Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Katherine Nutsch"'
Autor:
Yan Qu, Ira Mellman, Ellen Duong, Thomas D Wu, Eugene Y Chiang, Katherine Nutsch, Karl L Banta, Charles W Tran, Stephanie Mittman, Barzin Y Nabet, Namrata S Patil
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/5a68ddaf764c4d40afd06e0a458c6d04
Autor:
Emilie V Russler-Germain, Jaeu Yi, Shannon Young, Katherine Nutsch, Harikesh S Wong, Teresa L Ai, Jiani N Chai, Vivek Durai, Daniel H Kaplan, Ronald N Germain, Kenneth M Murphy, Chyi-Song Hsieh
Publikováno v:
eLife, Vol 10 (2021)
Generation of tolerogenic peripheral regulatory T (pTreg) cells is commonly thought to involve CD103+ gut dendritic cells (DCs), yet their role in commensal-reactive pTreg development is unclear. Using two Helicobacter-specific T cell receptor (TCR)
Externí odkaz:
https://doaj.org/article/007c449ec2de46e180b76c8533b9af29
Autor:
Katherine Nutsch, Jiani N. Chai, Teresa L. Ai, Emilie Russler-Germain, Taylor Feehley, Cathryn R. Nagler, Chyi-Song Hsieh
Publikováno v:
Cell Reports, Vol 17, Iss 1, Pp 206-220 (2016)
Commensal bacteria shape the colonic regulatory T (Treg) cell population required for intestinal tolerance. However, little is known about this process. Here, we use the transfer of naive commensal-reactive transgenic T cells expressing colonic Treg
Externí odkaz:
https://doaj.org/article/690c72d2b5f6466b998f8e2000e7dc66
Autor:
Shannon Young, Vivek Durai, Jiani N. Chai, Ronald N. Germain, Harikesh S. Wong, Jaeu Yi, Chyi-Song Hsieh, Daniel H. Kaplan, Emilie V. Russler-Germain, Kenneth M. Murphy, Teresa L. Ai, Katherine Nutsch
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Generation of tolerogenic peripheral regulatory T (pTreg) cells is commonly thought to involve CD103+ gut dendritic cells (DCs), yet their role in commensal-reactive pTreg development is unclear. Using two Helicobacter-specific T cell receptor (TCR)
Autor:
Jiani N. Chai, Shannon Young, Chyi-Song Hsieh, Katherine Nutsch, Jaeu Yi, Emilie V. Russler-Germain, Kenneth M. Murphy, Teresa L. Ai, Harikesh S. Wong, Ronald N. Germain, Vivek Durai, Daniel H. Kaplan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04aa754e9e0f657986211361dc4c6e1e
https://doi.org/10.7554/elife.54792.sa2
https://doi.org/10.7554/elife.54792.sa2
Autor:
Kenneth M. Murphy, Katherine Nutsch, Justin S. A. Perry, Andrew L. Kau, Jeffrey I. Gordon, Zhuo Yang, Chyi-Song Hsieh, Chan-Wang J. Lio
Publikováno v:
Immunity. 41(3):414-426
SummaryThe contribution of thymic antigen-presenting-cell (APC) subsets in selecting a self-tolerant T cell population remains unclear. We show that bone marrow (BM) APCs and medullary thymic epithelial cells (mTECs) played nonoverlapping roles in sh
Autor:
Sindhuja Rao, Nicole A. Santacruz, Stephanie K. Lathrop, Katherine Nutsch, Thaddeus S. Stappenbeck, Chyi-Song Hsieh, Seth M. Bloom, Daniel A. Peterson, Chan-Wang J. Lio
Publikováno v:
Nature
Understanding how the immune system becomes tolerant to foreign antigens from commensal bacteria is a fundamental question, as breakdown of tolerance can result in unwanted responses such as inflammatory bowel disease. It has been suggested that tole
Autor:
Anish Suri, Katherine Nutsch, Kenneth M. Murphy, Wataru Ise, Hyang Mi Lee, Masako Kohyama, Emil R. Unanue, Theresa L. Murphy
Publikováno v:
Nature Immunology. 11:129-135
The inhibitory immunoregulatory receptor CTLA-4 is critical in maintaining self-tolerance, but the mechanisms of its actions have remained controversial. Here we examined the antigen specificity of tissue-infiltrating CD4(+) T cells in Ctla4(-/-) mic
Autor:
Jennifer M. Lund, Pandelakis A. Koni, Andrew G. Farr, Jeffery P. Rasmussen, Adrian Liston, Alexander Y. Rudensky, Katherine Nutsch
Publikováno v:
Proceedings of the National Academy of Sciences. 105:11903-11908
Regulatory Foxp3+T cells (TR) are indispensable for preventing autoimmune pathology in multiple organs and tissues. During thymic differentiation T cell receptor (TCR)–ligand interactions within a certain increased affinity range, in conjunction wi
Autor:
Katherine Nutsch, Chyi-Song Hsieh
Publikováno v:
Current opinion in immunology. 24(4)
The commensal bacteria normally resident in the gastrointestinal tract represent an enormous pool of foreign antigen within the body. Although mechanical barriers limit entry of bacteria into the host, recent data suggest that T cells routinely inter