Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Katherine W Cook"'
Autor:
Ian Pike, Victoria A Brentville, Peter Symonds, Katherine W Cook, Lindy G Durrant, Sabaria Shah, Samantha J Paston, Juliane Weißer, Anne Skinner, Abdullah Al Omari
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Post-translational modification of proteins has the potential to alter the ability of T cells to recognize major histocompatibility complex (MHC) class -I and class-II restricted antigens, thereby resulting in altered immune responses. One
Externí odkaz:
https://doaj.org/article/342d5a87314b4e2e86c9b1772995e11a
Autor:
Victoria A Brentville, Rachael L Metheringham, Ian Daniels, Peter Symonds, Katherine W Cook, Mohamed Gijon, Lindy G Durrant, Ruhul H Choudhury, Samantha J Paston
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/2b8c7865e85b450a842ca77fb4634bb2
Autor:
Wei Xue, Victoria A Brentville, Rachael L Metheringham, Ian Daniels, Suha Atabani, Peter Symonds, Katherine W Cook, Poonam Vaghela, Mohamed Gijon, Lindy G Durrant, David Boocock, Clare Coveney, Amanda K Miles, Sabaria Shah, Ruhul H Choudhury, Daisy Weston
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Homocitrullination is the post-translational modification of lysine that is recognized by T cells.Methods This study identified homocitrullinated peptides from aldolase, enolase, cytokeratin and binding immunoglobulin protein and used huma
Externí odkaz:
https://doaj.org/article/8304c7bef9614211b835d19438adf38c
Autor:
Victoria A Brentville, Rachael L Metheringham, Ian Daniels, Suha Atabani, Peter Symonds, Katherine W Cook, Mireille Vankemmelbeke, Ruhul Choudhury, Poonam Vaghela, Mohamed Gijon, Ghislaine Meiners, Willem-Jan Krebber, Cornelis J M Melief, Lindy G Durrant
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Stress-induced post-translational modifications occur during autophagy and can result in generation of new epitopes and immune recognition. One such modification is the conversion of arginine to citrulline by peptidylarginine deiminase enz
Externí odkaz:
https://doaj.org/article/646c4a138fd4417ea278c37406bd14b0
Autor:
Victoria A Brentville, Peter Symonds, Katherine W Cook, Ian Daniels, Tracy Pitt, Mohamed Gijon, Poonam Vaghela, Wei Xue, Sabaria Shah, Rachael L Metheringham, Lindy G Durrant
Publikováno v:
OncoImmunology, Vol 8, Iss 5 (2019)
Post-translational modifications are induced in stressed cells which cause them to be recognised by the system. One such modification is citrullination where the positive charged arginine is modified to a neutral citrulline. We demonstrate most healt
Externí odkaz:
https://doaj.org/article/50f7794fe18c404f878327e37bf15e3e
Autor:
Ruhul H. Choudhury, Ian Daniels, Poonam Vaghela, Suha Atabani, Thomas Kirk, Peter Symonds, Katherine W. Cook, Abdullah Al‐Omari, Daisy Weston, Sabaria Shah, David Hutchinson, Samantha J. Paston, Rachael L. Metheringham, Victoria A. Brentville, Lindy G. Durrant
Publikováno v:
Immunology.
Autor:
Sabaria Shah, Abdullah Al-Omari, Katherine W Cook, Samantha J Paston, Lindy G Durrant, Victoria A Brentville
Publikováno v:
Discovery Immunology. 2
Summary Complex cellular interactions between the immune system and cancer can impact tumour development, growth, and progression. T cells play a key role in these interactions; however, the challenge for T cells is to recognize tumour antigens whils
Autor:
Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
BackgroundThe enzymatic conversion of arginine to citrulline is involved in gene and protein regulation and in alerting the immune system to stressed cells, including tumor cells. Nucleophosmin (NPM) is a nuclear protein that plays key roles in cellu
Autor:
Peter Symonds, Ana Marcu, Katherine W. Cook, Rachael L. Metheringham, Lindy G. Durrant, Victoria A. Brentville
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
BackgroundSomatic mutations or post-translational modifications of proteins result in changes that enable immune recognition. One such post-translational modification is citrullination, the conversion of arginine residues to citrulline. Citrullinated
Autor:
Victoria A. Brentville, Suha Atabani, Mohamed Gijon, Ian Daniels, Clare Coveney, Lindy G. Durrant, Peter Symonds, David J. Boocock, Poonam Vaghela, Amanda K. Miles, Katherine W. Cook, Sabaria Shah, Rachael L. Metheringham, Ruhul Choudhury, Wei Xue, Daisy Weston
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Journal for ImmunoTherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
BackgroundHomocitrullination is the post-translational modification of lysine that is recognized by T cells.MethodsThis study identified homocitrullinated peptides from aldolase, enolase, cytokeratin and binding immunoglobulin protein and used human