Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Katherine Schiermeyer"'
Autor:
Wei Yue, Hanh T. Tran, Ji-ping Wang, Katherine Schiermeyer, John J. Gildea, Peng Xu, Robin A. Felder
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 15 (2021)
Purpose: Clinical studies have shown that breast cancer risk is increased in hypertensive women. The underlying molecular mechanism remains undetermined. The current study tests our hypothesis that G protein coupled receptor kinase 4 (GRK4) is a mole
Externí odkaz:
https://doaj.org/article/51082e0ac8b747cf8580ce08e95f139d
Autor:
Robin A. Felder, Pedro A. Jose, Peng Xu, Wei Yue, John J Gildea, Katherine Schiermeyer, Robert M. Carey
Publikováno v:
Hypertension. 76
Inverse salt sensitivity is the paradoxical increase in blood pressure of individuals to a low sodium diet. rs6276, a single nucleotide polymorphism found in the 3’ untranslated region of the D2R gene (DRD2), which is associated with decreased expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb990fa8935c901d2172888b9392206b
https://doi.org/10.1161/hyp.76.suppl_1.12
https://doi.org/10.1161/hyp.76.suppl_1.12
Autor:
Peng Xu, Katherine Schiermeyer, Jiping Wang, Stephen Marshall, Wei Yue, John J Gildea, Robin A. Felder
Publikováno v:
Hypertension. 76
The renal dopaminergic D 1 receptor (D 1 R) regulates sodium excretion which is terminated by phosphorylation by G protein-coupled receptor kinases 4 (GRK4). GRK4 gene variants are associated with increased GRK4 activity and reduced sodium excretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b679677d5fdabacc13593e21ac63056a
https://doi.org/10.1161/hyp.76.suppl_1.p005
https://doi.org/10.1161/hyp.76.suppl_1.p005
Autor:
Peng Xu, John J Gildea, Robin A. Felder, Pedro A. Jose, Robert M. Carey, Wei Yue, Katherine Schiermeyer, Michael G Daley
Publikováno v:
Hypertension. 76
Increased morbidity and mortality occurs in some individuals consuming low sodium diets. We demonstrated that single nucleotide polymorphisms (SNPs) in the dopamine type 2 receptor (D2R) as well as lower expression of cellular and plasma membrane D2R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ffd3b12dd0d7efa12ed84059951de8c
https://doi.org/10.1161/hyp.76.suppl_1.p009
https://doi.org/10.1161/hyp.76.suppl_1.p009
Autor:
Peng Xu, John J Gildea, Pedro A. Jose, Robert M. Carey, Wei Yue, Michael G Daley, Katherine Schiermeyer, Robin A. Felder
Publikováno v:
Hypertension. 76
Cardiovascular studies show increased morbidity and mortality in individuals consuming low sodium diets as well as high salt diets. The incidence of salt sensitivity of blood pressure (SS) in normotensives is approximately 18%, causing similar mortal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83601917243d892fa6610bbbaac6331c
https://doi.org/10.1161/hyp.76.suppl_1.p010
https://doi.org/10.1161/hyp.76.suppl_1.p010
Autor:
Stephen Marshall, Katherine Schiermeyer, John J Gildea, Peng Xu, Mahabuba Akhter, Wei Yue, Robin A. Felder, Robert M. Carey
Publikováno v:
Hypertension. 76
Ambulatory blood pressure monitoring is more useful for the diagnosis of various forms of hypertension including white coat and morning surge as well as other conditions that are associated with increased morbidity and mortality such as sleep apnea.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663bb62bc0f21df4d0130f435b6e4c3d
https://doi.org/10.1161/hyp.76.suppl_1.p205
https://doi.org/10.1161/hyp.76.suppl_1.p205
Autor:
Stephen Marshall, John J Gildea, Kwabena Sarpong, Katherine Schiermeyer, Peng Xu, Wei Yue, Robin A. Felder
Publikováno v:
Hypertension. 76
Renal proximal tubule (RPT) dopamine D 1 -like receptors (D 1 R) and angiotensin II type-2 receptor (AT 2 R) inhibit sodium reabsorption and counter regulate the renin angiotensin systems AT 1 R which stimulates sodium reabsorption. Salt sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd7a0e94617a74e0c4ffced595a81b67
https://doi.org/10.1161/hyp.76.suppl_1.p018
https://doi.org/10.1161/hyp.76.suppl_1.p018
Autor:
Peng Xu, Robin A. Felder, Wei Yue, John J Gildea, Pedro A. Jose, Katherine Schiermeyer, Robert M. Carey
Publikováno v:
Hypertension. 76
The effect of D2R expression on the natriuretic AT2R plasma membrane recruitment in high (190 mM NaCl) and normal (140 mM NaCl) salt conditions was measured in human renal proximal tubule cells (RPTC) obtained from urine provided by salt study diet v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6d6cb2f4b3e4cc19dfbccf044c2948a
https://doi.org/10.1161/hyp.76.suppl_1.p032
https://doi.org/10.1161/hyp.76.suppl_1.p032
Publikováno v:
Hypertension. 74
The dopamine type 1 (D 1 R) and angiotensin type 2 (AT 2 R) are both natriuretic receptors that regulate renal sodium homeostasis. Aberrant D 1 R and AT 2 R mechanisms are implicated in hypertension, salt-sensitive hypertension, and in normotensive s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f35f4ad589b71c93380229d7133148a
https://doi.org/10.1161/hyp.74.suppl_1.p2047
https://doi.org/10.1161/hyp.74.suppl_1.p2047
Autor:
John J Gildea, Katherine Schiermeyer, Robin A. Felder, Daria Ilatovskaya, Charleston V Sudarikova, Peng Xu, Wei Yue
Publikováno v:
Hypertension. 74
The amiloride-sensitive epithelial sodium channel (ENaC) localizes to the apical membrane of epithelial cells in distal nephron, playing an important role in regulating whole-body Na + homeostasis and blood pressure. We were the first to describe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5661c396feb1f4dfae6fe294d35bf045
https://doi.org/10.1161/hyp.74.suppl_1.p199
https://doi.org/10.1161/hyp.74.suppl_1.p199