Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Katherine Oliver"'
Autor:
Natalya Lukoyanova, Stephanie C Kondos, Irene Farabella, Ruby H P Law, Cyril F Reboul, Tom T Caradoc-Davies, Bradley A Spicer, Oded Kleifeld, Daouda A K Traore, Susan M Ekkel, Ilia Voskoboinik, Joseph A Trapani, Tamas Hatfaludi, Katherine Oliver, Eileen M Hotze, Rodney K Tweten, James C Whisstock, Maya Topf, Helen R Saibil, Michelle A Dunstone
Publikováno v:
PLoS Biology, Vol 13, Iss 2, p e1002049 (2015)
Membrane attack complex/perforin-like (MACPF) proteins comprise the largest superfamily of pore-forming proteins, playing crucial roles in immunity and pathogenesis. Soluble monomers assemble into large transmembrane pores via conformational transiti
Externí odkaz:
https://doaj.org/article/61da81d52f214c008c291f4ba889cd9a
Autor:
Damian J. Green, Asher Chanan-Khan, E. Ibrahim, J. Longcor, Natalie S. Callander, M.F. Brown, Sikander Ailawadhi, Patrick J. Stiff, Katherine Oliver, Jennifer L. Peterson, John Friend
Publikováno v:
Annals of Oncology. 32:S784-S785
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ee89790867947f5dd3614462cb81903
https://doi.org/10.1016/j.annonc.2021.08.150
https://doi.org/10.1016/j.annonc.2021.08.150
Autor:
Asher Chanan-Khan, Katherine Oliver, Jarrod Longcor, Matthew Francis Brown, Jennifer L. Peterson, John Friend, Damian J. Green, Sikander Ailawadhi
Publikováno v:
Journal of Clinical Oncology. 39:7561-7561
7561 Background: Phospholipid ethers (PLE) provide a novel mechanism to specifically target tumor cells leveraging high lipid raft content in their cell membranes. PLE/phospholipid drug conjugates are specifically designed to have high affinity to li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4698a96223c454fd13c3c2ac32434f94
https://doi.org/10.1200/jco.2021.39.15_suppl.7561
https://doi.org/10.1200/jco.2021.39.15_suppl.7561
Autor:
Jamey P. Weichert, Lance T. Hall, Scott B. Perlman, Joanne E. Mortimer, Sam J. Lubner, Glenn Liu, Jacqueline A. Mullvain, Michael J. Pishvaian, Katherine Oliver, Jennifer Heideman
Publikováno v:
Cancer Investigation. 33:483-489
This study explores the imaging and therapeutic properties of a novel radiopharmaceutical, (131)I-CLR1404. Phase 1a data demonstrated safety and tumor localization by SPECT-CT. This 1b study assessed safety, imaging characteristics, and possible anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536a9679ae8a60f783a91f8a88c65263
https://doi.org/10.3109/07357907.2015.1081691
https://doi.org/10.3109/07357907.2015.1081691
Publikováno v:
Annals of Oncology. 30:v435
Background Forty to fifty percent of newly diagnosed DLBCL patients will relapse and another 10% will be refractory to initial therapy. Despite the introduction of new therapies, outcomes for patients with R/R DLBCL remain poor with no improvement in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb960427798b6afe576a00fe25e0e95c
https://doi.org/10.1093/annonc/mdz251
https://doi.org/10.1093/annonc/mdz251
Autor:
Nikhil Sharma, Katherine Oliver
Publikováno v:
International Journal of Research in Medical Sciences. 6:2923
Background: Assessment of the tear film is necessary in routine clinical practice because an unstable tear film can hamper the quality of life by causing vision-related problems and compromising the ocular surface. One of the major concerns related t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05ba9b8dd2b2376f25377e5f8b5dbf30
https://doi.org/10.18203/2320-6012.ijrms20183628
https://doi.org/10.18203/2320-6012.ijrms20183628
Publikováno v:
Amino Acids. 38:1423-1428
Heat shock proteins play an important role as molecular chaperones of the cell. Inducible heat shock protein 70 is rapidly synthesised in response to numerous stressors and monocytes are sensitive to changes in core temperature resulting in a circadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2adaa74290646e8920d7e249e07459
https://doi.org/10.1007/s00726-009-0354-4
https://doi.org/10.1007/s00726-009-0354-4
Publikováno v:
Journal of Clinical Oncology. 35:e14087-e14087
e14087 Background: CLR 131 is a novel radioiodinated therapeutic that exploits the selective uptake and retention of phospholipid ethers (PLEs) by malignant cells. Study was to evaluate the therapeutic effect of CLR 131 when administered as a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f07fae1c78f291a2f9693a5e97f6d75a
https://doi.org/10.1200/jco.2017.35.15_suppl.e14087
https://doi.org/10.1200/jco.2017.35.15_suppl.e14087
Publikováno v:
Journal of Clinical Oncology. 35:e14089-e14089
e14089 Background: CLR 131 is a novel radioiodinated therapeutic that exploits the selective uptake and retention of phospholipid ethers (PLEs) by malignant cells. Study was to evaluate the therapeutic effect of CLR 131 when administered as a repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76eccecdbe6291610f3df7f1aa8f4423
https://doi.org/10.1200/jco.2017.35.15_suppl.e14089
https://doi.org/10.1200/jco.2017.35.15_suppl.e14089
Publikováno v:
Journal of Clinical Oncology. 35:e14091-e14091
e14091 Background: CLR 131 is a novel radioiodinated therapeutic that exploits the selective uptake and retention of phospholipid ethers (PLEs) by malignant cells. Uterine sarcoma (MES SA/Dx5) cells express high levels of P-gp and are known to be a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::657c296b4be9ff5dd11dcd9ad8bff121
https://doi.org/10.1200/jco.2017.35.15_suppl.e14091
https://doi.org/10.1200/jco.2017.35.15_suppl.e14091