Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Katherine R. Thain"'
Autor:
Elaine Cadogan, Andrew Churg, Don D. Sin, Katherine R. Thain, Justine Maltby, S J Bolton, Philip Mallinder, Caroline Marshall, Joanne L. Wright, Matthew G. Soars, Steven Zhou
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 185:34-43
Inflammation and oxidative stress are linked to the deleterious effects of cigarette smoke in producing chronic obstructive pulmonary disease (COPD). Myeloperoxidase (MPO), a neutrophil and macrophage product, is important in bacterial killing, but a
Autor:
James A. Russell, John H. Boyd, Jason D. Christie, Katherine R. Thain, Keith R. Walley, Simone A. Thair, Jane F. Ferguson, Chris Fjell, Muredach P. Reilly, Mihai Cirstea, Taka-aki Nakada, Nuala J. Meyer
Publikováno v:
Science Translational Medicine. 6
A decrease in the activity of proprotein convertase subtilisin/kexin type 9 (PCSK9) increases the amount of low-density lipoprotein (LDL) receptors on liver cells and, therefore, LDL clearance. The clearance of lipids from pathogens is related to end
Publikováno v:
D57. SEPSIS: OF MICE, METABOLOMICS, AND MAN.
Publikováno v:
Thrombosis research. 130(3)
Introduction Genetic variation in the Protein C gene (PROC) is associated with altered risk of adverse outcome for a number of diseases. Common single nucleotide polymorphisms (SNPs) in the promoter region and the adjacent 5’ region of PROC are ass
Publikováno v:
C108. GENETICS AND FUNCTIONAL GENOMICS OF PULMONARY VASCULAR DISEASE.
Autor:
Hiroyuki Hirasawa, Emiri Nakada, Shigeto Oda, James A. Russell, Keith R. Walley, Simone A. Thair, John H. Boyd, Hugh Wellman, Katherine R. Thain, Taka-aki Nakada
Publikováno v:
Chest. 139(5)
Background Vasopressin is an essential peptide hormone regulating cardiovascular homeostasis and an adjunctive vasopressor therapy for septic shock. Methods We tested for association between single nucleotide polymorphisms (SNPs) in vasopressin pathw
Autor:
Keith R. Walley, Taka-aki Nakada, Melissa K. McConechy, Katherine R. Thain, John H. Boyd, Emiri Nakada, Rosalia Aguirre-Hernandez, James A. Russell, Simone A. Thair, Luke McLaughlin
Publikováno v:
A15. GENOMICS IN CRITICAL CARE: A COMING OF AGE.
Autor:
Katherine R. Thain, James A. Russell, Melissa K. McConechy, Rosalia Aguirre-Hernandez, Simone A. Thair, Keith R. Walley, Taka-aki Nakada, Emiri Nakada, John H. Boyd
Publikováno v:
American journal of respiratory and critical care medicine. 181(2)
The CysGlyGln haplotype of the beta(2)-adrenergic receptor gene (ADRB2) is functional and associated with altered responses to adrenergic agonists in patients with asthma. Whether this functional haplotype alters outcome in patients receiving adrener