Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Katherine S. Forsyth"'
Autor:
Asif A. Dar, Dale D. Kim, Scott M. Gordon, Kathleen Klinzing, Siera Rosen, Ipsita Guha, Nadia Porter, Yohaniz Ortega, Katherine S. Forsyth, Jennifer Roof, Hossein Fazelinia, Lynn A. Spruce, Laurence C. Eisenlohr, Edward M. Behrens, Paula M. Oliver
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract During infection, virus-specific CD8+ T cells undergo rapid bursts of proliferation and differentiate into effector cells that kill virus-infected cells and reduce viral load. This rapid clonal expansion can put T cells at significant risk f
Externí odkaz:
https://doaj.org/article/13ee6ca256cb4b35a160900e56452abc
Autor:
Katherine S Forsyth, Nathan H Roy, Elise Peauroi, Brian C DeHaven, Erik D Wold, Adam R Hersperger, Janis K Burkhardt, Laurence C Eisenlohr
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008685 (2020)
Smallpox and monkeypox pose severe threats to human health. Other orthopoxviruses are comparably virulent in their natural hosts, including ectromelia, the cause of mousepox. Disease severity is linked to an array of immunomodulatory proteins includi
Externí odkaz:
https://doaj.org/article/cbe58d5655a243ab9ea7b8e6f10f1425
Autor:
Brian C. DeHaven, Mark Mendonca, Katherine S. Forsyth, Alessandro Sette, Laurence C. Eisenlohr, Sinu Paul
Publikováno v:
The Journal of Immunology. 202:1340-1349
CD4+ T cells play critical roles in defending against poxviruses, both by potentiating cellular and humoral responses and by directly killing infected cells. Despite this central role, the basis for pox-specific CD4+ T cell activation, specifically t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::084061a4d99754ee06cd64e2e8fe7aed
https://doi.org/10.4049/jimmunol.1801099
https://doi.org/10.4049/jimmunol.1801099
Publikováno v:
Current Opinion in Physiology
Females have more robust immune responses than males, and viral infections are more severe for males. Hormones and genetic sex, namely the X chromosome, influence sex differences with immune responses. Here, we review recent findings underlying sexua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267ca46ae26fddde44823ab135e1f1df
https://pubmed.ncbi.nlm.nih.gov/33073073
https://pubmed.ncbi.nlm.nih.gov/33073073
Autor:
Brian C. De Haven, Erin S. Hand, Marie C. Pizzorno, Tiffany R. Frey, Katherine S. Forsyth, Maura M. Sheehan, Julia G. Pevarnik, Laurence C. Eisenlohr, Adam R. Hersperger
Publikováno v:
Virology. 518:335-348
All known orthopoxviruses, including ectromelia virus (ECTV), contain a gene in the E3L family. The protein product of this gene, E3, is a double-stranded RNA-binding protein. It can impact host range and is used by orthopoxviruses to combat cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8889d8ad38aa5afacb2327512c5b1a69
https://doi.org/10.1016/j.virol.2018.03.016
https://doi.org/10.1016/j.virol.2018.03.016
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1988
The study of antigen processing and presentation is critical to our understanding of the mechanisms that govern immune surveillance. A typical requirement of assays designed to examine antigen processing and presentation is the de novo biosynthesis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f13400093970399872f532887a70d8d1
https://pubmed.ncbi.nlm.nih.gov/31147943
https://pubmed.ncbi.nlm.nih.gov/31147943
Publikováno v:
Antigen Processing ISBN: 9781493994496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61504d24fd5249dec76f902f4e783458
https://doi.org/10.1007/978-1-4939-9450-2_16
https://doi.org/10.1007/978-1-4939-9450-2_16
Autor:
Elise Peauroi, Erik D. Wold, Janis K. Burkhardt, Katherine S. Forsyth, Nathan H. Roy, Laurence C. Eisenlohr, Adam R. Hersperger, Brian C. DeHaven
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008685 (2020)
PLoS Pathogens
PLoS Pathogens
Smallpox and monkeypox pose severe threats to human health. Other orthopoxviruses are comparably virulent in their natural hosts, including ectromelia, the cause of mousepox. Disease severity is linked to an array of immunomodulatory proteins includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce23ccad9caa0c48d9e4f590adf880f
https://doi.org/10.1371/journal.ppat.1008685
https://doi.org/10.1371/journal.ppat.1008685
Publikováno v:
The Journal of Immunology. 204:248.8-248.8
The success of poxviruses as pathogens depends upon their extensive antagonism of host immune responses by a large arsenal of immunomodulatory proteins. The C15 protein of ectromelia virus (ECTV, the agent of mousepox) is the largest of the ECTV immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f6dc3cc921664158e8b2df977a158a0
https://doi.org/10.4049/jimmunol.204.supp.248.8
https://doi.org/10.4049/jimmunol.204.supp.248.8
Autor:
Katherine S, Forsyth, Brian, DeHaven, Mark, Mendonca, Sinu, Paul, Alessandro, Sette, Laurence C, Eisenlohr
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(5)
CD4+ T cells play critical roles in defending against poxviruses, both by potentiating cellular and humoral responses and by directly killing infected cells. Despite this central role, the basis for pox-specific CD4+ T cell activation, specifically t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db66fd1896bfba764835230b8d9396ac
https://pubmed.ncbi.nlm.nih.gov/30700590
https://pubmed.ncbi.nlm.nih.gov/30700590