well-controlled guidance of US therapy requires fusion with a navigational modality, such as magnetic

Externí odkaz: https://doaj.org/article/fae098257d3043f2b321df425eba933b

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Akademický článek

Sonogenetic control of multiplexed genome regulation and base editing

Autor: Pei Liu, Josquin Foiret, Yinglin Situ, Nisi Zhang, Aris J. Kare, Bo Wu, Marina N. Raie, Katherine W. Ferrara, Lei S. Qi

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)

Abstract Manipulating gene expression in the host genome with high precision is crucial for controlling cellular function and behavior. Here, we present a precise, non-invasive, and tunable strategy for controlling the expression of multiple endogeno

Externí odkaz: https://doaj.org/article/7e18307bf8a7414cb4a83d6cc46380da

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Akademický článek

Protocol for in vitro sonoporation validation using non-targeted microbubbles for human studies of ultrasound-mediated gene delivery

Autor: Nisi Zhang, Yutong Guo, Josquin Foiret, Spencer K. Tumbale, Ramasamy Paulmurugan, Katherine W. Ferrara

Publikováno v: STAR Protocols, Vol 4, Iss 4, Pp 102723- (2023)

Summary: Microbubbles are currently approved for diagnostic ultrasound imaging and are under evaluation in therapeutic protocols. Here, we present a protocol for in vitro sonoporation validation using non-targeted microbubbles for gene delivery. We d

Externí odkaz: https://doaj.org/article/51814e6ed07247008dae53221f31a339

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