Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Katherine Stepan"'
Publikováno v:
Carcinogenesis. 4:1327-1331
Studies were conducted to evaluate the possibility of a bile reflux mechanism in the etiology of induced pancreatic cancer. N-Nitrosobis(2-oxopropyl)amine (BOP) was administered to Syrian hamsters after partial pancreatico-colostomy. Either the gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba80a859231c0e38c11f54f330bea06
https://doi.org/10.1093/carcin/4.10.1327
https://doi.org/10.1093/carcin/4.10.1327
Publikováno v:
JNCI: Journal of the National Cancer Institute. 63:797-811
Hamsters of three types designated as inbred cream (Epp/e/e), linebred white (EPP/cdcd/RB/A), and linebred albino (EPP/cdcde/e) were thoroughly examined histopathologically for spontaneous diseases. All hamsters were maintained simultaneously for lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::077a011c54a9e13507c4a95f184209e1
https://doi.org/10.1093/jnci/63.3.797
https://doi.org/10.1093/jnci/63.3.797
Publikováno v:
Cancer Letters. 10:163-167
Weekly topical application of equitoxic doses of N-nitrosobis(2-oxopropyl)amine (BOP) or N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine (HPOP) to lip and/or vagina of female Syrian hamsters led to the development of papillomas and carcinomas of the lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0469cfafaa06ef9cb333d42dc4e5ed1c
https://doi.org/10.1016/0304-3835(80)90040-3
https://doi.org/10.1016/0304-3835(80)90040-3
Publikováno v:
JNCI: Journal of the National Cancer Institute. 72:191-194
Pilocarpine hydrochloride (PH) was administered as a single sc injection (15 mg/kg body wt) to outbred Syrian golden hamsters either prior to, simultaneously with, or after a single 20-mg/kg body weight dose of the pancreatic carcinogen N-nitrosobis(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb19e6328b879eb286266bbd5ede7ab
https://doi.org/10.1093/jnci/72.1.191
https://doi.org/10.1093/jnci/72.1.191
Autor:
Lawrence Wallcave, Donald Nagel, Katherine Stepan, Ralph Gingell, Richard G. Runge, Shahrokh Salmasi, Parviz M. Pour
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Weekly sc injections of equitoxic doses of N-nitrosobis(2-hydroxypropyl)amine (BHP) and N-nitrosobis(2-oxopropyl)amine (BOP) to Wister-derived MRC rats induced tumors. The incidence, latency, multiplicity, morphologic type, and distribution of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3904fb56216167f258719fc37c0efbb1
https://doi.org/10.1093/jnci/63.1.181
https://doi.org/10.1093/jnci/63.1.181
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Ethanol (E) was given to outbred Syrian golden hamsters in drinking water at a 5% (wt/vol) concentration for life beginning either before or after a single dose of N-nitrosobis(2-oxopropyl)amine (BOP). No effects on tumor induction were seen in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776647d447588352443c78a1607a542d
https://doi.org/10.1093/jnci/71.5.1085
https://doi.org/10.1093/jnci/71.5.1085
Publikováno v:
JNCI: Journal of the National Cancer Institute.
The effect of acute and recurrent pancreatitis was investigated in pancreatic cancer induction by N-nitrosobis(2-oxopropyl)amine (BOP) in Syrian golden hamsters. For the correlation of the cellular alteration with carcinogenesis, BOP (20 mg/kg body w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0121502650504c7ac098933bb58c752
https://doi.org/10.1093/jnci/71.3.607
https://doi.org/10.1093/jnci/71.3.607
Autor:
Parviz M. Pour, Katherine Stepan
Publikováno v:
Carcinogenesis. 9(8)
In a previous study in rats we have shown that castration prior to weekly administration of N-nitrosobis(2-oxopropyl)amine (BOP) prevents induction of nasal and paranasal cavity (NPNC) tumors, indicating androgen dependency of these neoplasms. To inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72716cdc2015726d3f0d18552cf36d97
https://pubmed.ncbi.nlm.nih.gov/3402038
https://pubmed.ncbi.nlm.nih.gov/3402038
Autor:
Parviz M. Pour, Katherine Stepan
Publikováno v:
JNCI: Journal of the National Cancer Institute.
The effect of exogenous insulin, which has been known to suppress beta-cell function of islets, was investigated on pancreatic carcinogenesis induced by N-nitrosobis(2-oxopropyl) amine [(BOP) CAS: 60599-38-4; 2,2'-dioxo-N-nitrosodipropylamine]. Three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::810923d3927e04a47efcbaa0a7441447
https://doi.org/10.1093/jnci/72.5.1205
https://doi.org/10.1093/jnci/72.5.1205
Autor:
Katherine Stepan, Parviz M. Pour
Publikováno v:
Cancer letters. 27(3)
Weekly application of N-nitrosobis (2-hydroxypropyl) amine (BHP) at a dose of 50 mg/application to the skin of the neck and flank organ of male Syrian golden hamsters induced no local lesions. However, nearly all treated animals developed internal tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e487a52f7d7145387a8875692c3c136d
https://pubmed.ncbi.nlm.nih.gov/4016724
https://pubmed.ncbi.nlm.nih.gov/4016724