Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katherine S Bridge"'
Autor:
Daniel E Foxler, Katherine S Bridge, John G Foster, Paul Grevitt, Sean Curry, Kunal M Shah, Kathryn M Davidson, Ai Nagano, Emanuela Gadaleta, Hefin I Rhys, Paul T Kennedy, Miguel A Hermida, Ting‐Yu Chang, Peter E Shaw, Louise E Reynolds, Tristan R McKay, Hsei‐Wei Wang, Paulo S Ribeiro, Michael J Plevin, Dimitris Lagos, Nicholas R Lemoine, Prabhakar Rajan, Trevor A Graham, Claude Chelala, Kairbaan M Hodivala‐Dilke, Ian Spendlove, Tyson V Sharp
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 8, Pp 1-18 (2018)
Abstract The adaptive cellular response to low oxygen tensions is mediated by the hypoxia‐inducible factors (HIFs), a family of heterodimeric transcription factors composed of HIF‐α and HIF‐β subunits. Prolonged HIF expression is a key contri
Externí odkaz:
https://doaj.org/article/9b04680e29334b599d9575042b42aeeb
Autor:
Kathryn Davidson, Paul Grevitt, Maria F. Contreras-Gerenas, Katherine S. Bridge, Miguel Hermida, Kunal M. Shah, Faraz K. Mardakheh, Mark Stubbs, Rosemary Burke, Pedro Casado, Pedro R. Cutillas, Sarah A. Martin, Tyson V. Sharp
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Abstract An early event in lung oncogenesis is loss of the tumour suppressor gene LIMD1 (LIM domains containing 1); this encodes a scaffold protein, which suppresses tumorigenesis via a number of different mechanisms. Approximately 45% of non-small c
Externí odkaz:
https://doaj.org/article/006a5cc989ef440e83fa93a4ded65708
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The haematopoietic system is a classical stem cell hierarchy that maintains all the blood cells in the body. Haematopoietic stem cells (HSCs) are rare, highly potent cells that reside at the apex of this hierarchy and are historically some of the mos
Externí odkaz:
https://doaj.org/article/81f41930c2d348d8afec038a07043cb3
Autor:
Katherine S. Bridge, Kunal M. Shah, Yigen Li, Daniel E. Foxler, Sybil C.K. Wong, Duncan C. Miller, Kathryn M. Davidson, John G. Foster, Ruth Rose, Michael R. Hodgkinson, Paulo S. Ribeiro, A. Aziz Aboobaker, Kenta Yashiro, Xiaozhong Wang, Paul R. Graves, Michael J. Plevin, Dimitris Lagos, Tyson V. Sharp
Publikováno v:
Cell Reports, Vol 20, Iss 1, Pp 173-187 (2017)
As core components of the microRNA-induced silencing complex (miRISC), Argonaute (AGO) proteins interact with TNRC6 proteins, recruiting other effectors of translational repression/mRNA destabilization. Here, we show that LIMD1 coordinates the assemb
Externí odkaz:
https://doaj.org/article/dd86764956e7461fbbd192078a7216b7
Autor:
Kyomi J Igarashi, Iwo Kucinski, Yan Yi Chan, Tze-Kai Tan, Hwei Minn Khoo, David Kealy, Joydeep Bhadury, Ian Hsu, Pui Yan Ho, Kouta Niizuma, John W Hickey, Garry Nolan, Katherine S Bridge, Agnieszka Czechowicz, Berthold Gottgens, Hiromitsu Nakauchi, Adam C Wilkinson
Hematopoietic stem cells (HSCs) are a rare hematopoietic cell type that can entirely reconstitute the blood and immune systems following transplantation. Allogeneic HSC transplantation (HSCT) is used clinically as a curative therapy for a range of he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2992d2e57974f834d61918b9f9c0247f
https://ora.ox.ac.uk/objects/uuid:2a38be79-3dcb-4a27-a289-044ce34d3cb8
https://ora.ox.ac.uk/objects/uuid:2a38be79-3dcb-4a27-a289-044ce34d3cb8
Autor:
William Grey, Samantha Atkinson, Beatrice Rix, Pedro Casado, Linda Ariza-McNaughton, Cathy Hawley, Miriam L. Sopoena, Katherine S. Bridge, David Kent, Pedro R. Cutillas, Dominique Bonnet
No description supplied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e6eb3ce18304e2737646bc2a26b652
Autor:
Pedro R. Cutillas, Mark Stubbs, Kunal Shah, Kathryn M. Davidson, Sarah A. Martin, Tyson V. Sharp, Pedro Casado, Paul Grevitt, Rosemary Burke, Maria F Contreras-Gerenas, Katherine S. Bridge, Miguel Hermida, Faraz K. Mardakheh
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
An early event in lung oncogenesis is loss of the tumour suppressor gene LIMD1 (LIM domains containing 1); this encodes a scaffold protein, which suppresses tumorigenesis via a number of different mechanisms. Approximately 45% of non-small cell lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e943a5d75254e5848162c3024ff0866
https://eprints.whiterose.ac.uk/180653/1/s41419_021_04355_7.pdf
https://eprints.whiterose.ac.uk/180653/1/s41419_021_04355_7.pdf
Autor:
Miguel Hermida, Pedro Casado-Izquierdo, Kunal Shah, Paul Grevitt, F G Maria Contreras, Sarah A. Martin, Rosemary Burke, Tyson V. Sharp, Paul A. Clarke, Mark Stubbs, Pedro R. Cutillas, Faraz K. Mardakheh, Kathryn M. Davidson, Katherine S. Bridge
An early event in lung oncogenesis is loss of the tumour suppressor gene LIMD1 (LIM domains containing 1); this encodes a scaffold protein, which suppresses tumourigenesis via a number of different mechanisms. Approximately 45% of non-small cell lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfcf10e4b33db6e1f7d26267c1986b6b
https://doi.org/10.1101/2021.02.01.429178
https://doi.org/10.1101/2021.02.01.429178
Autor:
A. Aziz Aboobaker, Paul R. Graves, Kunal Shah, Duncan Miller, Dimitris Lagos, Xiaozhong Wang, Michael R. Hodgkinson, Kathryn M. Davidson, Katherine S. Bridge, Yigen Li, Tyson V. Sharp, Kenta Yashiro, Sybil C.K. Wong, Paulo S. Ribeiro, Michael J. Plevin, John G. Foster, Ruth Sarah Rose, Daniel E. Foxler
Publikováno v:
Cell Reports
Cell Reports, Vol 20, Iss 1, Pp 173-187 (2017)
Cell Reports, Vol 20, Iss 1, Pp 173-187 (2017)
Summary As core components of the microRNA-induced silencing complex (miRISC), Argonaute (AGO) proteins interact with TNRC6 proteins, recruiting other effectors of translational repression/mRNA destabilization. Here, we show that LIMD1 coordinates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46d797594c0d8570ff6839e422e42e8
http://europepmc.org/articles/PMC5507773
http://europepmc.org/articles/PMC5507773
Autor:
Weiye Zhao, Susanna F Rose, Ryan Blake, Anže Godicelj, Amy E Cullen, Jack Stenning, Lucy Beevors, Marcel Gehrung, Sanjeev Kumar, Kamal Kishore, Ashley Sawle, Matthew Eldridge, Federico M Giorgi, Katherine S Bridge, Florian Markowetz, Andrew N Holding
The Estrogen Receptor (ER) drives 75% of breast cancers. On activation, the ER recruits co-factors to form a transcriptionally active complex. These co-factors can modulate tumour growth, and understanding their roles can help to identify new therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b82fd4893e4ef1f142031e0b88b7192b
https://doi.org/10.1101/789610
https://doi.org/10.1101/789610