Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Katherine V Houser"'
Autor:
Cristina Carter, Katherine V Houser, Galina V Yamshchikov, Abbie R Bellamy, Jeanine May, Mary E Enama, Uzma Sarwar, Brenda Larkin, Robert T Bailer, Richard Koup, Grace L Chen, Shital M Patel, Patricia Winokur, Robert Belshe, Cornelia L Dekker, Barney S Graham, Julie E Ledgerwood, VRC 703 study team
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222178 (2019)
BackgroundSeasonal influenza results in significant morbidity and mortality worldwide, but the currently licensed inactivated vaccines generally have low vaccine efficacies and could be improved. In this phase 1 clinical trial, we compared seasonal i
Externí odkaz:
https://doaj.org/article/773f84c8b2754fefbbb0e4d8279bce2c
Autor:
Joseph P. Casazza, Amelia R. Hofstetter, Pamela J. M. Costner, LaSonji A. Holman, Cynthia S. Hendel, Alicia T. Widge, Richard L. Wu, William R. Whalen, Jennifer Cunningham, Anita Arthur, Xiaolin Wang, Abidemi Ola, Jamie Saunders, Floreliz Mendoza, Laura Novik, Maria C. Burgos Florez, Ana M. Ortega-Villa, Preeti J. Apte, Larisa Strom, Lu Wang, Marjaan Imam, Manjula Basappa, Mursal Naisan, Mike Castro, Jessica F. Trost, Sandeep R. Narpala, Hillary A. Vanderven, Galina V. Yamshchikov, Nina M. Berkowitz, Ingelise J. Gordon, Sarah H. Plummer, Diane L. Wycuff, Sandra Vazquez, Rebecca A. Gillespie, Adrian Creanga, William C. Adams, Kevin Carlton, Jason G. Gall, Adrian B. McDermott, Leonid A. Serebryannyy, Katherine V. Houser, Richard A. Koup, Barney S. Graham, Julie E. Ledgerwood, John R. Mascola, Theodore C. Pierson, Sarah F. Andrews, Masaru Kanekiyo, Lesia K. Dropulic, The VRC 323 study team
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract The relative conservation of the influenza hemagglutinin (HA) stem compared to that of the immunodominant HA head makes the HA stem an attractive target for broadly protective influenza vaccines. Here we report the first-in-human, dose-escal
Externí odkaz:
https://doaj.org/article/96bea20f4a6e46d8a78a3f7c6943f262
Autor:
Martin R Gaudinski, Emily E Coates, Katherine V Houser, Grace L Chen, Galina Yamshchikov, Jamie G Saunders, LaSonji A Holman, Ingelise Gordon, Sarah Plummer, Cynthia S Hendel, Michelle Conan-Cibotti, Margarita Gomez Lorenzo, Sandra Sitar, Kevin Carlton, Carolyn Laurencot, Robert T Bailer, Sandeep Narpala, Adrian B McDermott, Aryan M Namboodiri, Janardan P Pandey, Richard M Schwartz, Zonghui Hu, Richard A Koup, Edmund Capparelli, Barney S Graham, John R Mascola, Julie E Ledgerwood, VRC 606 Study Team
Publikováno v:
PLoS Medicine, Vol 15, Iss 1, p e1002493 (2018)
BACKGROUND:VRC01 is a human broadly neutralizing monoclonal antibody (bnMAb) against the CD4-binding site of the HIV-1 envelope glycoprotein (Env) that is currently being evaluated in a Phase IIb adult HIV-1 prevention efficacy trial. VRC01LS is a mo
Externí odkaz:
https://doaj.org/article/7064e5c4178543e0a29e54c0e8e750e5
Autor:
Katherine V Houser, Galina V Yamshchikov, Abbie R Bellamy, Jeanine May, Mary E Enama, Uzma Sarwar, Brenda Larkin, Robert T Bailer, Richard Koup, Myeisha Paskel, Kanta Subbarao, Edwin Anderson, David I Bernstein, Buddy Creech, Harry Keyserling, Paul Spearman, Peter F Wright, Barney S Graham, Julie E Ledgerwood, VRC 702 study team
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206837 (2018)
BACKGROUND:Children are susceptible to severe influenza infections and facilitate community transmission. One potential strategy to improve vaccine immunogenicity in children against seasonal influenza involves a trivalent hemagglutinin DNA prime-tri
Externí odkaz:
https://doaj.org/article/67936566033b4b438ee217c20baa6439
Autor:
Katherine V Houser, Andrew J Broadbent, Lisa Gretebeck, Leatrice Vogel, Elaine W Lamirande, Troy Sutton, Kevin W Bock, Mahnaz Minai, Marlene Orandle, Ian N Moore, Kanta Subbarao
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006565 (2017)
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic betacoronavirus that was first detected in humans in 2012 as a cause of severe acute respiratory disease. As of July 28, 2017, there have been 2,040 confirmed cases with 712 re
Externí odkaz:
https://doaj.org/article/5499366309094999abbabe0c5e7acc35
Autor:
Myra Happe, Amelia R. Hofstetter, Jing Wang, Galina V. Yamshchikov, LaSonji A. Holman, Laura Novik, Larisa Strom, Francis Kiweewa, Salim Wakabi, Monica Millard, Colleen F. Kelley, Sarah Kabbani, Srilatha Edupuganti, Allison Beck, Florence Kaltovich, Tamar Murray, Susanna Tsukerman, Derick Carr, Carl Ashman, Daphne A. Stanley, Aurélie Ploquin, Robert T. Bailer, Richard Schwartz, Fatim Cham, Allan Tindikahwa, Zonghui Hu, Ingelise J. Gordon, Nadine Rouphael, Katherine V. Houser, Emily E. Coates, Barney S. Graham, Richard A. Koup, John R. Mascola, Nancy J. Sullivan, Merlin L. Robb, Julie A. Ake, Kirsten E. Lyke, Mark J. Mulligan, Julie E. Ledgerwood, Hannah Kibuuka, the VRC 208 and RV 422 study team
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Ebola virus disease (EVD) is a filoviral infection caused by virus species of the Ebolavirus genus including Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV). We investigated the safety and immunogenicity of a heterologous prime-boost reg
Externí odkaz:
https://doaj.org/article/a738fdd17f884be498b68c55cc2e29cd
Autor:
Graeme E Price, Mark R Soboleski, Chia-Yun Lo, Julia A Misplon, Mary R Quirion, Katherine V Houser, Melissa B Pearce, Claudia Pappas, Terrence M Tumpey, Suzanne L Epstein
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13162 (2010)
The sudden emergence of novel influenza viruses is a global public health concern. Conventional influenza vaccines targeting the highly variable surface glycoproteins hemagglutinin and neuraminidase must antigenically match the emerging strain to be
Externí odkaz:
https://doaj.org/article/3c55951b4590409c84b9927738a0bd55
Autor:
Yuhe R. Yang, Julianna Han, Hailee R. Perrett, Sara T. Richey, Alesandra J. Rodriguez, Abigail M. Jackson, Rebecca A. Gillespie, Sarah O’Connell, Julie E. Raab, Lauren Y. Cominsky, Ankita Chopde, Masaru Kanekiyo, Katherine V. Houser, Grace L. Chen, Adrian B. McDermott, Sarah F. Andrews, Andrew B. Ward
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114171- (2024)
Summary: Influenza A virus subtype H2N2, which caused the 1957 influenza pandemic, remains a global threat. A recent phase 1 clinical trial investigating a ferritin nanoparticle vaccine displaying H2 hemagglutinin (HA) in H2-naive and H2-exposed adul
Externí odkaz:
https://doaj.org/article/a0c95ce71b2948fb906573474156e723
Autor:
Melinda J Hamer, Katherine V Houser, Amelia R Hofstetter, Ana M Ortega-Villa, Christine Lee, Anne Preston, Brooke Augustine, Charla Andrews, Galina V Yamshchikov, Somia Hickman, Steven Schech, Jack N Hutter, Paul T Scott, Paige E Waterman, Mihret F Amare, Victoria Kioko, Casey Storme, Kayvon Modjarrad, Melanie D McCauley, Merlin L Robb, Martin R Gaudinski, Ingelise J Gordon, LaSonji A Holman, Alicia T Widge, Larisa Strom, Myra Happe, Josephine H Cox, Sandra Vazquez, Daphne A Stanley, Tamar Murray, Caitlyn N M Dulan, Ruth Hunegnaw, Sandeep R Narpala, Phillip A Swanson, Manjula Basappa, Jagada Thillainathan, Marcelino Padilla, Britta Flach, Sarah O’Connell, Olga Trofymenko, Patricia Morgan, Emily E Coates, Jason G Gall, Adrian B McDermott, Richard A Koup, John R Mascola, Aurélie Ploquin, Nancy J Sullivan, Julie A Ake, Julie E Ledgerwood, Rebecca Lampley, Brenda Larkin, Pamela Costner, Hope Wilson, Mike Read
Publikováno v:
The Lancet. 401:294-302
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6abe893c24f039ecd7b168efa612fd21
https://doi.org/10.1016/s0140-6736(22)02400-x
https://doi.org/10.1016/s0140-6736(22)02400-x
Autor:
Sarah F. Andrews, Lauren Y. Cominsky, Geoffrey D. Shimberg, Rebecca A. Gillespie, Jason Gorman, Julie E. Raab, Joshua Brand, Adrian Creanga, Suprabhath R. Gajjala, Sandeep Narpala, Crystal S. F. Cheung, Darcy R. Harris, Tongqing Zhou, Ingelise Gordon, LaSonji Holman, Floreliz Mendoza, Katherine V. Houser, Grace L. Chen, John R. Mascola, Barney S. Graham, Peter D. Kwong, Alicia Widge, Lesia K. Dropulic, Julie E. Ledgerwood, Masaru Kanekiyo, Adrian B. McDermott
Publikováno v:
Science Translational Medicine. 15
Current yearly seasonal influenza vaccines primarily induce an antibody response directed against the immunodominant but continually diversifying hemagglutinin (HA) head region. These antibody responses provide protection against the vaccinating stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8327a089c0f6592ca35ba268306ede9d
https://doi.org/10.1126/scitranslmed.ade4976
https://doi.org/10.1126/scitranslmed.ade4976